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kristen papers
thanks kristen
201
Medical
Undergraduate 4
06/02/2017

Additional Medical Flashcards

 


 

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Term
ECG changes that occur in stemi (4)
Definition
ST elevation
pathological Q waves
T wave inversion
hyperacute T waves
Term
initial mx of stemi
Definition
aspirin 300mg
sublingual glycerate trinitrate
morphine + antiemetic
O2 if sats < 94%
clopidogrel
Term
what is the time limit to offer PCI in?
Definition
within 12 hours of presentation if it can be delivered within 120 minutes.
Term
secondary prevention medications after MI
Definition
Aspirin
beta blocker
statin
ace-inhibitor
clopidogrel
Term
in HF with reduced ejection fraction which two drugs should be initiated?
Definition
ACE-I and beta blocker
Term
2nd line drug treatment in HF?
Definition
spironolactone
ARB
Hydralazine in combination with nitrate
Term
mx of pulmonary oedema in HF?
mneumonic is IPODMAN
Definition
iv access
position upright
oxygen
diuretics furosemide
morphine
antiemetic
nitrates: GTN infusion if SBP >110 or 2 puffs if SBP> 90
Term
ECG signs associated with AF?
Definition
absent P waves
tachycardia
irregularly irregular rhythm
Term
options for rate control in AF
Definition
rate limiting Ca channel blocker such as diltiazem or verapamil
or
beta blocker
Term
Score of 2 on CHA2DS2VASc so we offer anticoagulation. what are the options?
Definition
Warfarin
NOACS: apixiban, digabatrin, rivaroxiban
Term
two major criteria for endocarditis?
Definition
positive blood culture
evidence of endocardial involvement such as echocardiogram showing vegetations
Term
5 points from the minor criteria to diagnose IE
Definition
microbiological evidence that does not meet major criteria
fever >38
predisposing heart condition or IVDU
vascular phenomena: emboli, splinter haemorrhages, clubbing
immunological phenomena: rots spots, osiers nodes
Term
risk factors for IE
Definition
rheumatic heart disease
prosthetic valves
IVDU
congenital heart defects
Term
what does modified dukes criteria rehire to diagnose IE?
Definition
2 major or
5 minor or
1 major 3 minor criteria
Term
organisms that commonly cause IE?
Definition
staph aureus
Strep viridians
Staph epidermis
Term
lifestyle advice for HTN
Definition
lose weight
exercise more
stop smoking
reduce coffee and caffeine rick products
moderation of alcohol
reduce salt
relaxation therapies
Term
examinations to grade exacerbation of asthma?
Definition
Resp rate
Pulse rate
O2 sats
PEFR
respiratory exam
Term
mx of asthma exacerbation that does not need admission?
Definition
nebulised salbutamol
PO prednisolone short course
follow up 48 hours
Term
side effects of SABA?
Definition
fine tremor
headache
muscle cramp
tachycardia
Term
you suspect COPD in a pt, name 3 ix and why to confirm diagnosis?
Definition
post bronchodilator spirometry: obstructive airway severity and confirm diagnosis
FBC: aneamia or secondary polycythaemia
CXR: hyperinflation or to exclude other pathology
Term
organisms that commonly infect people with COPD?
Definition
haemophilus influenza
strep pneumonia
moraxella catarrhalis
Term
exacerbation of COPD, how to mx

NB: not infective
Definition
increase bronchodilator therapy, consider negs
PO pred 30mg 7-14 days

do not give Abx if it is not infective exacerbation of copd
Term
CURB score of 2 how to mx non pharmacologically a 82 year old smoker?

pharmacologically?
Definition
rest, fluids, stop smoking advice

pharmacological: amoxicillin and clarithromycin dual therapy or Doxycycline mono therapy.
Term
pt information to give when rx for pneumonia
Definition
1 week: fever should have resolved

