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Kin2500 chapter 11
BLOOD
270
Biology
Undergraduate 2
03/25/2013

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Term
What are the three components of the cardiovascular system?
Definition
Blood, Blood vessels, and the heart
Term
What are the functions of the blood?
Definition
Transportation, Regulation, and Protection
Term
What does blood transport?
Definition
Metabolic waste, nutrients, hormones, and oxygen
Term
What does blood regulate?
Definition
the PH of our body, and the temperature
Term
What does blood protect against?
Definition
The excessive loss of blood, and disease
Term
The level of the number of red blood cells that you have in your body; percentage
Definition
Hemocrit
Term
What are the two components that blood is composed of?
Definition
Blood plasma 55% and Formed Elements 45%
Term
Describe blood?
How much of our body weight is it?
Definition
More dense/viscous than water
100.4 F temperature
slightly alkaline
8% of total body weight
Term
What is the blood volume in an average male and female?
Definition
Male 5-6 liters (1.5 gal)
Female 5 liters (1.2 gal)
Term
How much of plasma is made up of water and how much of solutes?
Definition
91.5 water 8.5% solutes
Term
What are the plasma solutes called and what do they do?
Definition
Plasma proteins and they are in synthesized in the liver by HEPATOCYTES (albumins, globulins, and fibrinogens)
Term
Blood cells that develop into plasma cells that produce gamma globulins which are what?
Definition
An important type of globulin; called antibodies or immunoglobulins
Term
Plasma protein that maintains bloods osmotic pressure and regulates PH
Definition
Albumins
Term
Plasma protein that binds to an antigen which will then form an antibody/antigen complex
Definition
Antibody (immunoglobulin)
Term
Plasma protein that is involved in blood clotting
Definition
Fibrinogen
Term
Explain the four steps of blood clotting
Definition
1) Bleeding starts a chemical reaction within Prothrombin activators
2) Catalytic reaction then produces thrombin
3) Thrombin then produces fibrinogen
4) Fibrinogen then lies down fibrin fibers
Term
What are the Formed Elements in blood?
Definition
RBC
WBC
Platelets
Term
What are the types of leukocytes?
Definition
Granular- neutrophils, eosinophils, basophils
Agranular- t/b cells and NK cells and monocytes
Term
What happens when someone has hypoxia (deficiency of o in the kidneys)
Definition
Leads to a stimulus of erythropoietin by kidneys to stimulate RBC production
Term
What is important for the production of RBC
Definition
arithroproiten
Term
Found in the liver; used for blood clotting
Definition
Platelets (thrombocytes)
Term
Reduced O carrying capacity of blood; not enough RBC
Definition
Anemia
Term
An overproduction of RBC; hematocrit about 54%
Definition
Polycythemia
Term
To test for blood
Definition
Media Cubital vein
Newborns- form the heel
denapuncture- the process of taking blood
Term
Checks and balances system for blood flow; regulates the number of RBC and platelets
Definition
Negative Feedback
Term
Process by which formed elements of blood are developed; first occurs in the yolk sac of embryo at conception; then permanently in the RBM
Definition
Hemopoiesis
Term
With the exception of ______, Formed Elements do not divide once they leave the Red Bone Marrow
Definition
Lymphocytes
Term
.05-1% of RBM cells derived from mesenchyme capacity to develop into many types of cells
Definition
Pluripotent stem cells
Term
Completes its development in the RBM; they are progenitor cells that are not capable of reproduction and committed to giving rise to more specific elements of blood
Definition
Myeloid stem cells
Term
Start in the RBM but complete development in the lymphatic system
Definition
Lymphoid stem cells
Term
Injects its nucleus and becomes a reticulocyte that carries oxygen; contains hemoglobin; 2 million per second rate of production of RBC in humans
Definition
Proerythroblast
Term
What is the production of RBC
Definition
Erythropoesis
Term
A cell near the end of its developments sequence that ejects its nucleus
Definition
Reticulocyte
Term
No nucleus or organelles, contains 280 million hemoglobin molecules
Definition
RBC
Term
Made up of four polypeptide chains and 1 iron on each chain and at the center of each heme ring is an iron ion
Definition
Globin
Term
What happens when oxygen and iron combine?
