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Introductory Animal Biology
Introductory Animal Biology Course at University of Iowa
135
Biology
Undergraduate 1
06/18/2014

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Term
What are the levels of biological organization?
Definition
Atom, Molecule, Organelle, Cell, Tissue, Organ, Organ System, Organism, Population, Community, Ecosystem, Biosphere
Term
Emergent Properties
Definition
When components interact they create new complex function. They arise from physical and chemical interactions among a system
Term
Producers (Autotrophs)
Definition
Make their own food by extracting energy and nutrients from nonliving sources ex: capture light energy from sun
Term
Consumers (Heterotrophs)
Definition
Obtain energy and nutrients by eating other organisms, dead or alive
Term
Decomposers
Definition
Heterotrophs that obtain energy and nutrients from wastes or dead organisms ex: fungi and bacteria
Term
Homeostasis
Definition
Process by which a cell or organism maintains this state of internal constancy
Term
What determines whether something is alive?
Definition
Organized, Requires Energy, Maintains Internal Constancy, Reproduces Grows and Develops, Evolves
Term
Asexual Reproduction
Definition
Genetic info comes from only one parent and offspring are virtually identical ex: flowers, bacteria, sponges
Term
Why is sexual reproduction more successful than asexual reproduction?
Definition
Because it enhances the chance that the individual will survive even if the environment changes due to genetic diversity
Term
Adaptation
Definition
Inherited characteristics that enables an organism to survive and reproduce successfully in its environment
Term
Natural Selection
Definition
Enhanced reproductive success of certain individuals from a population based on inherited characteristics
Term
Taxonomy
Definition
Biological science of naming and classifying organisms
Term
Species
Definition
Basic unit of classification that designates a "type" to organisms
Term
Genus
Definition
Closely related species
Term
What are the three domains life is classified under?
Definition
Bacteria, Archaea, Eukarya
Term
How are archaea and bacteria related?
Definition
Single-celled prokaryotes, DNA is free is the cell, NO NUCLEUS
Term
What are the four kingdoms within the domain Eukarya?
Definition
Protista (autotrophs or heterotrophs), Animalia (heterotrophs by ingestion), fungi (heterotrophs by external digestion), Plantae (autotrophs)
Term
Hypothesis
Definition
Tentative explanation for one or more observations; MUST BE TESTABLE
Term
Placebo
Definition
Inert substance that resembles the treatment given to experimental group
Term
Double-Blind Design
Definition
Neither researchers nor participants knew who received the vaccine and who received the placebo
Term
Statistical Significance
Definition
Probability that the results arose purely by chance
Term
What is the difference between a hypothesis and a theory?
Definition
Typically broader than a hypothesis, theories must be able to be proven wrong
Term
What are the four most abundant elements?
Definition
Carbon, hydrogen, oxygen and nitrogen
Term
What is the mass and charge of a proton, neutron, and electron?
Definition
Proton = Mass 1, Charge +1; Neutron = Mass 1, Charge O; Electron = Mass 1, Charge -1
Term
What does the atomic number also stand for?
Definition
The number of protons in the nucleus
Term
Ion
Definition
An atom that has gained or lost electrons and therefore has a net negative or positive charge
Term
Cation
Definition
Positively charged ions
Term
Mass Number
Definition
Total number of protons and neutrons in the nucleus
Term
Isotope
Definition
Different forms of a single element that have varying numbers of neutrons
Term
Valence Shell
Definition
Outermost occupied energy shell, atoms are most stable when their valence shells are full
Term
Covalent Bond
Definition
Two atoms share electrons, shared electrons travel around both nuclei, VERY STRONG, most bonds in biological molecules are covalent
Term
Electronegativity
Definition
Measure of an atom's ability to attract electrons, those with almost full valence shells have a high electronegativity
Term
Nonpolar Covalent Bond
Definition
Union in which both atoms exert approximately equal pull on their shared electrons, a bond between two atoms of the same element is nonpolar
Term
Polar Covalent Bond
Definition
Lopside union in which one nucleus exerts a much stronger pull on the shared electrons than does the other nucleus. Forms whenever a highly electronegative atom, like oxygen, shares electrons with a less electronegative partner such as carbon or hydrogen
Term
Ionic Bond
Definition
Results from the electrical attraction between two ions with opposite charges, form between an atom whose outermost shell is almost empty and one whose valence shell is nearly full
Term
Hydrogen Bond
Definition
Opposite partial charges on adjacent molecules - or within a large molecule - attract each other. Positive charge is always hydrogen and other is highly electronegative
Term
What are two properties of water that make it essential to life?