4 weeks: chest pain and sputum production should have substantially reduced

6 weeks: cough and breathlessness should have substantially reduced

3 months: most symptoms should have resolved but fatigue may still be present

6 months: most people will feel back to normal.
Term
what are the 2 major types of lung cancer and which one is more common/.
Definition
small cell
non small cell

more common: non small cell
Term
clinical signs on examination for lung cancer?
Definition
cachexia
tracheal deviation
Hoarseness of voice
stridor
clubbing
ptosis
lymphadenopathy
tachypnoea
Term
reason for unilateral ptosis in someone with suspected lung cancer?
Definition
pancoast tumour, in apical lung. affects T1 nerve root
Term
which sites do lung cancer most commonly metastasise to?
Definition
CNS
Bone
Liver
Adrenal
Term
name 3 risk factors for developing type 2 diabetes?
Definition
obesity
previous gestational diabetes
ethnicity Black or asia
FHX
lack of physical activity
drugs such as thiazide diuretics and corticosteroids
Term
GP organises HBA1c for pt to diagnose diabetes. what level would confirm diagnosis?
Definition
6.5% 48mmol
Term
a pt has just been diagnosed with type 2 diabetes, what lifestyle advice would you give her?
Definition
education about the condition
dietary advise
exercise alcohol intake
smoking cessation if appropriate
education programs such as DESMOND
Term
pt has started on metformin, what SE should they be warned about?
Definition
diarrhoea, nausea, anorexia
Term
once stable how often should HBA1c be measured?
Definition
6 months
Term
what options are available for second line drugs if metformin isn't controlling diabetes?
Definition
gliptin - DPP-4 inhibitor eg vildagliptin
sulfonyurea - gliclazide, glibenclamide
pioglitazone: reduces insulin resitance and improves insulin sensitivity
Term
Gliptins eg Vildagliptin

MOA?
the enzyme they inhibit usually breaks down incretin. what does incretin do?
Definition
DPP-4 inhibitor. DPP4 is an enzyme that usually breaks down incretin.

incretin helps body produce more insulin only when it is needed and reduce the amount of glucose being produced by the liver when it is not needed.
Term
what are people with diabetes screens for every year?
Definition
retinopathy
diabetic foot
cvd risk factors
nephropathy
Term
3 causes of hypothyroidism
Definition
Hashimotos
De quervains
drugs: lithium, amiodarone, carbimazole
post thyroidectomy
iodine deficiency
Term
examination sigs suggestive of hypothyroid
Definition
dry coarse hair and skin
hoarse voice
delayed relaxation of deep tendon reflexes
periorbital oedema
goitre
bradycardia
paraesthesia due to carpal tunnel syndrome
Term
after an initial review when starting thyroxine how often should TFTs be measures?
Definition
4-6 months
Term
how to differentiate crohns from UC on clinical exam?
Definition
mouth ulcers
anal tags fistulas
arthritis
abdominal mass in right iliac fossa
Term
features on colonoscopy that fit with a diagnosis of Crohns
Definition
deep ulcers
skip lesions
Term
what life style advice would you give to someone diagnosed with crohns?
Definition
stop smoking if applicable
to return to clinic to discuss rx before trying for a family, contraception
Term
what is used to induce remission in Crohns?
Definition
corticosteroids
Term
what is used to maintain remission in Crohns?
Definition
aminosalicylates eg mesalazine
immunosuppressant eg MTX, azathioprine
Term
red flag signs in someone who presented with IBS
Definition
unexplained weight loss
rectal mass
aneamia
change of bowel motion becoming looser or more frequent for > 6 weeks in someone aged 60 years or more
rectal bleeding
abdominal mass
FHX of cancer ovaries/CRC
Term
what can be tested for in the stool to differentiate IBS from IBD?
Definition
faecal calprotectin
Term
lifestyle advice given to those with IBS
Definition
reduce fibre intake
take time to eat food
drink 8 cups of water a day
restrict tea/coffee to 3 cups a day
exercise: moderate intensity 30mins at least 5 days of the week
Term
medication to treat abdominal pain in IBS described as spasms
Definition
antispasmodic: mebeverine 135mg tds
alverine
peppermint oil
Term
diarrhoea in IBS what medication?
Definition
loperamide antimotility drug
Term
2nd line options for IBS
Definition
TCA
SSRI
Term
how to asses malnutrition on examination in someone
Definition
BMI
waist circumference
Term
tests for coeliac disease
Definition
Tissue transglutaminaseantibody TGA
Total IgA
endomysial antibody
Term
what should you ensure before testing someone for coeliacs disease?
Definition
ensure the person has eaten gluten containing food at least twice everyday for the past 6 weeks

