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Lab Exam 1
Lab Exam 1
80
Physiology
Undergraduate 2
02/24/2011

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Term
Dynamic Equilibrium
Definition
Fluctuation within an acceptable range around the set point as the external temperature or the level of activity changes.
Term
Homeostasis
Definition
The maintenance of a relatively constant internal condition in spite of variations in the environment.
Term
Negative Feedback Inhibition
Definition
Maintains the dynamic equilibrium within a close range around the set point. Occurs when the output of a system sends a signal that causes the system to reverse its direction.
Term
Normal Body temperature range
Definition
98.4 to 98.6
Term
Positive Feedback
Definition
Occurs when the output of a system sends a signal that causes the system to continue in the same direction.
Term
Five components to the Patellar Reflex Arc
Definition
1. Receptor (stretch on quads)
2. Afferent sensory nuerons
3. Integration in CNS
4. Efferent Motor Nuerons
5. Skeletal Muscle (Effector)
Term
Where is the cell body of Afferent neurons located? Efferent cell body?
Definition
1. in PNS
2. in CNS
Term
1.Somatic?
2.Autonomic?
Definition
1. skeletal muscle
2. Glands, smooth muscle, cardiac muscle
Term
Hypothalamus releases what hormone?
Definition
Thyrotropin releasing hormone
Term
Anterior Pituitary releases what hormone?
Definition
Thyroid stimulating hormone
Term
Thyroid gland releases what hormone?
Definition
Thyroid hormone
Term
Five components of Baroreceptor reflex
Definition
1. Hypotension (stretch of BV)
2. afferent neurons
3. integration in CNS
4. efferent neurons
5. effectors
Term
what are the effectors of the baroreceptor reflex?
Definition
1.SA Node-controls heart rate
2.Heart Muscle-controls stroke volume
3. Blood vessels
Term
1.where does CNS integration occur for baroreceptor reflex?
2.1.where does CNS integration occur for patellar reflex?
Definition
1.medulla oblangata
2.spine
Term
Where are the baroreceptors located
Definition
coratid sinuses and aortic arch
Term
pH7 means what?
Definition
That there are an equal amount of hydrogen and hydroxyl ions
Term
What are the two things that an acidic solution contain?
Definition
1. More hydrogen ions than hydroxyl ions
2. More hydrogen ions than at a pH7
Term
What are the two things that an basic solution contain?
Definition
1. Less hydrogen ions than hydroxyl ions
2. Less hydrogen than a pH7 solution
Term
What is the ideal range for pH
Definition
7.35 to 7.45
Term
For every unit change, hydrogens are increased by what number?
Definition
10x
i.e. 11 to 8= 1000x
Term
Diffusion
Definition
Movement of molecules from higher to lower concentration...more to less
Term
Which factors increase the rate of diffusion?
What factors determine the rate of diffusion?
Definition
1. High temperature
2. Temperature,concentration, size, and temperature of the molecules or ions
Term
What is the driving force behind diffusion?
Definition
kinetic energy
Term
Osmosis
Definition
Diffusion of water and the movement of water into and out of cells
Term
semipermeable membrane
Definition
allows certain molecules or ions to pass through it bu diffusion
Term
Hypotonic
Definition
more water
Term
What is crenation
Definition
The notches around the cell that appear when the cell shrinks; due to water moving ou of cell
Term
Hemolysis?
Definition
Bursting of cell; due to water moving inside cell
Term
Was Toluene soluble?
Was it hydrophobic?
Definition
1. no
2. yes
Term
Was KMnO4 hydrophobic or hydrophilic?
Definition
Hydrophilic bc it was soluble in H2O
Term
When a solute mixes with water it is called?
What is it called when it is not soluble in water?
Definition
1.Hydrophilic
2. Hydrophobic
Term
Is detergent Hydrophilic or hydrophobic
Definition
Term
What are the factors of molecules that can pass through the phospholipd membrane easily?
Definition
Small molecule
hydrophobic
nonpolar
Term
What are the factors of molecules that can NOT pass through the phospholipd membrane easily?
Definition
Large molecules
Polar
Hydrophilic
Term
Where is Pepsin produced?
Definition
stomach, pH1-3
Term
Where is Trypsin produced?
Definition
Pancreas, pH 6-8
Term
Enzymes break down ____ to _____.
Definition
Substrates to products
i.e. H2o2= H2o and O2
Term
Enzymes are specific to its ___ and are also called ____. They are known to ____up reaction times without the enzyme itself being altered by the chemical.Enzymes are reusable. Enzymes need ___, minerals and _____ to function correctly.
Definition
substrate
catalyst
speed
vitamins
heavy metals
Term
Enzymes are a _____ structure. So 2000 enzymes = ____structures.
