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Lab 1: Respiratory System/Spirometry
Study Stack
49
Anatomy
Undergraduate 3
01/18/2015

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Cards

Term
Upper Respiratory Tract
Definition
Nose, Nasal Cavity, Pharynx
Term
Anatomy of Respiratory System
Definition
Nose, Nasal Cavity, Pharynx, Larynx, Trachea, Primary Bronchi, Secondary Bronchi, Tertiary Bronchi, Bronchioles, Terminal Bronchioles, Alveolar Ducts, Alveolar Sacs
Term
Lower Respiratory Tract
Definition
Larynx, Trachea, Bronchial Tree, Lungs
Term
Mucociliary escalator
Definition
ciliated epithelium serves to sweep inhaled particles out of the respiratory tract into the pharynx
Term
4 Major Components of Respiratory Membrane
Definition
1.Pulmonary Surfactant
2.Alveolar Epithelium consisting of squamous epithelial cells on their on basement membrane
3.Thin interstitial space between the alveolar epithelium and the pulmonary capillary
4.Vascular Endothelial Cells of the capillary wall which may fuse with alveolar epithelial basement membrane
Term
What can be measured with a spirometer?
Definition
1.Tidal Volume
2.Inspiratory Reserve Volume
3.Expiratory Reserve Volume
4.Vital capacity
5.Inspiratory Capacity
Term
What cannot be measured with spirometer?
Definition
1.Residual Volume
2.Functional residual capacity
Term
Tidal Volume
Definition
volume of air moved in or out of the lungs during quiet breathing
Term
Inspiratory Reserve Volume
Definition
Volume of Air a person is capable of inhaling after normal inspiration
Term
Expiratory Reserve Volume
Definition
Volume of Air a person is capable of exhaling after normal expiration
Term
Vital Capacity
Definition
TV + IRV + ERV
Term
Residual Volume
Definition
(RV) volume of air remaining in the lungs after a person has exhaled as much as possible
Term
Total Lung Capacity
Definition
(TLC) is vital capcacity plus residual volume
Term
Inspiratory Capacity
Definition
amount of air that can be inhaled after a normal expiration
Term
Functional Residual capacity
Definition
volume of air in lungs after a normal expiration
Term
What determines elasticity of the lungs?
Definition
1.Amount of cartilage usually decreases/disappears in bronchioles
2.Walls of bronchi acquire layer of smooth muscle and connective tissue that is rich in elastic fibers.
Term
What cells secrete pulmonary surfactant?
Definition
Type 2 Alveolar Epithelial Cells
Term
Composition of Pulmonary Surfactants and what does it do?
Definition
Proteins (90%)
Lipids (10%)
Helps decrease surface tension so alveoli can inflate
Term
Expiration Muscles
Definition
1.Abdominal Wall Muscles contract during coughing, vomitting, pooping
*Contract= raise pressure in abdominal cavity, pushing diaphragm up into thoracic cavity
2.Internal Intercostals: muscles act in opposite way to the external intercostals. Ribs are pulled downwards, backwards, and inwards
Term
Inspiration Muscles
Definition
1.Diaphragm innervated by phrenic nerves that originate in the cervical plexuses. CONTRACTS by moving downwards and enlarges volume of the thoracic cavity

2.External Intercostal Muscles: contraction pulls ribs upwards, forwards and outwards

3.Accessory Muscles: Contract during exercise such as scalene muscles of neck and the sternocleidomastoideus.
Term
Function of Chemoreceptors
Definition
Monitor Carbon Dioxide, pH, and oxygen levels of the arterial blood. Occur centrally in medulla where they respond to pH and peripherally in small bodies associated with carotid artery and aorta, where they respond mainly to changes in partial pressure of oxygen.
Term
Control of Respiration
Definition
Central Controller---> Effector Muscles---->
Sensors
Term
medullary chemoreceptors
Definition
respond to fall of pH of the brain extracellular fluid bathing them when blood CO2 rises
Term
peripheral chemoreceptors
Definition
low arterial partial pressure of oxygen
Term
Bronchial Asthma
Definition
reversible disease caused by allergic reaction to allergens in the air.
-cells lining respiratory tract secrete an excessive amount of mucus which obstructs the airway
-bronchi and bronchioles, decrease their diameter (smooth muscle constricts)
Term
Emphysema
Definition
elastic tissue of alveoli replaced with connective tissue. Alveoli remain inflated and expiration is difficult which creates lower concentration of oxygen in the blood
Term
Pneumonia
Definition
alveoli become infected and inflamed and fill with fluid and dead white blood cells. Oxygen has hard time diffusing from lung to capillaries surrounding an alveolus
Term
Lung Cancer
Definition
uncontrolled cell proliferation of cells lining the respiratory passages; damage cilia too. goblet cells secrete excess mucus.
Term
FEV/FVC Obstructive
Definition
Less than 80 percent
Asthma, Bronchitis, Emphysema,(COPD)
Term
FEV/FVC Restrictive
Definition
More than 80 percent
-Mucus membrane infected (Pulmonary Fibrosis)
Term
thyroid cartilage
Definition
forms sidewalls of the larynx as well as the adam's apple
Term
cricoid cartilage
Definition
inferior to thyroid cartilage
Term
Tidal Volume
Definition
volume of air moved in or out of the lungs during quiet breathing (500mL)
Term
Inspiratory Reserve Volume
Definition
volume of air that can be inhaled past a normal inspiration (3000mL)
Term
Expiratory Reserve Volume
Definition
volume of air that can be exhaled past a normal expiration (1100mL)
Term
Residual Volume
Definition
volume of air that remains in lungs at all times (1200mL)
Term
Inspiratory Capacity
Definition
TV + IRV amount of air that can be inhaled after a normal expiration
Term
Vital Capacity
Definition
(TV + IRV + ERV) or (TLC-RV)

amount of air that can be exhaled after max inhalation (4600mL)
Term
Functional Residual Capacity
Definition
ERV + RV; volume of gas in lung after normal expiration (2300mL)
Term
Total Lung Capacity
Definition
VC+RV; total volume of air the lungs can hold (5800-6000mL)
Term
Forced Expiratory Volume (FEV)
Definition
volume of air that can be forcefully exhaled in one second. (80% of FVC)
Term
Forced Vital Capacity (FVC)
Definition
maximum amount of air that can be forcefully exhaled after max inhalation
Term
peripheral chemoreceptors associated with
Definition
carotid artery and aorta where they respond to changes in pO2
Term
medullary chemoreceptors montiors
Definition
decrease in PH and increase in Carbon Dioxide
Term
nasal cavity and nasopharynx house
Definition
pseudostratified ciliated columnar (contains goblet cells)
Term
oropharynx and laryngopharynx
Definition
striated squamous epithelium
Term
larynx
Definition
above vocal cords: stratified squamous
below vocal cords: pseudostratified ciliated columnar epithelium
Term
trachea
Definition
pseudostratified ciliated columnar epithelium
Term
terminal bronchioles
Definition
simple cuboidal epithelium
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