Definition
Cohesion and adhesion - tendency to stick together, tendency to form hydrogen bonds with substances
Term
What type of molecules do polar molecules dissolve?
Definition
Polar molecules
Term
What elements do hydrophobic molecules consist of?
Definition
Mostly carbon and hydrogen
Term
Why is water resistant to temperature changes?
Definition
Strong hydrogen bonds
Term
Acid
Definition
Chemical that adds H+ to a solution, making the concentration of H+ ions exceed the concentration of OH-
Term
Alkaline
Definition
Basic solution containing a pH greater than 7
Term
What are the four most abundant types of organic molecules?
Definition
Carbohydrates, lipids, proteins, and nucleic acids
Term
Monomer
Definition
small chains of molecular subunits ex: proteins, nucleic acids
Term
Dehydration Synthesis
Definition
Enzyme removes an OH from one molecule and a hydrogen atom from another, forming H2O and a new covalent bond between the two smaller components
Term
Hydrolysis
Definition
Enzymes use atoms from water to add a hydroxyl group to one molecule and a hydrogren atom to another, breaks covalent bonds that link monomers
Term
What elements consist of a carbohydrate and in what proportion?
Definition
Carbon, Hydrogen, Oxygen 1:2:1
Term
Monosaccharide
Definition
smallest carbohydrate, contains 5-6 carbon atoms, can have same # of carbon atoms that can different by how atoms are bonded
Term
What is a disaccharide and what is their function?
Definition
Two monosaccharides joined by dehydration synthesis, provide a ready source of energy which is released when their bonds are broken
Term
Oligosaccharides
Definition
Carbohydrates with 3-100 monomers, with a protein attached becomes a glycoprotein
Term
Polysaccharide
Definition
Complex carbohydrates, all long chains of glucose but differ by orientation of the bonds
Term
What is chitin and where is it found?
Definition
Resembles a glucose polymer but a nitrogen-containing group replaces one hydroxyl group in each monomer. Found in cell walls
Term
Why are lipids hydrophobic?
Definition
Dominated by nonpolar carbon-carbon and carbon-hydrogen bonds
Term
Triglycerides
Definition
Consists of three long hydrocarbon chains called fatty acids bonded to glycerol
Term
What is the difference between saturated and unsaturated fats?
Definition
Saturated contains all the hydrogens it can, unsatured has at least one double bonded carbon to create a kink in the fatty acid tails
Term
Trans Fat
Definition
Unsaturated fats whose fatty acid tails are straight, not kinked
Term
Sterols
Definition
Lipids that have four interconnected carbon rings
Term
Waxes
Definition
Fatty acids combined with alcohols or other hydrocarbons usually forming a stiff, water-repellent material
Term
What consists of an amino acid?
Definition
Central carbon atom bonded to four other groups; one is a hydrogen atom, one carboxyl group, amino group, and R group
Term
Peptide Bond
Definition
Forms by dehydration synthesis; covalent bonds link each amino acid to its neighbor
Term
How does the body use proteins in food?
Definition
Hydrolysis reaction breaks peptide bonds and releases amino acids from proteins in food, body uses monomers to make its own polypeptides
Term
Nucleotide
Definition
Monomer that consists of three components; center is 5-carbon sugar, ribose in RNA and deoxyribose in DNA, attached to the sugar's carbon atom is one phosphate group PO4
Term
What are the nitrogenous bases in DNA and RNA?
Definition
DNA contains A, C, G, T; RNA contains A, C, G, U
Term
What is the function of RNA?
Definition
Enable cells to use the protein-encoding information in DNA
Term
What is the Cell Theory?
Definition
All organisms made of cells, cell is fundamental unit of life, cells come from preexisting cells
Term
Phospholipid
Definition
Glycerol bonds to only two fatty acids; third carbon bonds to two fatty acids; head is hydrophilic tails are hydrophobic
Term
Selective Permeability
Definition
Hydrophobic interior of bilayer prevents ions and polar molecules from passing freely; do not block lipids and nonpolar molecules
Term
What molecule keeps the cell membrane fluid?