Definition
It forms a reversible reaction
Term
What is the shape of RBC
Definition
Bioconcave, lacks nucleus, and has spectrin to make it plyable
each one can carry four o molecules
Term
Oxygen carrying capacity of blood is reduced; not enough rbc
Definition
Anemia
Term
The lack of absorption of iron
Definition
iron deficiency anemia
Term
The lack of absorption of B12
Definition
Pernicious anemia
Term
The loss of blood due to bleeding
Definition
Hemorrhagic anemia
Term
Defect in the cell membrane causing it to rupture
Definition
Hemolytic anemia
Term
Hereditary, causes a deficiency in hemoglobin
Definition
Thalassemia
Term
Destruction of bone marrow
Definition
Aplastic Anemia
Term
RBC looks like a sickle; can rupture easily; causes anemia and blood clots
Definition
Sickle-cell disease
Term
What is the life cycle of a RBC?
Definition
About 120 days they are removed by phagocytic macrophages after they rupture; they occur in the spleen and liver where the products are recycled
Term
What is the production of RBC that occurs in the red bone marrow with precursors called proerythroblast and ejects its nucleus to become a reticulocyte
Definition
Erythropoiesis
Term
What does it mean that RBC are mitotic?
Definition
They cannot replicate
Term
More than 100 types of genetically determined antigens have been detected. What are the two blood grouping systems?
Definition
Rh grouping and ABO
Term
All leukocytes stem from myeloid cells except for what?
Definition
Lymphocytes
Term
What are the granular leukocytes?
Definition
Eosinophil, neutrophil, basophil
Term
what are the agranular leukocytes?
Definition
Monocytes and lymphocytes
Term
Which granular leukocyte releases histamines, which slow down the inflammation caused by allergies; attack parasitic worms; use phagocytosis to destroy antigen-antibody complexes
Definition
Eosinophil
Term
Which granular leukocyte involved in the inflammation and allergy reaction; leave the capillaries and enter something as a mast cell; releases the histamines; release heparin (blood thinner) and release serotonin (hormone that relaxes you) and histamine
Definition
Basophil
Term
Which granular leukocyte The fastest of all the white blood cells in response to bacteria; direct action against it; high neutrophil count in pus; release lysosomes (have a bleaching agent; can destroy bacteria)
Definition
Neutrophil
Term
WBC and other nucleated body cells have proteins, called major histocompatibility (MHC) antigens, protruding from their plasma membranes into the extracellular fluid
Definition
Agranular leukocytes
Term
Which agranular leukocytes migrates to blood tissue where they enlarge and become macrophages
Definition
Monocytes
Term
Which macrophages go exactly to the site they need to go to and adhere to the epithelial tissue?
Definition
Fixed Macrophages
Term
Which macrophages go wherever and when they eventually wind up where they are needed
Definition
Wandering Macrophages
Term
Protrude from the cell membrane; everyone has an exact pair except for identical twins
Definition
Histocompatibility
Term
What is the general function of WBC ?
Definition
To combat pathogens by phagocytosis or immune responses
Term
Which WBC are continually being recycled?
Definition
Lymphocytes
Term
Once they leave the blood and go to the site of infection they dont ever return
Definition
Granular leukocytes and monocytes(agranular)
Term
Process by which WBC cross capillary walls to get the site of infection; WBC roll along the endothelium lining of capillaries and squeeze their way out of the lining to where they need to go
Definition
Emigration
Term
Once at site, WBC; neutrophils and macrophages are active in phagocytosis
Definition
Phagocytosis "phagocyte"
Term
Process by which chemicals are released by microbes, once released they detract a defense system of chemotaxins; when a WBC attacks a toxin
Definition
Chemotaxis
Term
A bleaching agent that is going to help cure/ fight the infection; release a bleaching agent to fight some microbes and they are toxins
Definition
Lysosomes
Term
Major combatant in immune systems- B, T, and Natural T killer cells
Definition
Lymphocytes
Term
Which lymphocytes develop into plasma cells; destroy bacteria and their toxins
Definition
B cells
Term
Which lymphocytes attack some fungi, viruses, transplanted organs, and some cancer
Definition
T cells
Term
Which lymphocytes attack many microbes and tumor cells and continually move among the lymphoid tissues, lymph, and blood
Definition
Natural Killer
Term
Agranular- gets to site of infection (like neutrophils but slower) they bring the army and come in large numbers when they get to the site. There are two types
Definition
Monocytes
Term
What are the agranular monocytes that are like little nomads they just wonder and wait until they are needed?
