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IOS 2 Test #1
Drugs
61
Other
Graduate
03/19/2009

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Term
amphetamine
Definition
Indirectly acting Sympathometic drug (induce CCA release from sympathetic nerves), CNS action, non-polar
Term
ephedrine
Definition
indirectly acting sympathometic drug, acts directly on alpha and beta receptors, CNS action
Term
pseudoephedrine
Definition
indirectly acting sympathometic drug, acts directly on alpha receptors, CNS action.
Term
tyramine
Definition
indirectly acting sympathometic drug, MAO/COMT substrate
Term
bretylium
Definition
adrenergic neurone blocking drugs (inhibits CCA release)
Term
carbidopa
Definition
doesn't enter CNS, prevents L-dopa metabolism
Term
chlorpromazine
Definition
A1,A2,D1,D2,D3 Antagonist
Term
clonidine
Definition
A2 agoinst, antihypertensive, directly acting
Term
clorgyline
Definition
irreversible MAO-A inhbitor
Term
cocaine
Definition
A1 agonist, vasoconstrictor, hemostatis after surgery
Term
desipramine
Definition
blocks reuptake of norepinephrine.
Term
dobutamine
Definition
B1 agonist, inotropic effect(contractility) > chronotropic effect (HR), no effect on PVR
Term
dopamine
Definition
comes from tyrosine, D1, D2, A1, A2, B1 agonist. reduces blood pressure (D1, D2), decrease sympathetic in CNS
Term
entacapone
Definition
peripheral Catechol-O-methyl transferase inhibitor
Term
ephedrine
Definition
indirectly acting sympathoetic drug, Alpha and Beta directly acting, CNS action
Term
epinephrine
Definition
released by adrenal medulla, A1, A2, B1, B2 agonist, increase duration of local anesthetic by vasoconstriction. hemostatis after surgery, open angle glacoma
Term
guanethidine
Definition
adrenergic neurone blocking drugs, inhibit CCA release.
Term
imipramine
Definition
Term
isocarboxazid
Definition
MAO-A, MAO-B irreversible inhibitor
Term
isoproterenol
Definition
B1, B2 agonist
Term
metaproterenol
Definition
B2 agonist, reverses airway constriction (asthma)
Term
methoxamine
Definition
A1 agonist, stops hypotension
Term
a-methyldopa
Definition
inhibits DOPA decarboxylase, can't make dopamine
Term
metoprolol
Definition
B1 antagonist
Term
moclobemide
Definition
reversible MAO-A inhibitor
Term
norepinephrine
Definition
CCA released by sympathetic postganglionic nerves, A1, A2, B1, B3 agonist
Term
phenelzine
Definition
MAO-A, MAO-B irreversible inhibitor
Term
phentolamine
Definition
A1, A2 antagonist
Term
phenylephrine
Definition
A1 agonist, stops hypotension, nasal vasoconstriction. contracts radial muscle of iris, open eye(mydriasis)
Term
phenylpropanolamine
Definition
Indirectly acting sympathometic drug, directly acting Alpha receptor, CNS action
Term
prazosin
Definition
A1 antagonist, dialate arterioles, acts on baroceptors
Term
propranolol
Definition
B1, B2 antagonist
Term
rasagiline
Definition
MAO-B irreversible inhibitor
Term
reserpine
Definition
VMAT-2 inhibitor, prevents CCA uptake into vesicle, metabolizes CCA
Term
selegiline
Definition
MAO-B irreversible inhibitor
Term
tranylcypromine
Definition
MAO-A, MAO-B irreversible inhibitor
Term
tyramine
Definition
indirectly acting sympathometic drug, MAO/COMT substrate, present in food
Term
yohimbine
Definition
A2 antagonist
Term
acebutolol
Definition
B2 > B1 partial agonist
Term
albuterol
Definition
B2 agonist, reverses airway obstruction caused by asthma
Term
alpraclonidine
Definition
A2 agonist, decrease aqueous humor production, for open angle glaucoma
Term
bitolterol
Definition
B2 agonist, pro-drug
Term
bromocryptine
Definition
D2 agonist, D1 partial agonist
Term
carteolol
Definition
B1, B2 partial agonist
Term
cabergoline
Definition
D2 agonist
Term
dopexamine
Definition
D2, D1, B2 agonist, increases CO, increased kidney filtration
Term
fenoldopam
Definition
D1 agonist, decreases PVR and increases urine secretion
Term
guanabenz
Definition
A2 agonist, antihypertensive
Term
guanfacine
Definition
A2 agonist, antihypertensive
Term
ibopamine
Definition
D2, D1 > B2, B1 > A1, A2 agonist
Term
metaraminol
Definition
Indirectly acting agent, A agonist agent
Term
a-methylnorepinephrine
Definition
A2 agonist, made from a-methyldopa
Term
methylphenidate
Definition
indirectly acting agent, CNS stimulant (ritallin)
Term
penbuterol
Definition
B1, B2 partial agonist
Term
pergolide
Definition
D2 agonist, D1 antagonist
Term
pindolol
Definition
B1, B2 partial agonist
Term
pirbuterol
Definition
B2 agonist
Term
pramipexole
Definition
D2, D3 agonist
Term
ropinirole
Definition
D2, D3 agonist
Term
ritodrine
Definition
B2 agonist, preventing uterine contractions, delay pregnancy, SE is pulmonary edema
Term
terbutaline
Definition
B2 agonist, asthma agent, bronchodialtor, prevent uterine contractions in pregnancy, SE is pulmonary edema
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