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Jaundice
Hyperbilirubinemia in the breastfeeding infant
42
Biology
Not Applicable
05/17/2011

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Term
jaundice
Definition
clinical sign of hyperbilirubinemia 
Term
subcutaneous
Definition
just beneath the skin
Term
adipose tissues
Definition
loose connective tissues in wich fat accumulates
Term
sclera
Definition
whites of the eyes
Term
places bilirubin becomes deposited resulting in jaundice
Definition
subcutaneous (skin) and adipose (fat) tissues and the sclera (whites of eyes)
Term
onset of pathological jaundice
Definition
birth to 24 hours
Term
onset of physiologic jaundice
Definition

onset: 48-72 hours

peak: day 3-5

Term
normal physiologic jaundice bili levels
Definition
12.7-12.9 mg/dl or less
Term
% of babies with exaggerated physiologic jaundice
Definition
10% breastfed babies
Term
reasons for exaggerated physiologic jaundice
Definition

-breastfeeding not well established

-small, weak baby

-late preterm 35-37 weeks

-caloric deprivation

Term
other names for exaggerated physiologic jaundice
Definition

-Breastfeeding Associated Jaundice

-Lack of Breastfeeding Jaundice

-Starvation Jaundice

-Breastfeeding Jaundice

-Non-Breastfeeding Jaundice

Term
Onset of Breastmilk Jaundice
Definition

Onset: 5-10 days

Peak: day 15 +

Term
% of babies with Breastmilk Jaundice
Definition
1-2 % of breastfed babies
Term
amount of time a Breastmilk Jaundice baby can remain jaundice for
Definition
3-12 weeks
Term
Unconjugated bilirubin
Definition

-indirect reacting

-insoluble in water

-must be converted into conjugated form to be excreted

 

Term
conjugated bilirubin
Definition

-direct reacting

-water soluble, non-toxic

-excretable via stool

Term
incidence of jaundice
Definition

60% ft infants

80% premies

-most common physiologic problem in newborns

Term
causes of increased production/presence of bilirubin beyond what the liver can metabolize
Definition

1. Hemolysis

2. Polycythemia

3. Birth trauma with resultant bruising

Term
hemolysis and it's causes
Definition

a rapid break down of RBCs

caused by

-ABO/Rh incompatibility

-RBC disorders (spherocytosis, G6PD deficiency

Term
polycythemia and it's causes
Definition

excess RBCs

due to placenta-to-infant or twin-to-twin transfusion

Term
cephalohematoma 
Definition
a collection of blood under the scalp of a newborn; caused by pressure during birth
Term
interference with liver's capability to metabolize bilirubin
Definition

1. lack of needed enzymes caused by genetic varients/disorders of conjugation (Gilber syndrome)

2. hypothyroidism

3. genetic mutations

Term
meconium ileus
Definition

-overly thick meconium clogging intestines

-sign of cystic fibrosis

-causes poor excretion of bilirubin

Term

6 maternal factors contributing to hyperbilirubinemia

Definition

1. diabetes and hormonal disorders

2. breast abnormalities

3. breast surgury

4. retained placenta

5.hypertension/preeclampsia

6. mother-infant separation

Term
labor and delivery factors
Definition

1. epidural leading to increased use of forceps/vacuum extraction

2. birth injury or trauma with resultant bruising

Term
steps for LC approaching jaundice infant
Definition

1. quick appraisal- determine if medical intervention is immediately needed

2. History, infant, maternal, and feeding

Term
steps for quick appraisal of jaundice infant
Definition

1. lethargic

2. refusal to feed

3. excessive weight loss (> 10%)

4.vomiting

5. inadequate diaper count

6. visible jaundice in first 24 hours or extending below the shoulders at any time

Term
4 steps for assessing infant history
Definition

1. presence of risk factors (RBC disorders, hypothyroidism, genetic disorders, etc)

2. known bili level and associated risk based on AAP risk nomogram

3. color of urine and presence uric acid crystals

4. infant behavior over past 24-48 hours

 

Term

5 steps for assessing maternal history

Definition

1. underlying risk factors (diabetes, retained placenta, hypertension)

2. breast health history (surgery, anatomical abnormality)

3. evidence of breast changes (lactogenisis II)

4. breast/ nipple pain

5. evidence of MER

Term
4 steps for assessing feeding history
Definition

1. frequency of feeds

2. duration of feeds

3. swallows

4. number of voids and stools per 24hrs

Term
diaper count- first 24 hours
Definition

1 wet

1+ mec stool

Term
diaper count- day 2
Definition

2-3 wet

1+ mec stools

Term
diaper count- day 3
Definition

4-6 wet

transitional stools

Term
diaper count-day 4
Definition

4-6 wet

transitional stools

Term
diaper count- day 5
Definition

6 + wet

3-4 yellow stools

Term
evidence of dehydration
Definition

1. capillary refill longer than 2 seconds

2. poor skin turgor

3. dry mucus membranes

4. sunken fontenel

Term
physical assessment of infant
Definition

1. general apperance

2. evidence of dehydration

3. oral-facial abnormalities

4.current weight and percentage of weight loss

5. visual assessment of extent of jaundice

6. visible bruising

Term
feeding assesment
Definition

1. latch on

2. swallows

3. impact of position change

4. possibly do a test weight (>8% loss)

Term
early signs of kernicterus
Definition

-lethargy

-poor feeding

-listlessness

-loss of moro reflex

Term
late signs of kenicterus
Definition

-hearing loss

-rigid arching

-bulging fontanels

-seizures

Term
two types of bilirubin testing
Definition

1. serum (blood) bili test- heel sticks

2. TcB (trans-cutaneous bilirubin) hand held devices- non invasive

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