gluten in in wheat, barley and rye
Term
there are a number of conditions associated with coeliacs. name them and tests you can do to exclude them
Definition
FBC and ferritin to screen for anemia
TFT for auto immune thyroiditis
LFTs to screen for autoimmune hepatitis
electrolytes for Addisons disease
Term
someone with coeliacs get pregnant. what dose folic acid would they need to be on?
Definition
5mg
Term
name one method of assessing a pt with coeliacs for risk of osteoporosis?
Definition
dexa
frax
qfracture
Term
name 2 renal/intrinsic causes of AKI?
Definition
Acute tubular necrosis
glomerulonephritis
contrast induced nephropathy-iodine
rhabdomyolysis
tumour lysis syndrome
Term
name 2 post renal causes of AKI
Definition
renal stones
BPH
bladder stones
cancer of bladder, urethra, prostate
Term
name some drugs that can cause AKI
Definition
aminoglycosides
cyclophosphamide
NSAIDs
furosemide
penicillamine
thiazide diuretics
Term
Signs of acute renal failure
Definition
reduced urine output
pulmonary oedema
ECG chnages due to hyperkalemia or acid base disturbances
ureamia eg pericarditis
Term
ECH changes associated with Hyperkalemia
Definition
tall tented T waves
small P waves
widened QRS complexes leading to sinusoidal pattern
prolonged PR interval
Term
indications for RRT?
Definition
diuretic resistant pulmonary oedema
hyperkalemia refractory to medical therapy
metabolic acidosis refractory to therapy
ureamic complications eg pericarditis, encephalopathy, bleeding
Term
stages of chronic kidney disesase
Definition
90 =1
60 =2
45= 3
30=4
<15 = esrf
Term
causes of CKD
Definition
hypertension
diabetes
glomerulonephritis
polycystic kidney disease
chronic pyelonephritis
renal artery stenosis
vasculitis
Term
symptoms of CKD remember 5Ps

SOB- pulmonary oedema
lethargy and bone pain - PTH over activity and renal osteodystrophy
peripheral neuropathy - amylodosis
itching - ureamia
Definition
parathyroid overactivity
pruritus
pigmentation
peripheral neuropathy
pulmonary oedema
Term
complications of CKD
Definition
hypertension
anemia
renal osteodytrophy
cardiovascular disease: MI, angina
calcium low phosphate high
acidosis
malnutrition
hyperlipideamia
Term
by what mechanism does anemia occur in CKD?
Definition
decreased EPO secretion
Term
in CKD which kind of hyperparathyroidism occurs?
Definition
secondary (to renal disease)
Term
complications of continuous ambulatory peritoneal dialysis?
Definition
infection
peritonitis with staphy epidermis
mechanical problems with fluid drainage
Term
causes of microcytic anemia?
Definition
fe deficiencey
thalassemia
congenital sideroblastic anemia
lead poisoning
Term
causes of macrocytic anemia?
Definition
B12 deficiency
folate deficiency
alcohol
hypothyroid
pregnancy
reticulocytosis
liver disease
Term
causes of polycytheamia. it can be relative or secondary true polycythemia
Definition
secondary causes:
due to hypoxia: COPD, altitude, smoking
inappropriate EPO making: due tor enal artery stenosis, renal cancer

relative polycythemia
due to burns, D+V, diuretics, Gaisbock syndrome
Term
gaisbock syndrome
Definition
secondary polycythemia that occurs in males who have a sedentary lifestyle and are on a high calorie diet
Term
what mutation do 90% of people with polycythemia rubra vera have?

(jack has it too)
Definition
JAK2 (jak has it 2)
Term
causes of haemolytic anaemia
Definition
autoimmune
sphrerocytosis
elliptocytosis
sickle cell disease
glucose-6-phosphate deficieny
thallasaemia
Term
multiple myeloma is cancer in which type of cells?
Definition
plasma cells
Term
what are the clinical features of multiple myeloma?
Definition
backpain, osteoporosis, pathalogical fractures
lethargy
renal failure
amyloidosis
hypercalcamia
carpal tunnel, neuropathy
hyperviscosity
Term
name of urinary protein we look for in multiple myelopma?
Definition
Bence-Jones protein
Term
mx of hypercalceamia?
Definition
IV fluids to rehydrate
IV bisphosphonate eg palmindronate
Term
what tests detect HIV?
Definition
p24 antigen
combined HIV antibody
Term
complications of HIV
Definition
progression to aids
pulmonary infection: pnuemocytis jirovecio
CNS infections: toxoplasmosis, cryptococcal meningitis
occular disease: CMV retinitis
tumours: Kaposis, non hodgkins
GI;oesophageal candidiasis, oral hairy leukoplakia
Term
HIV protease inhibitor (PI) drugs have the ending -naviir.

