Term
|
Definition
Filtration
reabsoprtion
secretion |
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Term
|
Definition
| hold capillaries away from each other so that fluyid can pass easy |
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Term
|
Definition
- get rid of waste
- return good looking blood to body
- control flow
- control bp, bv
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Term
| filtrate is sim to plasma except |
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Definition
| there are no protien RBC, WBC, that get out |
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Term
| how does glomerular filtration occure |
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Definition
- Glomerular cells sit on B membrane
- Epithelium cells sit along b membrane and stand on pseudopods
- Fluid filter between pseudopod legs ( to get in blood)
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Term
| Why are pseduopods important? |
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Definition
| allows fluid to be filtered (ist filtration_) to get out of capillary |
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Term
|
Definition
Netrwork of blood vessels that surround nephrone
How reabsoprtion and secretion takes place |
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Term
|
Definition
| Return blood to body as perfect as possible |
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Term
|
Definition
| Blood enters bowmans capsule- initial formation of urine |
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Term
|
Definition
| Get rid of everything water electrolytes aminoacids return to blood |
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Term
|
Definition
Bring some back in appropriate amounts
- distal tubule
- Fine adjustment
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Term
| What does the Juxtaglomerular apparatus concists of? |
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Definition
- Maculadensa= check na content
- Juxtaglomerular cells = Check pressure
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Term
| What is the purpose of the J apparatus |
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Definition
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Term
| What is responsible for the release of renin ( starting whole RAA) |
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Definition
|
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Term
|
Definition
- Sence stretch on afferent arteriole as blood goes in
- Maculadensa check na content and pressure
- adjust GFR
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|
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Term
| When urine reaches the D- tubule (explain) |
|
Definition
- Jcells measure b/f in afferent arteriole and urine flow & comp @ the distal tubuels
- Renin released in responce to decrease pressure and increase urine sodium
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Term
|
Definition
Hypertonic
need more fluid |
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Term
| Renin Release initiates the RAA ( explain) |
|
Definition
- Renin convert angiotensinogen
- angiotension 1 (mild vasoconstrict)
- a1 hook up with ace in lungs
- create angio 2 (strong)
- release aldosterone na water reabsorbed, bv increase k+ excreted decreased k+
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Term
|
Definition
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Term
| Release of aldosterone will do what? |
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Definition
|
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Term
|
Definition
- Hypothalmus sense increase osmolality
- send message to post pituitary release ADH
- ADH make collect duct more perm
- water is reabsorbed from urine to blood
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Term
|
Definition
overstretched Atria
- to much fluid, to much preload coming back to hrt |
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Term
|
Definition
overstretched vent
decreased in stretch turns BNP off |
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Term
|
Definition
- Kidneys stop reabsorbing na, H20
- decrease bV, BP
- decrease stretch & wrk load of hrt
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|
Term
Pt with severe renal disease why?
anemia?
weak bones? |
|
Definition
o erythropoeitin
or may be undergoing hemodialysis
o vit d activation, can't absorb ca+ |
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Term
| Gold standard renal function? |
|
Definition
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Term
|
Definition
Don't sep
congenital
can be benign
can be addressed surgically |
|
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Term
| inherited kidney disorder |
|
Definition
nephrophisis
polycystic kidney disease |
|
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Term
|
Definition
childhood
distal tubular
atrophy/sclerosis
urine tubes thick sclerotic
complete renal problems |
|
|
Term
Polysytic kidney disease
(autosomal dom) |
|
Definition
assystemic-(onekidney)
associated with vasular disease
AAA or cerbral aneurysms |
|
|
Term
Polysystic kidney disease
(recessive) |
|
Definition
bilateral
other problems
lung imparment
portal HTN, liver disease increase mortality |
|
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Term
| Cystic disorders of cystine disease of kidney |
|
Definition
Fluid sac w/i tubules
- simple:- don't affect renal function
- acuired:- result from hemodialysis
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Term
|
Definition
disease of collecting ducts
sponge-like cysts
cause stasis urine/infection |
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Term
| consequences of cysttic dilation of renal tubules or tract |
|
Definition
- Hyronephrosis
- Staisis of urine
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Term
|
Definition
tissue exspand decrease bf
decrease bf=tissue ishemia= injury= inflammation process |
|
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Term
| explain obstruction renal calculi (theroies) |
|
Definition
Sat- supersat
Matric- organic
inhibitor- absence/ defic enzyme that inhibits stone formation |
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Term
|
Definition
calcium- oxlate
struvite- mag, ammonia phosphate
uric acid= gout
cystine= genetic |
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Term
|
Definition
increase fluid
diet
drugs that bind to ca+ oxalating so its not absorbed
diet change increase or decrease ph
thiazide diuretics
lithrotripsy-open removal |
|
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Term
|
Definition
Usually ascending from bladder
natural defences we have
- washout
- protective mucous
- local immune + iga
- nf
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Term
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Definition
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