Definition
Wondering macrophages
Term
What are the agranular monocytes that adhere to the wall of whatever tissue needs to be cured
Definition
Fixed Macrophages
Term
What do WBC have; meaning that they are ID markers on cell membranes and they extend into the plasma/extracellular fluid (everyone has their own. this was used in a murder case)
Definition
MHC (major histocompatibility)
Term
Takes longer to get to the site of infections than do neutrophils; differentiate into wondering and fixed macrophages
Definition
Monocytes
Term
Leave the tissue and release heparin, serotonin, and histamine
Definition
Basophils (granular)
Term
Releases histamines, which slow down the inflammation caused by allergies; attack parasitic works; use phagocytosis to destroy anti-antogen complexes also phagocytize antigen–antibody complexes
Definition
Eosinophil (granular)
Term
Comes on quickly, more common in young children. develops almost immediately at any age; uncontrolled production of immature leukocytes; they get so large in number they start to squeeze out RBCs and platelets. most common form of this cancerous form of leukemia
Definition
Acute leukemia
Term
later in life; RBCs accumulate in the blood stream and don’t die; either characterized by lymphocytic(more lymphocytes) or monocytic(more monocytes) and depends on the prevalent number in the blood stream
Definition
Chronic leukemia
Term
What are thrombocytes?
Definition
Platelets
Term
What do platelets do?
Definition
Help stop blood loss from damaged blood vessels by coming together to form a platelet plug that fills the gap in the blood vessel wall
Term
What do platelets initiate?
Definition
series of chemical reactions that culminates in the formation of a network of insoluble protein threads called fibrin
Term
Fragments essential to blood clotting; fills in the gap where they are needed in a blood clot that are stored in the liver
Definition
Platelets
Term
Thrombocytopenia
Definition
inability to produce enough platelets (treatment is steroid treatment to boost the platelet level)
Term
What happens when a cut occurs?
Definition
releases prothrombin activators – prothrombin is produced by the activators – prothrombin catalyzes the conversion of prothrombin to thrombin – thrombin leads to fibrinogen which then makes the fibrin fibers
Term
How long do platelets live?
Definition
five to nine days in the blood stream and they are formed in the bone marrow then they are taken out by macrophages which is done in the liver and spleen
Term
Blood thinners to prevent blood clothes and prevent strokes
Definition
Anticoagulents; Heprin and coumadin
Term
What is in the blood that makes it flexible?
Definition
Spectrin
Term
What is an inherited deficiency in blood clotting factors? causes spontaneous bleeding and very dangerous
Definition
Hemophilia
Term
Most common type- its males only and they have inherited a problem with factor number 8
Definition
A
Term
Lacks the intrinsic factor number 9- males only
Definition
B
Term
Males and females; less severe of the three because it allowsan alternate clotting factor to take place; there is treatment
Definition
C
Term
Replacement of cancerous or abnormal red bone marrow with healthy red bone marrow; establishes normal blood cell counts
Definition
Bone marrow
Term
Like a stem cell transplant bc the stem cells can live ab six months before they mature into anything (donated umbilical cords) removal of stem cells from the umbilical cord/placenta
Definition
Cord blood
Term
The study of the heart and the diseases associated with it
Definition
Cardiology
Term
How many times a day does the heart beat?
Definition
100,000 times
35 million a year
Term
Hollow, cone-shaped, and the size of a closed fist
Definition
Heart
Term
Where is the heart located?
Definition
In the Mediastinum cavity; from the first rib to the diaphragm and btwn the coverings (pleura) of the lungs
Term
Where does the majority (2/3) of the heart lie?
Definition
To the left of the midline
Term
The bottom of the heart
Definition
Apex
Term
Superior to the apex
Definition
Base
Term
The outlines shape of an organ on the surface of the body
Definition
Term
What contains the pericardial fluid between the parietal and visceral layers. if it is related to the heart wall then its called the epicardium; if its to the pericardium it is called the visceral serous membrane
Definition
Pericardial Cavity
Term
Membrane sac that surrounds the heart and is made up of two layers
Definition
Pericardium
Term
The more superficial of the two layers of the pericardium; tough and inelastic dense irregular connective tissues; anchors the heart in place
Definition
Fibrous
Term
The deeper of the two layers of the pericardium; consists of two layers(parietal and visceral)
Definition
Serous
Term
Serous membrane; ____fused with the pericardium and _____ that surrounds the heart itself
Definition
Parietal layer
Visceral layer
Term
What are the three layers of the heart wall?