Definition
Cholesterol
Term
What are the five functions of proteins?
Definition
Transport molecules to pass in and out of cell, facilitate chemical reactions, recognize cells, membrane proteins enable cells to stick to one another, receptor proteins bind to molecules on a cell to trigger reaction inside cell
Term
Endomembrane systems
Definition
Nuclear envelope, endoplasmic reticulum, golgi apparatus, lysosomes, vacuoles, cell membrane; small bubbles of membrane pinch off and travel within to the cell and fuse together
Term
Nuclear Pores
Definition
Holes in the double membrane nuclear envelope. Highly specialized channels composed of dozens of types of proteins
Term
Nuclear envelope
Definition
Separates the nucleus from the cytoplasm
Term
Endoplasmic Reticulum
Definition
Network of sacs and tubules composed of membrane; originates at nuclear envelope and winds throughout the cell
Term
Rough ER
Definition
Close to nucleus membrane; studded with ribosomes making proteins that enter the inner compartment of the ER; secretes proteins
Term
Smooth ER
Definition
Synthesizes lipids; houses enzymes that detoxify drugs and poisons
Term
Golgi Apparatus
Definition
Stack of flat membrane-enclosed sacs that functions as a processing center; proteins pass through the sacs and complete their intricate folding to being functional. Manufactures and attaches carbs to proteins and lipids.
Term
Lysosomes
Definition
Contains enzymes that dismantle and recycle food particles, captured bacteria, worm-out organelles, debris
Term
Vacuoles
Definition
In plants, contains a watery solution of enzymes that degrade and recycle molecules and organelles, pH somewhat acidic
Term
Mitochondria
Definition
Organelles that use a process called cellular respiration to extract energy from food; has it's own DNA
Term
What are the five membrane functions?
Definition
1. Boundaries b/w cell and environment & b/w an organelle and cell 2. Selective Permeable 3. Intracellular transporters 4. Cell indentification, communication & adhesion 5. Location of some biochemical reactions
Term
What four things can affect rates of diffusion across the membrane?
Definition
Concentration gradient, electrical charge, temp of solution, diameter of molecules/ions
Term
What types of molecules can move easily through the phospholipid bilayer?
Definition
Small, nonpolar, uncharged
Term
If amino acid is hydrophilic is it basic or acidic?
Definition
Acidic
Term
Explain Osmosis (Jones)
Definition
Diffusion of water across a semipermeable membrane, water moves from area of high concentration to low water concentration
Term
Plasmolocist
Definition
Plant cells retract from the cell wall
Term
Facilitated diffusion
Definition
Cross a membrane via channel or carrier protein, when ligand binds to protein it changes it shape to control the permeability
Term
Active Transport
Definition
Requires energy and a carrier protein to move it across the membrane
Term
Aquaporins
Definition
Special protein channel specific for water, can allow up to 100 million h2o at one second
Term
Uniporters
Definition
Glucose transporter
Term
Antiporters
Definition
NA+/K+ pump; other ion pumps
Term
What is the difference between primary active transport and secondary active transport?
Definition
Primary uses direct hydrolysis of ATP and secondary uses energy
Term
Endocytosis
Definition
Plasma membrane surrounds the extracellular material and invaginates, forming a vesicle
Term
Exocytosis
Definition
Material in vesicles is expelled from a cell by fusion with the plasma membrane
Term
Signal transduction pathway
Definition
Sequence of molecular events and chemical reactions
Term
What side is the carboxyl group and what side is the amino acid in a protein?
Definition
Amino acid is on left, carboxyl is on right
Term
What was the first experiment done to find DNA?
Definition
Griffith, Called it the transforming principle, mouse with the dead killer virus and alive nonlethal virus
Term
How many hydrogen bonds are between A-T and C-G?
Definition
A-T = 2 hydrogen bonds, C-G = 3 hydrogen bonds
Term
What are purines and pyramidines?
Definition
Purine = Have 9 rings of carbon, A&G. Pyramidines = Have 6 rings of carbon, T&C
Term
Is DNA right handed or left handed?
