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Karch Module 2 and 3
Antiinfectives and Antiinflammatory
95
Pharmacology
Undergraduate 1
01/31/2010

Additional Pharmacology Flashcards

 


 

Cards

Term
anti-infectives
Definition
used to tx infections caused by pathogens
Term
bacterialcidal and bacteriostatic
Definition
two actions of antiinfectives?
Term
broad spectrum
Definition
this means the drug is effective against several groups of organisms
Term
narrow spectrum
Definition
this means the drug is effective against a few groups
Term
-take meds as directed
-never share meds
-take with full glass of water
-expect to expect N/V/D
-may experience superinfection
Definition
what are five pt teachings for taking antiinfective drugs?
Term
-inhibit bacterial cell wall, protein synthesis, reproduction, inhibit cell metabolism and growth, disrupt microbial cell membrane
Definition
these are the mechanisms of action of antiinfectives
Term
-s/s of infection, susceptibility to infection
-c&s report
-allergies
-renal/hepatic function
Definition
for every drug, what do you want to assess?
Term
prevent spread of infection by coughing into sleeve, washing hands and good hygiene, support natural defense mechaisms
Definition
when you are trying to teach a pt how to avoid getting sick, what do you tell them?
Term
3000 ml/24 hrs, six pints
Definition
how much should one drink with any med?
Term
take around the clock, take on empty stomach, store in cool, dark dry place, take with full glass of water, report N/V/D
Definition
what are some other patient teaching things?
Term
BUN and CREAT
Definition
what labs will you look at to assess kidney function?
Term
observe for s/s of superinfection, compliance with instructions, decrease in s/s of infection, no drug allergies
Definition
what do you want to observe in patient when evaluating?
Term
binds to bacterial wall
Definition
action of penicillin?
Term
gram + bacterial infections (strep)
Definition
what are PCNs used to tx?
Term
previous hyper-sensitivities, cross sensitivities
Definition
what are some contraindications of PCN?
Term
anaphylaxis, GI VND, superinfections, seizures
Definition
what are some adverse reactions to PCN?
Term
cephalosporin
Definition
what meds are similar to PCN? and should watch for x sensitivity
Term
s/s of infection, VS, sputum, urine, WBC
-h/P for allergy
-specimen for C&S
-observable for s/s of anaphylaxis
Definition
what are some important nursing implications for PCN?
Term
discontinue immediately, admin Epiniephrine/antihistamine on hand and resuscitation eqpt available.
Definition
if a pt has an allergic reaction to PCN, what do you do?
Term
-use additional contraceptive method, take around the clock, reprot diarrhea, blood in stool, pus/mucus, no ETOH x 72 hrs.
Definition
what are some imp pt teaching incplication for PCN
Term
cephalosporins
Definition
these are widely used/distributed/concentrated in the kidney/liver
Term
cephalosporin
Definition
this drug is chemically/structurally related to PCN
Term
cephalosporin
Definition
this is used as a surgical prophylaxis
Term
cephalosporin
Definition
this is used to txx RT, skin, soft tissue, UT, brain and spinal cord
Term
tetracyclines
Definition
this is a broad spectrum abx that fights gram +/- bacteria
Term
inhibit microbial protein synthesis
Definition
action of Tetracycline
Term
renal/hepatic failure
hypersensitivity/pregnancy
Definition
contraindications for Tetracycline?
Term
dizziness, photosensitivity, blood dyscrasias
Definition
what are some adverse effects with Tetracyclines?
Term
s/s of infection (vs, wound appearance, sputum, urine, stool, WBC), obtain specimen for C&S, check renal/hepatic labs, CBC
Definition
what are nursing implications for TET
Term
causes staining of teeth, and softening of bones
Definition
why are tets not recommended for children under 8?
Term
dairy products, and no other meds within 1-3 hrs
Definition
what should the pt not consume with Tet?
Term
use non hormonal method of BC, use sunscreen lotion
Definition
what should you tell women and others in general who are on Tet?
Term
sulfonamides (bactrim and septra)
Definition
this is for tx of the holes
Term
urinary and resptory tract infections
Definition
sulfonamides tx for
Term
bacteriostatic
Definition
action of sulfanomides?
Term
hypersensitivity, renal/liver impairment, pregnancy
Definition
contraindications for sulfonamides?
Term
blood dycrasias, photosensitivity and hepatic necrosis
Definition
adverse effects of sulfonamides includes:
Term
allergies to sulfa, inspect IV site for phlebitis, monitor CBC/UA
Definition
what should you assess for when giving someone sulfanomides?
Term
sulfanamides
Definition
do not administer these via IM
Term
complete dose, use sunscreen, notify MD of S/S of superinfection
Definition
what do you need to teach with sulfanomides?
Term
fluoroquinolones (cipro/floxin)
Definition
these are synthetic drugs against gram +/- bacteria
Term
fluoroquinolones (cipro/floxin)
Definition
these work by interfering with DNA synthesis
Term
photosensitivity, hyper/hypoglycemia (idiosyncratic reaction)
Definition
adverse effects of fluoroqinolones?
Term