Most enzymes end with ____
Definition
quaternary
500
"ase"
Term
The larger the concentration of substrates...
Definition
The larger the enzyme activity
Term
Heavy metals...
Definition
interfere with the bonding of a enzyme with its substrate
Term
Cofactors...
Definition
help shape the active site of some enzymes
Term
Coenzymes...
Definition
are water soluble vitamins that bond to active site and promote the chemical reaction that yields the final product.
Term
enzyme activity ____ with temperature
If too high, the enzyme will ___: this is how heat sterilization kills bacteria.
Definition
increases
denature
Term
what causes the bonds between amino acids to break?
Definition
denaturing
Term
One molecule of catalase(enzyme) breaks down 6 million molecules of H2O2(hydrogen peroxide) to H2O and O2 each minute. Thats 100,000/second
Definition
Glucose is broken down to CO2 and H2O which is then released as heat and stored as ATP.
Term
Where is catalase found?
Definition
peroxisomes (bc they break down H2O2)
Term
What syndrome is caused by malformed peroxisomes?
Definition
Zellweger's Syndrome
Term
How does a high or low pH affect an individual enzyme molecule?

How does smaller surface areas affect reaction?
Definition
Increases rate of reaction
Increases rate of reaction
Term
Enzymes are produced as a direct result of what process?
Definition
Condensation in the ribosomes
Term
Why do proteins need to be globular for functionality (physiologically)
Definition
so they can form active sites
Term
One thousand microns equals how many mm?
Definition
1000
Term
1mm3 equals how many microliters?
Definition
1
Term
1 liter equals a quart
Definition
nanometer=1/1,000,000
Term
1 micron equals how many nanometers?
Definition
1000 (3 places away)
Term
1m=
Definition
1,000,000 um
Term
1m=
Definition
1,000,000,000
Term
king henry drinks ucky dark chocolate milk
Definition
kilo, hecto, deka, unit(meter,liter,gram), deci, centi, mili
Term
cc=mm
Definition
Term
u (micron) is three places down past mili
nano is 6 places down past mili
Definition
1m=1,000um
1m=1,000,000
Term
What is hematocrit
Definition
Is a measurement of the relative percentage of RBCs in a given volume of whole blood.
Term
how do you determine the hematocrit %
Definition
height of column of RBC x 100/
height of column of RBC + plasma
Term
Polycythemia?
Definition
too much rbc=more than 45%
Term
anemia?
Definition
too little rbc=less than 45%
therefore decrease in oxygen carrying capacity. Most common causes is diet, chronic blood loss and iron defiecency
Term
What are the two causes of high hematocrit?
Definition
Polycythemia due to too many RBC's and dehydration due to too much plasma.
Term
What are the forces involved in capillary action?
Definition
adhesive action
Term
Hemoglobin has ____ amino acids, ___heme groups and ___iron atoms. Each iron atom carries ___ O2 molecule. How many hemoglobin molecules are in a RBC?
how many tertiary structures make up the quaternary structure of hemoglobin?
Definition
574,4,4,1,
280 million
4
Term
RBCs main function is...
Definition
to transport CO2 and O2. They live for 120 days and are then ingested by phagocytic cells in the liver and spleen.
Term
WBCs main function is to...
Definition
defend against infections and clean up the debris in areas of inflammation.
Term
Platelets are vital for...
Definition
coagulation. When platelet count is too low, the blood fails to clot.
Term
Cholesterol is synthesized by the ___ and obtained by ____.Cholesterol is hydrophobic so it must be transported by hydrophilic proteins. Lipoproteins are a combination of ___ and ___.
Definition
Liver
diet
protein carrier and cholesterol.
Term
VLDL
Transports cholesterol that is synthesized in the ____.
It is converted in the bloodstream to ___.
Definition
Very low density lipoproteins.
Liver.
LDL
Term
LDL is the cholesterol rich remnant of VLDL.
Definition
There is a high correlation between high levels of LDL and heart disease.
Term
HDL
Definition
inhibits the cell uptake of LDL and it removes and transports cholesterol from the tissues back to liver excretion.
Term
Triglycerides main function is...
Definition
insulate,protect, and provide cellular energy.
Term
What is CRP
Definition
C reactive Protein-a test used for assessing the risk of heart disease by identifying the presence of inflammation.
Term
What is hemophilia?
Definition
a genetic disease caused by the lack of clotting proteins in the blood
Term
What is the difference of thrombosis and embolism
Definition
They are both clotting of the arteries however the clot moves to different parts of the body in embolism
Term
Two sources of cholesterol and triglycerides
Definition
liver and diet
Term
Two sources of cholesterol and triglycerides
Definition
liver and diet
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