Definition
Right handed
Term
What are the key functions of DNA?
Definition
Stores genetic info, susceptible to mutation, precisely replicated, expressed as a phenotype
Term
Semi-conservative model of DNA replication
Definition
Parent serves as a template and new molecules have one old and one new strand
Term
Conservative
Definition
Original helix only serves as a template for synthesis of new helix, CORRECT
Term
Dispersive
Definition
Parent fragments serve as templates assembling old and new parts into molecules
Term
Meselson & Stahl 1958
Definition
Spun DNA in a concentrated gradient to weigh the DNA after replication using N14 & N15
Term
In what direction will new DNA replicate?
Definition
5' to 3'
Term
Where does the DNA acquire power to replicate?
Definition
Triphosphate
Term
Polymerase III
Definition
Reads nucleotide and puts in correct base. Doesn't stop until it falls off or reaches a finished base
Term
Ligase
Definition
Joins Okazaki fragments and seals nicks in sugar-phosphate backbone, creates covalent bonds between bases
Term
Helicase
Definition
Protein that unwinds double helix
Term
Primase
Definition
Adds short RNA primer to template strand, can start synthesizing by putting down RNA fragments
Term
Topoisomerase
Definition
Unravels DNA ahead of helicase to release tension, like unbraiding
Term
Single stranded binding proteins
Definition
Prevents bases from breaking away and doesn't let them re-band
Term
What are the three stages in DNA replication?
Definition
Initiation, Elongation, Termination
Term
Telomerase
Definition
Enzyme that binds to open 3' end with an RNA template and adds nucleotides to elongate end & then primer comes through and readds bases
Term
What protein can bind two previously binded nucleotides?
Definition
Ligase
Term
In prokaryotic division, what are some cues for the cells to divide?
Definition
Lack of cells (bacteria) around a cell, large amounts of nutrients
Term
Cytokinesis
Definition
Pinching in the plasma membrane followed by synthesis of new cell wall materials
Term
What is the cell cycle?
Definition
Gap 1, DNA Synthesis, Gap 2, Mitosis
Term
How does the cell know to proceed with the cell cycle?
Definition
Activity of CDKS (cyclin dependent kinases), the CDKS are controlled by cyclins
Term
What is the rate of CDKS to cyclin in the cell cycle?
Definition
CDKS remains constant while cyclin varies greatly in order to initiate cycles
Term
What happens in the G1 Checkpoint?
Definition
Decision to replicate DNA, check for chromosome integrity
Term
What happens in the G2 Checkpoint?
Definition
Checks if replication is complete, checks for chromosomal damage during replication
Term
What happens in the Metaphase Checkpoint?
Definition
Checks for proper alignment of all chromosomes, checks that chromosomes are connected to both mitotic poles
Term
How are chromosomes held together in the centomere?
Definition
NOT COVALENTLY BONDED, wrapped around each other and held by proteins
Term
What are the steps in chromosomal structure?
Definition
DNA wraps around a histosome, histosomes form nucleosomes, they wrap and form chromatin
Term
What are the phases of mitosis?
Definition
Prophase, prometaphase, metphase, anaphase, telophase
Term
What occurs in prophase?
Definition
Chromosomes condense, nuclear envelope begins to breakdown
Term
What occurs in prometaphase?
Definition
Nuclear envelope disappears, chromosomes begin movement
Term
What occurs in metaphase?
Definition
Chromosomes line up on metaphase plate, mitotic spindles attach at kinetochores of each chromosome, longest phase of mitosis
Term
Kinetochores
Definition
Protein that protects centrosomes at point of attachment between spindles and DNA
Term
What occurs in anaphase?
Definition
Mitotic spindles pull, separating sister chromatid at centromere
Term
What occurs in telophase?
Definition
Chromosomes decondense, nuclear envelope reforms, cytokenesis
Term
Apoptosis
Definition
Programmed cell death, cell is no longer needed, DNA is damaged
Term
What are the steps to DNA transcription?
Definition
Initiation, Elongation, Termination
Term
Explain Initiation in DNA transcription?
Definition
Enzymes unzip the DNA double helix, exposing the template strand. RNA polymerase (enzyme that builds the RNA chain) binds to the promoter, a DNA sequence that signals the gene's start
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