give some examples of PI
Definition
indinavir
ritonavir
nelfinavir
Term
Zidovudine is an example of which type of HIV drug?
Definition
nucleoside analogue reverse transcriptase inhibitor

other examples lamividune, didanosine
Term
lamivudine, didanosine and zidovudine are examples of which HIV drugs?
Definition
nucleoside analogue reverse transcritptase inhibitors
Term
give an example of a non nucleoside analogue reverse transcriptase inhibitor?
Definition
Nevirapine
Efavirenz
Term
nevirapine
efavirenz are?
Definition
non nucleoside analogue reverse transcriptase inhibitors used in HIV
Term
what is the first marker to appear in Hep B infection
Definition
HBsAg Hep B surface antigen
Term
which marker implies immunity from Hep b infection e.g. immunisation?
Definition
anti-HBs
Term
Anti-HBs in serology implies?
Definition
vaccination/immunity against hep B
Term
in Hep B which serology result implies active infection with Hep B?
Definition
HBeAg
Term
complications of Hep B
Definition
chronic Hep b
fulminant liver failure
polyarteritis nodosa
hepatocellular carcinoma
glomerulonepritis
cryoglobulinaemia
Term
medical mx of Hep b?
Definition
antiviral (pegylated interferon alpha)
Term
skin manifestation from Hep C especially if concomitant alcoholic or IVDU?
Definition
porphyria cutanea tarda
Term
complications of hep c
Definition
chronic disease 80-90%
HCC
cirrhosis
CRYOGLOBULINEAMIA
porphyria cutanea tarda
Term
chronic disease in Hep B versus Hep C
Definition
more people have chronic hep c than Hep b
Term
treatment for Hep C
Definition
PEGYLATED INTERFERON ALPHA
RIBAVIRIN
protease inhibitor -boceprevir
Term
ribavirin
boceprevir and pegylated interferon alpha would be used to treat which viral infection?
Definition
Hepatitis C
Term
risk factors for ischemic stroke?
Definition
age
smoking
htn
diabetes
carotid artery disease
hyperlipideamia
AF
Term
Left homonymous hemianopia with macular sparing, where is the lesion?
Definition
Right posterior cerebral artery
Term
absolute CI to thrombolysis following ischemic stroke?
Definition
previous hemorrhagic stroke
stroke tia in last 6 motnhs
active bleeding
unconscious
cerebral neoplasm
Term
relative CI to thrombolysis following ischemic stroke?
Definition
known bleeding disorders
pregnancy
anticoagulant therapy
Term
secondary prevention following stroke?
Definition
Clopidogrel
anti hypertensive if HTN
statin
Term
sodium valproate is used in epilepsy, name another condition it is used in?
Definition
Bipolar disorder
Term
SE of sodium valproate?
Definition
alopecia: regrowth may be curly
increased appetite and weight gain
GI: nausea
tremor
hepatitis
pancreatitis
Term
in established epilepsy how long do you need to be seizure free before you can drive?
Definition
12 months
Term
features of migraine
Definition
unilateral
pulsatile quality
4-72 hours duration
aggravated by normal physical activity
photoboia or phonophobia
aura
nausea or vomiting
Term
common triggers for migraine?
Definition
stress
foods
dehydration
menstrual cycle in women
strong smell
bright light
Term
how to manage acute migraine attack providing there are no contraindications?
Definition
NSAIDs
oral triptan eg sumatriptan
Term
clinical features of parkinsons disease
Definition
bradykinesia
tremor
drooling saliva
rigidity
micrographia
depression
