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Iron Metabolism
Iron metabolism
6
Physiology
Graduate
09/19/2008

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Term
Hemoglobin molecules consist of 3 components. What are they?
Definition
1) globin polypeptides
2) iron
3) porphyrin ring
Term
In general only ____% of iron intake is absorbed
Definition
10%
Term
The major carrier of iron in the blood is the ___________ molecule, which carries the ______ version of iron.
Definition
1)transferrin
2)Fe3+
Term
Iron is generally stored in ___________ or __________ molecules within the cell.
Definition
Ferritin or Hemosiderin
Term
In low iron situations, IRF (iron responsive factor) prevents____________ and ______________.
Definition
1) prevents TfR (transferrin receptor) mRNA from being degraded
2) prevents Ferritin mRNA from being translated
Term
At high intracellular iron concentrations, IRF (iron responsive factor) allows for __________ and ________.
Definition
1)allows for TfR (transferrin receptor) mRNA degradation
2) translation of ferritin mRNA (more ferritin molecules)
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