Definition
Epicardium, myocardium, and endocardium
Term
3 layers of heart wall; The same thing as the visceral layer of the pericardium (epicardium is a term used when talking about the heart wall)
Definition
Epicardium
Term
3 layers of heart wall; Cardiac muscle tissue responsible for pumping action of the heart
Definition
Myocardium
Term
3 layers of heart wall; Continuous with the endothelium of the blood vessels; provides smooth lining for chambers of the heart and covers the valves
Definition
Endocardium
Term
Connect ends of neighboring cardiac muscle fibers
Definition
Intercalated discs
Term
Hold the fibers together
Definition
Desmosomes
Term
Allow muscle action potentials to conduct from one muscle to the other
Definition
Gap junctions
Term
What are the four chambers of the heart?
Definition
2 Atria and 2 Ventricles
Term
What are the two superior receiving chambers of the heart?
Definition
Left and Right atrium
Term
There to allow increase in blood volume in the atrium a space that allows the heart itself to increase in blood volume
Definition
Auricles
Term
What are the two inferior pumping chambers?
Definition
Left and Right ventricles
Term
The right side of the heart; weaker; moves deoxygenated blood to the lungs right atrium and right ventricle moves deoxygenated blood through the lungs
Definition
Pulmonary Pump
Term
The left side of the heart; stronger; pumps oxygenated blood to all the systems of our body left atrium and left ventricle, pump oxygenated blood out into all the systems of our body
Definition
Systemic Pump
Term
Marks line on the external boundaries between right and left ventricles
Definition
Coronary sulcus
Term
What contains coronary blood vessels and variable amounts of fat; each marks external boundaries between the two chambers of the heart
Definition
Sulci
Term
Makes the boundary between the right and left ventricles; on anterior side of heart.
Definition
Anterior Interventricular sulcus
Term
Marks boundary between left and right ventricles on the posterior side of heart
Definition
Posterior interventricular sulcus
Term
Which chamber receives deoxygenated blood from three veins and takes deoxygenated blood into the lungs
Definition
Right atrium
Term
Dumps deoxygenated blood into the right atrium
Definition
Superior Vena Cava
Term
Dumps deoxygenated blood into the right atrium
Definition
Inferior Vena Cava
Term
Lies in the coronary sulcus; pushes blood into the right atrium
Definition
Coronary Sinus
Term
Pectinate muscle is only in which atria?
Definition
Right atrium
Term
Anterior wall has internal muscular ridges called what?
Definition
Pectinate muscles
Term
Separates the left and right atrium division between two atriums
Definition
Interatrial septum
Term
A remnant of foramen ovale in fetal development; an oval depression
Definition
Fossa ovalis
Term
Blood from right atrium to right ventricle has to pass through this
Definition
Tricuspid valve
Term
The blood goes from the right atrium to the right ventricle through which valve?
Definition
Tricuspid
Term
The second largest chamber in the heart? forms most of the anterior part
Definition
Right ventricle
Term
Series of ridges formed by raised bundles of raised cardiac muscle fibers
Definition
Trabeculae carneae
Term
Looks like little strings; attached to papillary muscle that opens and closes to allow blood to flow into the right ventricle; chords attached to bicuspid valve
Definition
Chordae tendineae
Term
Separates the left and right ventricles internally
Definition
Interventricular septum
Term
Blood passed through it, then the pulmonary trunk, then the lungs; goes back into the right and left pulmonary arteries that carry deoxygenated blood
Definition
Pulmonary valve
Term
Divides into left and right pulmonary arteries that carry blood back to the lungs
Definition
Pulmonary trunk
Term
remnant of the ductus arteosus; comes off the left pulmonary artery; in fetal development it shuts blood from the arteries to keep it away from the lungs (one reason that makes premature births tricky)
Definition
Ligamentum arteriosum
Term
Blood goes through the pulmonary trunk and continues through right and left pulmonary arteries that supply blood to the ____
Definition
lungs
Term
Forms the base of the heart and receives oxygenated blood from the lungs via four pulmonary veins and now it flows to the bicuspid valve
Definition
Left Atrium
Term
Where do the pulmonary veins come from?
Definition
Two from each lung
Term
Whats another name for the bicuspid mitral valve?
Definition
left atrioventricular valve
Term
LAMB
Definition
Left atrioventricular valve, mitral valve, bicuspid
Term
what happens in a mitral valve prolapse?