Term
complications of parkinsons disease?
Definition
falls, immobility
slowness
dementia
depression/psychosis
Term
MOA carbergoline?
Definition
dopamine receptor agonist
Term
MOA Selegiline
Definition
MAO-B inhibitor
Term
MOA procyclidine
Definition
antimuscarinic
Term
name 3 drugs that can cause drug induced parkinsonism
Definition
metoclopromide
Haloperidol
procholpromazine
Term
hand signs in RA
Definition
swan neck deformity
Boutonniere deformity
swelling
z shaped thumb
ulnar deviation
positive MCP squeeze test
Term
extra articular manifestations of RA
Definition
pericarditis
pulmonary effusions
keratoconjunctivitis sicca
anaemia of chronic disease
IHD
carpal tunnel
palmar erythema
Term
Anti-CCP higher specificity for RA what does it stand for?
Definition
Anti cyclic citrillunited peptide antibody
Term
tests to monitor MTX
Definition
baseline CXR
FBC
LFT
UE
Term
SE of MTX
Definition
neutropenia
liver enzyme derangement
pulmonary fibrosis
steven johnsons syndrome
pericarditis
vasculitis
Term
criteria before RA can be treated with biologics?
Definition
severe disease. DAS28 score >5.1
disease has not responded to a convention combination of DMARDS
Term
CAUSES OF A GOITRE
Definition
pregnancy/puberty
thyroditis
iodine deficiency
toxic multinodular goitre
AI thyroid disease
tomours: malignant/benign
TB/sarcoid
Term
signs in Grvaes disease
Definition
fine tremor
lid lag
sinus tachycardia, AF
thyroid acropachy
pre tibial myoedema
Term
medical rx options for hyperthyroid?
Definition
for symptomatic rx: beta blocker
for high T4: carbimazole
Term
indications for surgical rx of hyperthyroid?
Definition
reocccuring graves disease despite rx
intolerant of medical rx
patient preference
large goitres
Term
complications of thyroidectomy?
Definition
bleeding
damage to recurrent laryngeal nerve
hypocalcemia if there is damage to PTH glands
late hypothyroidism
Term
causes of upper GI bleed?
Definition
duodenal ulcer
oesophageal varices
mallor weis tear
oesophagitis
oesophageal cancer
Term
signs of shock
Definition
hypotension
increased CRT
tachycardia
oliguria
cold
Term
scoring systems used in upper GI bleed?
Definition
Glasgow-Blatchford score
Rockall score
Term
scoring system for liver cirrhosis?
Definition
Child-Pugh
Term
apart from alcohol, other causes of cirrhosis
Definition
drug: MTX
hepatitis B/C
NAFLD
haemachromatosis
wilsons disease
Term
examination features that would suggest OA of hip
Definition
antalgic gait
positive trendelenberg test
positive thomas test
reduced movement or pain on hip movement
wasting of gluteal muscle
crepitus
Term
DDX of hip pain?
Definition
inflammatory arthropathies e.g. reactive arthritis
neoplasm: metastatic cancer of femur
degenerative: lumbar spinal stenosis
drug induced:avascular necrosis of hip
neuropathic: lateral femoral cutaneous nerve entrapment
trochanteric bursitis
Term
non pharmacological treatments for OA
Definition
physiotherapy
lose weight if appropriate
strengthening exercises
walking aids and support such as insoles
heat and ice packs
Term
pharmacological treatments for OA hip
Definition
paracetamol
nsaids (+ppi)
opiates eg codeine
intra articular steroid injections
Term
general and specific complications of total hip replacement
Definition
general: infection, anaesthesia risk, post op delirium, AKI, death

