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Lab 13: Cardiovascular System 2
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32
Biology
Undergraduate 3
12/08/2014

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Term
Stage 1. Ventricular Filling
Definition
atria and ventricles relaxed
mitral and tricuspid valves wide open
*aortic and semilunar valves closed
*blood rushes passively from venae cavae to atria to ventricles
*70 percent of filling here
Term
Stage 2: Atrial Systole
Definition
atria contract; topping amount of blood filled in ventricles by another 30 percent which will fill them completely.
-atria then relax which is a stage known as atrial diastole
Term
Stage 3: Isovolumic Ventricular Contraction
Definition
S1 SOUND
-First phase of ventricular systole
-ventricles contract, pressure rises in their interiors and exceeds pressure in the atria which cause AV valves to close.
Term
Stage 4: Ejection into Aorta
Definition
Pressure in ventricles>Pressure in Pulmonary Artery/Aorta
Which Causes: semilunar valves to passively open and blood is ejected out from ventricles into pulmonary systemic circuits
Term
Stage 5: Isovolumic ventircular Relaxation
Definition
S2 SOUND
-Pressure in ventricles starts to fall below pressure in pulmonary arteries and aorta.
CAUSES: semilunar valves close passively and pressure in ventricles starts to fall. ALL 4 VALVES CLOSED
Term
Stage 6: Ventricular Filling Again
Definition
Pressure in ventricles falls below pressure in atria.
CAUSES: A-V valves to open, causing blood to enter into relaxed ventricles.
Term
Heart Sounds S1
Definition
onset of ventricular systole; closure of A-V valves and tensing of chordae tendinae
(mitral valve closes ahead of tricuspid valve)
Term
Heart Sounds S2
Definition
occurs when semilunar valves close and marks the end of the ventricular systole. (aortic valve closes ahead of pulmonic valve)
Term
Systolic Murmur
Definition
mitral valve defect; blood regurgitates into corresponding atrium during ventricular systole. LV pressure > LA pressure
Term
Diastolic Murmur
Definition
Aortic or Pulmonic Valves do not close properly. Blood regurgitates into ventricles during ventricular diastole. Pulmonic and aortic valves should be closed.
Term
4 Factors that Affect Cardiac Output
Definition
1. Preload
2. Afterload
3. Heartrate
4. Myocardial Contractility
Term
Preload
Definition
amount of blood returning to heart (EDV)
Term
Afterload
Definition
resistance to ejection of blood from ventricles
Term
3 Factors afterload is affected by Afterload
Definition
1. Pressure in the aorta
2. TPR determined by arteriole diameters and by vasoconstriction
3. Pathological Changes
Term
Myocardial Contractility
Definition
Force of contraction of cardiac muscle at given fiber length.
Term
3 factors affecting myocardial contractility
Definition
1. Norepinephrine and Epinephrine
2. Increased extracellular calcium
3. Digitalis: Causes increased intracellular calcium
Term
4 Factors that Determine Blood Pressure
Definition
1. Cardiac Output
2. TPR
3. Capacity of Venous System
4. Volume of Fluid in Circulatory System
Term
Baroreceptors
Definition
stretch receptors in walls of arteries
Term
Contraction of Myocardium
Definition
1.Triggered by rhythmic depolarization of the cells in the SA node
2. Spreads to ventricles via specialized myocardial cells that make up the conduction system of the heart
3. Myocardium depolarized, process of repolarization begins. Apical surface myocardium repolarizes little earlier than basal region.
Term
P-Wave
Definition
depolarization of the atria, indicates SA node function
Term
P-R interval
Definition
time it takes impulse to pass through the
A-V node into the ventricles
Term
QRS Complex
Definition
time when ventricular depolarization begins
Term
ST segment
Definition
between QRS complex and T wave. Used for diagnostic purposes. Elevation or depression with respect to baseline can be important in detecting myocardial infarction.
Term
T Wave
Definition
Re-polarization of the ventricles and are ready to be stimulated again.
INVERSION= myocardial infarction
Term
Stroke Volume Equation
Definition
EDV-ESV
Term
Pulse Pressure
Definition
Systolic Aortic Pressure - Diastolic Aortic Pressure
Term
Mean Blood Pressure
Definition
Diastolic Aortic Pressure + 1/3 Pulse Pressure
Term
Cardiac Output
Definition
HR x SV
Term
TPR
Definition
Mean Blood Pressure/Cardiac Output
Term
Mean Blood Pressure
Definition
Cardiac Output x TPR
Term
Ejection Fraction
Definition
SV/EDV
Term
Increased SV will
Definition
Cause Cardiac Output to increase more.
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