Definition
if bicuspid doesn't close all the way a seepage will regurgitate blood back into the left atrium
Term
Blood passes from the left atrium to the left ventricle through the ____ valve
Definition
bicuspid
Term
Condition where the blood enters into the left ventricle and there is a regurgitation of blood back up the bicuspid valve
Definition
microvalve prolapse
Term
Where does blood go after the left ventricle?
Definition
ascending aorta through the aorta valve
Term
Thinner, delivers blood under less pressure
Definition
Atrium
Term
Thicker because it delivers blood at high pressures. Left especially because of the higher pressure and the blood has to go further
Definition
ventricles
Term
There are four valves that prevent backflow of blood in the heart after blood passes through them; what are they?
Definition
Tricuspid, bicuspid, aortic, and pulmonary
Term
Located between the atrium and the ventricles
Definition
Atrioventricular (bicuspid and tricuspid)
Term
The bicuspid and tricuspid valve open using what?? by contractions of the papillary muscle
Definition
Chordae tendineae
Term
What are the two semilunar valves that allow ejection of blood from the ventricles and prevent backflow of blood into the heart?Constructed similarly with simple folds
Definition
Pulmonary and Aortic valve
Term
The heart pumps blood into two circuits arranged in a series (connected end to end) what are the two ways?
Definition
Systemic and pulmonary circulation
Term
Left side of the heart; receives red, oxygenated blood from the lungs; eject blood into the aorta which branches into progressively smaller systemic arteries that carry blood throughout the body
Definition
Systemic circulation
Term
arteries to arterioles to capillaries to venules to veins
Definition
progressively smaller
Term
Right side of the heart that receives deoxygenated blood from systematic circulation; blood flows from pulmonary trunk to the pulmonary arteries that carry blood into the lungs
Definition
Pulmonary circulation
Term
What are the two coronary arteries?
Definition
Left and Right coronary arteries
Term
Composed of anterior interventricular and cicumflex branch?
Definition
Left Coronary Artery
Term
Composed of Posterior interventricular and Marginal Branch?
Definition
Right Coronary Artery
Term
The LCA and RCA branch from what? and provide the heart with the blood that it needs; supplies the myocardium with blood
Definition
The ascending aorta
Term
Supplies both ventricles with blood
Definition
Anterior interventricular
Term
Supplies the left atrium and the left ventricle with blood
Definition
Circumflex branch
Term
Supplies both ventricles with blood
Definition
Posterior interventricular
Term
Supplies the right atrium and the right ventricle with blood
Definition
Marginal branch
Term
Collateral way to get blood; almost all blood vessels have an _____ alternate route to get blood
Definition
Anastomoses
Term
Dumps blood into the right atrium; in the coronary sulcus
Definition
Coronary sinus
Term
Characteristic of coronary muscle
Definition
Autorythmic Cells
Term
Fixes irregular heartbeat
Definition
Pacemaker
Term
looks for irregular heartbeat
Definition
EKG
Term
P wave
Definition
Atrial polarization
Term
P-Q interval
Definition
The time it takes form the action potential to get from the atria to the ventricles
Term
Q-R-S complex
Definition
Spread of action potential to the ventricles; ventricle depolarization
Term
T wave
Definition
Ventricular polarization
Term
Blood protects against what?
Definition
Excessive loss, injury, and disease
Term
Site of hemopyosis in the adult includes all of the following except
Definition
the liver
Term
The heme portion of hemoglobin contains iron that binds reversibly with oxygen, in addition to oxygen and carbon disoxide transport what does hemoglobin do?
Definition
Functions in blood pressure regulation by faring nitric oxide throughout the body
Term
What is the life span of a RBC
Definition
Four months
Term
What leads to an increase in RBC production?
Definition
Hypoxia, test, and erythropoeitin
Term
Monocytes migrate into body tissues to become phagocytic cells called what?
Definition
Macrophages
Term
Neutrophils provide weapons against bacteria in the form of ?
Definition
Lysosomes, defensins, oxidants
Term
The white blood cells that typically increase in number in response to allergic conditions or parasitic infections are
Definition
Eosinophil
Term
What do platelets do?
Definition
Promote blood clotting
Term
Hematocrit of 65% or higher is an indication of what?