specific
intraoperative: fracture of acetabulum
early: DVT/PE, fat embolism, sciatic nerve palsy
late: leg length discrepancy, dislocation
Term
component of the glasgow score for pancreatitis and interpretation

remember: PANCREAS
Definition
PaO2
Age >55
Neutrophilia >15
Calcium low
Renal urea raised
Enzymes LDH raised
Albumin low
Sugars glucose raise

> 3 criteria present within 48 hours suggests severe pancreatitis
Term
causes of acute pancreatitis?

IGETSMASHED
Definition
idiopathic
Gallstones
Ethanol
Trauma
Steroids
Mumps
Autoimmune
Scorpion sting
Hyperlipid, hypercalcium
ERCP
Drugs Mesalizine
Term
complications of acute pancreatitis?
Definition
chronic pancreatitis
pancreatic abscess
pancreatic pseudocysts
ARDS
Hypovoemia/shock
metabolic disturbances: hypocalcemia/hyperglyceamia
Term
complications of knee replacement
general and specific
Definition
general: infection, GA risk, post op pyrexia,pain, N&V, death

specific
intraoperative: fracture tibia
early:vascular damage, PE/DVT, fat embolism, perineal nerve palsy
late: infection, loosening, patellar instability
Term
complications of receiving a blood transfusion. these can be divided into immune mediated and non immune mediated.
Definition
non immune mediated:
infection
hyperkalemia
congestive cardiac failure

immune mediated
ABO incompatibility
heamolysis
urticaria
pyrexia
Term
causes of post operative pyrexia

remember 7 Cs
Definition
chest-pnuemonia
catheter- UTI
CVP - infection
cannula - thrombophlebitis
Cut - wound infection
Collection - abscess
Calves - DVT
Term
Wells score of 3 for ?DVT rx?
Definition
start LMWH and warfarin
Term
risk factors for developing breast cancer
Definition
BRCA genes
1st degree premenopausal family member with breast cancer
COCP
nulliparity
ionising radiation
Term
NHS breast screening programme runs for which ages?
Definition
age 47 - 73
Term
what 3 examinations occur in one stop clinic?
Definition
breast examination
mammorgraphy/USS
FNA/biopsy
Term
which is the most common type of breast cancer?
Definition
invasive ductal carcinoma
Term
side effects of tamoxifen
Definition
hot flushes
nausea
increased risk for endometrial cancer
mood swings
cerebrovascular events
thromboembolic event
eye disorders: cataracts, blurring
Term
premenopausal women with oestrogen receptor positive breast cancer are offered tamoxifen. what are post menopausal women offered?
Definition
aromataze inhibitor
Term
MOA tamoxifen?
Definition
mixed agonist antagonist of oestrogen
Term
HER2 positive breast cancer. what can be offered?
Definition
Herceptin/trastuzumab
Term
what is the difference between a direct and an indirect inguinal hernia?
Definition
direct hernia:
due to a weakness in the posterior wall of the transversals fascia. the hernia protrudes through hesselback triange medial to the inferior epigastric artery, it doesnt go down to the sctrotum.

indirect hernia
these usually stop at the superficial ring. they do not emerge in heselbachs triangle. they are lateral to the inferior epigastric artery.
Term
which anatomical structure can be used to differentiate between direct /indirect hernias?
Definition
the epigastric artery
Term
which layers do you need to cut through to get to the inguinal canal?
Definition
skin
campers fascia
scarpas faschia
external oblique aponeurosis
Term
which structure forms the floor of the inguinal canal?
Definition
the inguinal ligament
Term
name an early and late complication to do with inguinal hernia repair
Definition
early
infection
numbness
bruising
death

Late
reoccurrence
chronic pain
infertility
Term
what makes up the borders of Hesselbachs triangle?
remember RIP
Definition
medial: rectal sheath linea semilunaris
superolateral: Inferior epigastric artery
inferior: Popuparts ligament aka inguinal ligament
Term
in lap cholecystectomy why do we need to locate Calots triangle?
Definition
to find and ligate the cystic artery
Term
apart from acute cholecystitis name some other conditions caused by gallstones
Definition
pancreatitis
ascending cholangitis
gallstone illeus
billiary coli
Mirrizi syndrome
Term
risk factors for developing Gallstones?
Definition
obese
increasing age
female sex
crohns
diabetes melitus
smoking
Term
in lap chile you need to find and ligate the cystic artery. this lie in Calots triangle. what are the borders that make this triangle up?
Definition
Inferior: cystic duct
medial: common hepatic artery
superior: visceral surface of liver

Cici! cystic duct, common hepatic artery
Term
specific complications of lap cholecystectomy?
Definition
Infection
biliary leak causing peritonitis
bleeding from cystic or hepatic artery
bile duct injury
Term
the most common composition for a renal stone is?
Definition
calcium oxalate
Term
mx options for 1cm stone in ureter?