zn and Fe will decrease absorption, use sunscreen lotion/protection, good oral hygiene
Definition
what are some pt teaching point for fluoroquinolones?
Term
aminoglycosides
Definition
used to tx systemic infections, usually IV meds
Term
aminoglycosides
Definition
gentimicin and neomycin are both
Term
neomycin
Definition
used as a bowel prep
Term
prevent bacterial protein synthesis
Definition
how do aminoglycosides work?
Term
cuase nephro/neuro toxicity and ototoxicity
Definition
contraindications of aminoglycosides?
Term
aminoglycosdies (neomycin, gentimicin)
Definition
for this med, the peak and trough need to be adjusted
Term
trough
Definition
this is the lowest concentration of med before next dose
Term
macrolides
Definition
have an erythromycin base
Term
macrolides
Definition
this is the drug of choice for diptheria
Term
macrolides
Definition
azithromycin (zithromax) and clindamycin (cleocin) are both what?
Term
vancomycin
Definition
used in tx of life-threatening infections
Term
binds to bacterial wall causing cell death
Definition
how does vancomycin work?
Term
oto/nephrotoxicity
Definition
adverse effects of vancomycin?
Term
metrodiazole (flagyl)
Definition
used for intra abdominal, GU/integ. infections
Term
interferes with DNA synthesis
Definition
action of metrodiazole
Term
causes blood dyscrasias
Definition
contraindications with metrodiazole?
Term
seizures, dizziness, anorexia
Definition
adverse effects of metrdiazole?
Term
macrolides
Definition
when pcn cannot be given, these less toxic abx can be used
Term
Bacterialcidal, bacteriostatic, broad spectrum, narrow spectrum
Definition
Action of anti-infectives
Term
Tx of infections caused by pathogens
Definition
Anti-infectives are used for?
Term
Tx of RT, skin, soft tissue, UT, brain, spinal cord
Definition
Use of Cephalosporins?
Term
Cephalosporins
Definition
This can have cross sensitivities w PCN
Term
Cephalosporin, PCN
Definition
with these two drugs, make sure to teach the patient to use additional contraceptive method
Term
inhibit bacterial cell wall, protein synthesis, cell membrane, reproduction, metab/gluco
Definition
5 mechanisms of action for anti-infectives
Term
1. take as directed
2. never share
3. take with full glass of water on empty stomach
4. expect to exp. NVD
5. may expect yeast or fungal infection (superinfection)
Definition
5 things to teach about antibiotics
Term
s/s of infection, susceptible to infection
c&s report
allergies
renal/hepatic fnc
side effects of drugs
Definition
what is the nursing assessment for every antibiotic?
Term
prevent spread of int
handwash/hygiene
support natural defenses
take as prescribed/full course
drink 300ml of fluid
report NE allergies
take around clock at evenly spaced intervals
take on an empty stomach 1h before or 2h after
store in a cool, dark, dry place
take with full glass of water
report NVD
Definition
pt. teaching for every antibiotic
Term
BUN and CREAT
Definition
what lab values do you want to look at to assess kidney function?
Term
observe for s/s of superinfection
observe for compliance with instructions
dec. in s/s infection
no drug allergy
Definition
pt evaluation for abx
Term
previous hypersensitivity, x sensitivity
Definition
contraindication with penicillin?
Term
antibacterial, penicillin
Definition
these drugs cause anaphylaxis
Term
tetracycyline, sulfonamides, fluroquinolones
Definition
These cause photosensitivity in aBX
Term
cephalosporin
Definition
this is a surgical prophylaxis
Term
cephalosporins
Definition
chemically/structurally r/t PCN
Term
sulfunamides
Definition
you should watch this drug for allergies to sulfa
Term
cephalosprins
Definition
these are widely used/distributed/concentrated in the liver
Term
check 8th cranial nerve
Definition
bc aminoglycosides cause oto, neuro, nephro toxicity, you should
Term
sulfadiazine, sulfisoxazole, cotrimoxazole
Definition
examples of sulfanamides
Term
binds to bacterial wall-cell death
Definition
action of penicillin
Term
pfizerpen
Definition
penicillin G, Penicillin generic?
Term
discontinue, epinephrine and antihistamine on hand
Definition
if allergic reaction to pcn, then
Term
H & P
Definition
when assessing for penicillin, need to take an ______ for allergy
Term
observe for s/s of anaphylaxis
Definition
special assessment for penicillin
Term
report blood in stool, pus, mucus,
use additional contraceptive method
no alcohol x 72 hrs
Definition
for penicillin, is there any special pt teaching?
Term
aminoglycosides, macrolides
Definition
these cause oto, neuro, nephro toxicity
Term
fluoroquinolones
Definition
this is effective against anthrax and typhoid fever
Term
antacids, mineral supplements, iron salts
Definition
flouroquinolones cannot be taken with
Term
Cephalosporins
Definition
do not take fluoroquinolones with these, could cause inc. risk of CNS stimulation
Term
macrolides
Definition
this can be used as a prophylaxis for endocarditis before dental procdures in matients with valvular heart disease who are allergic to penicillin
Term
flouroquinolones
Definition
this drug will increase serum levels of digoxin if taken concurrently
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