Definition
Polycythemia
Term
What are the moelcules that are the most abundanta and the smallest of the plasma proteins are the
Definition
Albumins
Term
The process of RBC formation is called
Definition
Hemopoeisis
Term
Fixed macrophages and which two organs remove the worn out RBC and platelets from the blood stream
Definition
Spleen and Liver
Term
B cells develop into ___ whose function is to ____ to inactive bacteria poisons
Definition
Plasma cells; produce antibodies
Term
The WBC that are the first to respons to tissue destruction caused by bacteria are the
Definition
Neutrophils
Term
T cells that destroy invading microbes are also called
Definition
Killer T cells
Term
What are the five main types of blood vessels?
Definition
Arteries, arterioles, capillaries, venules, and veins
Term
A small vein that collects blood from capillaries and delivers it to a vein
Definition
Venule
Term
A very small artery that delivers blood to a capillary
Definition
Arteriole
Term
Carries blood from the tissues to the heart
Definition
Vein
Term
Carries blood away from the heart
Definition
Artery
Term
What are the 3 layers of the Tunica Interna?
Definition
Basement membrane, Endothelium, and Internal Elastic Lamina
Term
What are the two layers of the Tunica Media ?
Definition
Smooth muscle and External Elastic Lamina
Term
What is the layer of the Tunica Externa ?
Definition
Dense irregular connective tissue
Term
Arteries have a high compliance what does that mean?
Definition
That they have the ability to stretch
Term
What is vasodilation
Definition
arteries increase in diameter and become larger
Term
What is vasoconstriction
Definition
Arteries decrease in diameter and become smaller
Term
What are the three types of arteries?
Definition
Elastic arteries, Muscular arteries, and Anastomoses
Term
How big are elastic arteries and what gives them a yellow tint? are the external and internal lamina well defined?
Definition
Largest in the body, elastic lamallae gives yellow tint, and yes
Term
What is the function of Elastic Arteries
Definition
They propel blood long distances, momentarily stores blood which converts mechanical energy into kinetic energy by momentarily holding blood
Term
What are some examples of Elastic Arteries
Definition
Common Carotid, Common iliacs, aorta, pulmonary trunk, brachiocephalic, subclavian
Term
How big are muscular arteries? Do they have more or less smooth muscle than elastic arteries? are the internal and external lamina both well defined?
Definition
Medium sized; more which causes them to be more capable of vasodilation/vasoconstriction; internal well defined and external very thin
Term
Why are muscular arteries called distributing arteries? and what are some examples
Definition
Bc they continue to branch; brachial and radial
Term
What does vascular tone mean?
Definition
Ability of the artery to contract and maintain a state of partial contraction
Term
What is an anastomoses?
whats its function?
Definition
An alternate route of blood flow in collateral circulation
to provide an alternate path if theres an obstruction
Term
What is collateral circulation?
Definition
ability of blood to flow through alternate routes to a body part through an anastomosis
Term
What are end arteries?
Definition
Arteries that do NOT have anastomoses
Term
What are arterioles?
Definition
Smallest of the artery group
Term
What is the terminal end of an arteriole called?
Definition
Metarterioles
Term
What do pre capillary sphincters do?
Definition
Control if blood goes to the capillary bed or if it goes through the thoroughfare channel.
Term
Why are arterioles known as resistance vessels?
Definition
Because they are going to regulate the amount of blood that goes into capillary beds
Term
What happens at the capillary bed?
Definition
Exchange of Oxygen and CO2
Term
What are the two layers of a capillary?
Definition
Endothelium and basement membrane
Term
What is the function of a capillary?
Definition
Exchange of O between blood and interstitial fluid
Term
What is a post capillary venule?
Definition
Where the blood is received after it goes through the capillary
Term
The tissues in our body that are more metabolically active have more extensive capillary beds. What are a few examples?
Definition
Skeletal muscle, smooth muscle, locations where theres alot of metabolic movement. Brain, liver, kidneys, eyes, and nervous system.
Term
What is a thoroughfare channel?
Definition
The distal end of the metarterioles; no smooth muscle provides a direct route from an arteriole to a venule bypasses the capillaries
Term
What is the blood flow through the capillary bed?
Definition
Arterioles>Metarterioles>capillary bed>post capillary venule>venule
Term
What are the three types of capillaries?
Definition
Continuous, Fenestrated, and Sinusoids
Term
Explain the structure of continuous capillaries and give examples
Definition
plasma membrane forms a continuous tube; found in any area with high activity such as the brain and the lungs
Term
Explain fenestrated capillaries and tell where they are found
Definition
Plasma membrane has small pores (little windows everywhere) and they are found in the kidneys and the small intestines
Term
Explain sinusoids vessel structure and examples
Definition
Plasma membrane is incomplete...large holes in endothelium and they are found mainly in the bone marrow
Term
What are venules?