stone < 5mm can pass expectantly
Definition
shock wave lithotripsy
percutaneous nephrolithotomy
open surgery
Term
GP wants to exclude common risk factors for irate stones. what should he check levels in the blood?
Definition
calcium
phosphate
urate
Term
causes of raised PSA other than prostate cancer?
Definition
BPH
prostatitis
UTI
ejaculation
vigourous exercise
instrumentation of urinary tract
Term
unexplained symptoms where prostate cancer should be suspected
Definition
lower back pain
bone pain
erectile dysfunction
heamaturia
weight loss
Term
most common type of prostate cancer?
Definition
adenocarcinoma 95% of the time
Term
mx options for prostate cancer?
Definition
radiotherapy
surgery: radical prostatectomy
hormonal therapy
Term
which ix are used to diagnose peripheral artery disease?
Definition
ABPI
Duplex USS
Term
conservative mx of peripheral artery disease
Definition
smoking cessation
diet
exercise
weight loss
Term
what 2 drugs should someone diagnosed with peripheral artery disease be taking?
Definition
clopidogrel
statin
Term
rx options for pts with severe peripheral artery disease or critical limb ischemia
Definition
bypass
angioplasty
amputation
Term
signs of acutely ischemic limb
Definition
pale
pain
paraesthesia
pulseless
paralysis
cold
Term
which part of the colon are colorectal cancers most often found?
Definition
the rectum (40%)
Term
which areas does CRC commonly metastasise to?
Definition
liver
lung
peritoneal
brain
bone
Term
SE of stoma formation

FOUL SHITS
Definition
fluid loss
odour
ulceration
leakage
stenosis
herniation
ischeamia
terminal ileum loss
sexual and psychological problems
Term
CEA
Definition
carcinoembryonic antigen
Term
ix that occur in the 28 week antenatal visit
Definition
BP
urine dipstick
fundal height
FBC
Term
risk factors for developing pre eclampsia
Definition
age > 40
nulliparity or new partner
previous history of pre eclampsia
obesity
twins
fhx of pre eclampsia
pre existing vascular disease such as HTN or renal disease
diabetes melitis
Term
potential maternal complications of pre eclampsia
Definition
eclamsia
dic
death
HELLP syndrome
acute renal failure
Term
complications to fetus due to pre eclamsia
Definition
IUGR
feral bradycardia
respiratory distress syndrome
intracranial hemorrhage
Term
what ix occurs in a normal booking visit?
Definition
BP
urine
BMI
FBC, blood group, rhesus status
Hep B, syphillis, HIV
urine culture
Term
risk factors for developing gestational diabetes?
Definition
BMI >30
previous gestational diabetes
large baby >4.5kg
1st degree relative with diabetes
Family origin with high prevalence of diabetes
Term
diagnostic threshold for gestational diabetes?
Definition
fasting > 5.6
2 hour > 7.8
Term
mx for gestational diabetes
Definition
joint diabetes antenatal clinic
dietary advise
exercise advice
metformin
insulin
Term
examination findings that support a diagnosis of bronchiolitis
Definition
nasal flaring
tracheal tug
intercostal recession
pyrexia
inspiratory crackles
expiratory wheeze
increase HR increased RR
Term
what signs would make you send a 6 month old baby with bronchiolitis to hospital?
Definition
RR >70
Feeding < 50% normal
dehydration
central cyanosis
apnoea
o2 sats persistently <92% on air
Term
what is the name of the prophylactic monoclonal antibody you can receive for bronchiolitis?
Definition
Pavalizumab
Term
which receptor does cystic fibrosis affect?
Definition
cystic fibrosis transmembrane conductance regulator gene
Term
organisms that can colonise people with CF
Definition
staphloccocus aureus
psuedomonas aeringosa
burkholdeira cepacia
Aspergillus
Term
which tests can be used to ix a child with potential CF?
Definition
sweat test
genetic test
stool analysis
Term
mx for CF
Definition
multidisciplinary team care
chest physio
postural drainage
high calorie diet
fat soluble vitamin supplementation
pancreatic enzyme supplementation
bronchodilators
heart lung transplant
Term
which dopamine receptor do antipsychotics primarily antagonise?
Definition
D2
Term
oral morphine to sc morphine
Definition
divide by 2
Term
oral morphone to sc diamorphine
Definition
divide by 3
Term
just incase drugs
Definition
analgesia (morphine)
sedation (midazolam)
secretions (hyoscine butylbromide or glycopyronium)
antiemetic (cyclizine)
Term
which areas of the body does eczema primarily affect?
Definition
face
scalp
extensor surfaces of limbs
Term
complications of eczema
Definition
infection: with staphy aureus
psychosocial: bullying, reduce self confidence, days off school
Term
mx of eczema flare ups
Definition
emolient and topical steroid
Term
class of drug to rx itchiness associated with eczema?
Definition
antihistamine
Term
symptoms of eczema herpeticum
Definition
rapidly worsening eczema
painful eczema with blisters
punched out erosions
possible fever
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