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(MT1) Large Biological Molecules
BIO 202.01
17
Biology
Undergraduate 2
09/23/2012

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Term

What are the four large molecules?

 

Which three of them are macromolecules?

Definition
  • Lipids
  • Carbohydrates
  • Proteins
  • Nucleic Acids 

All but lipids are macromolecules

Term
What makes up a carbohydrate? Give four examples.
Definition

Monosaccharides chain together to create disaccharides and polysaccharides through glycosidic linkages.

 

Examples:

  • starch
  • glycogen
  • cellulose
  • chitin
Term
What is starch and what is it used by?
Definition
Starch is polymers of glucose monomoers stored in chloroplasts of plants for energy.
Term
What is glycogen and what is it used by?
Definition
Glycogen is a glucose polymer stored by animals for energy.
Term
What is cellulose and what is it used by?
Definition
Cellulose is a beta glucose polymer. This means that the hydroxyl group on the 1-carbon is inverted, so everyother glucose molecule is flipped in order for dehyrdation reactions to occur and monomers to become polymers. It is used in plants, among other things, to create cell walls. 
Term
What is chitin and what is it used by?
Definition
Chitin is a beta glucose polymer like cellulose, except that its glucose monomer has a nitrogen-containing appendage. It is used in insects, among other things, to build exoskeletons.
Term
What is a lipid? Give three examples.
Definition

A lipid is a hydrogen-carbon containing compound that is ussually insoluble in water.

 

Examples:

  • fats
  • phospholipids
  • steroids
Term
What is fat made of? What is it used for?
Definition

Fat is made of glycerol binded through dehydration reactions to 3 fatty acids. Fatty acids are long hydrocarbon chains with a carboxyl group. This creates triacylglycerol.

 

Fat is used as cushion, to store energy and to fuel growth.

Term
What is a phospholipid made of? What purpose does it serve?
Definition

A phospholipid is a triacylglycerol covalently bonded to two fatty acids and a phosphate group. Because the phosphate group has a negative charge, it often attracts a positive molecule to form the head.

 

Phospholipids are used to create membranes, consisting of two rows of phospholipids, in cells. The hydrophobic tails are facing inward while the hydrophilic (polar) heads face the cytoplasm and outside of the cell.

Term
What is a steroid made of? What purpose does it serve?
Definition

A steroid is characterized by its four carbon rings fused to a varying chemical group.

 

An example of a steroid is a sex hormone.

Term
What is a protein and what function does it serve?
Definition
A protein is a polymer of amino acids which may consist of one or more polypeptides. They are a part of almost everything that happens in a cell.
Term
What is an amino acid made of? What purpose does it serve?
Definition

An amino acid is a molecule containing a central carbon attached to a hydrogen, an amino group, a carboxyl group, and a varying side chain. Polymers of amino acids create proteins.

 

There are 20 in total and are linked through peptide bonds.

Term
What are the four levels of protein structure? What type of bonds are involved with each?
Definition

1. Primary structure - The sequence of the amino acid backbones bound together through covalent peptide bonds.

 

2. The alpha helix and beta pleated sheet structures - Hydrogen bonds between every fourth amino acid create an alpha helix or beta pleated sheet structure.

 

3. The overall polypeptide shape - Side chain interactions (hydrogen bonds, covalent bonds, ionic bonds) give the polypeptide its shape.

 

4. (only some proteins) Polypeptides coming together - Polypeptides join through hydrogen, covalent, and ionic bonds. Either a globular or fibrous shape is created.

Term
What does it mean to denature and renature a protein?
Definition
A protein is denatured when exposed to severe conditions such as high temperature. This causes the protein to become unfolded. Proteins can be renatured its enviornment is restored to normal or with the help of chaperonin protein.
Term
What are nucleic acids made of? What functions do they serve?
Definition

Nucleic acids are polymers of nucleotides. Nucleic acids are used in DNA.

 

Nucleotides are attached via the 5' or 3' carbon on the sugar molecule. When reading a strand of DNA or RNA, the nitrogenous bases are read from 5' (the phosphate group) to 3' (the OH group). 

Term
What is a nucleotide made of? What functions do they serve?
Definition

Nucleotides have two main components:

  • A nucleoside, consiting of a nitrogenous base and a ribose molecule in RNA and a deoxyribose molecule in DNA
  • A phosphate group
Term
What are the nitrogenous bases in nucleotides? Which bases pair with which?
Definition

The five nitrogenous bases:

  • Adenine (A)
  • Cytosine (C) 
  • Guanine (G)
  • Thymine (T, ONLY IN DNA)
  • Uracil (U, ONLY IN RNA)

Adenine pairs with Thymine OR Uracil

Cytosine pairs with Guanine

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