What are their function?
Definition
Small veins
Bring blood back to the heart; drain capillary blood and start blood flow back to the heart
Term
What is the difference between the tunica interna of a vein and an artery?
Definition
Internal elastic lamina is missing
Term
What is different about the tunica media of a vein from the artery?
Definition
External Lamina is missing
Term
Are the tunica externa of the arteries different than that of the veins?
Definition
This one is going to be thinner
Term
What are the two types of circulation ?
Definition
Systemic and pulmonary
Term
Which circulation includes the left ventricle and right atrium (chambers) and it flows to all organs of the body.
Definition
Systemic
Term
What do all systemic arteries branch from?
Definition
Away from the heart and are going to be oxygenated they will all branch from the aorta
Term
Which chambers does pulmonary circulation include and what organs does the blood flow to and from?
Definition
Right ventricle and left atrium ; lungs
Term
The largest artery of the body; 4 divisions
Definition
aorta
Term
What are the four divisions ?
Definition
Ascending aorta
Arch
Thoracic
Abdominal
Term
Where does the ascending aorta start?
Definition
Aortic arch
Term
What two arteries does the ascending aorta split into?
Definition
Right coronary and left coronary
Term
What are the three main branches of the arch of the aorta?
Definition
Brachiocephalic
subclavian
common carotid
Term
What two arteries does the brachiocephalic trunk split into?
Definition
Right subclavian and right common carotid
Term
Is the left common carotid artery more medial or lateral than the left subclavian artery?
Definition
medial
Term
Name the four arteries in order
Definition
Subclavian, axillary, brachial, radial/ulnar
Term
What do the radial and ulnar arteries form when they meet in the hand?
Definition
Palmar arch
Term
The two vertebral arteries come together to form what artery?
Definition
Basilar
Term
What is the circle of willis?
Definition
Located in the brain (arrangement of arteries) arrangement of blood vessels at the base of the brain
Term
At what point do the vertebra become thoracic aorta?
Definition
T4 Vertebrae
Term
Where do the visceral branches of the thoracic aorta go?
Definition
These are going to go to your organs
Term
Where do the parietal branches of the thoracic aorta go ?
Definition
these are going to go to the walls of the body
Term
There are paired and unpaired branches of the abdominal aorta what are the two paired and what are the two unpaired?
Definition
Paired- renal and gonadal
Unpaired- splenic and common hepatic
Term
What two arteries does the abdominal aorta split into ?
Definition
Right iliac and left iliac
Term
Does the internal or external common iliac artery become the femoral artery?
Definition
External
Term
What is the femoral artery called when it is behind the knee?
Definition
Popliteal
Term
The popliteal artery splits into what two arteries?
Definition
Anterior tibial
posterior tibial
Term
Tell where the following 7 veins drain into:
1. superior sagittal sinus 2. inferior sagittal sinus 3. straight sinus 4. R transverse sinus 5. L Transverse sinus 6. R sigmoid sinus 7. L sigmoid sinus
Definition
1. right transverse sinus 2. straight sinus 3. left transverse sinus 4. right sigmoid 5. left sigmoid 6. internal jugular 7. internal jugular
Term
How many brachiocephalic veins are there? what 2 veins make up the SVC ?
Definition
2; Right brachiocephalic & Left brachiocephalic
Term
What vein does the axillary vein turn into?
Definition
subclavian
Term
What vein connects the cephalic vein to the basilica vein at the elbow?
Definition
Median cubital (this is the veins that they take blood from)
Term
What vein extends from the palmar venous plexus to the basilica vein and/or the median cubital vein?
Definition
Median antebrachial
Term
Is the cephalic vein medial or lateral to the basilic?
Definition
LAteral
Term
Is the brachial vein superficial or deep
Definition
Deep
Term
Is the great saphenous medial or lateral?
Definition
Medial
Term
The great saphenous joins with the femoral vein and then becomes what vein?
Definition
External iliac
Term
The external iliac and the internal iliac join to form what vein?
Definition
common iliac
Term
What vein leads into the IVC?
Definition
Left and right common iliac
Term
Is the small saphenous medial or lateral ?
Definition
lateral
Term
The small saphenous and the popliteal veins join to become what vein ?
Definition
Femoral
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