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INTRODUCTION TO CELLS
BIO 311C
56
Biology
Undergraduate 1
05/11/2013

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Term
Cell Theory
Definition
all living organisms are made up of cells, the cell is the structural and functional unit of all living organisms, all cells come from pre-existing cells
Term
Common features of all cells
Definition
Plasma membrane, cytosol and cytoplasm, DNA, Ribosomes, energy and nutrient acquisition, cells are small
Term
Plasma Membrane
Definition
outer boundary of the cell
Term
Cytosol
Definition
semifluid aqueous solution
Term
Cytoplasm
Definition

everything between plasma membrane and DNA

 

Cytosol + suspended particles + organelles

Term
Ribosomes
Definition

particles made entirely of RNA and protein

 

NOT organelles

Term
Cell Size
Definition

Smaller cells are much more efficient

 

Upper limit: set by surface area to volume ratio

 

Lower limit: set by basic requirements for life

Term
SA:V
Definition

Surface area to volume ratio

 

SA = PM

V = Cytoplasm

 

as cell gets bigger, SA:V decreases

V increases faster than SA

Term
Microscopy
Definition
using microscopes by magnifying cells
Term
Light Microscopy
Definition

use visible to see cell

 

less detail but can see entire cell, larger structures inside and how it changes over time

Term
Electron Microscopy
Definition

SEM and TEM

 

a lot more detail and see smaller structures, but have to kill and preserve cells

Term
Cell Fractionation
Definition

separation and isolation of cellular contents

 

use centrifuge

Term

Prokaryotic Cells

 

Definition

Domain bacteria and archea

 

DNA not bound by nucleus

 

Do not contain membrane-bound organelles

 

Do have ribosomes

Term
Genomic Organization
Definition
1 single, circular chromosome found in nucleoid region
Term
Genome
Definition
sum total of DNA
Term
Specialized internal membranes
Definition

internal organization lacks complex compartmentalization

 

Extensions of the plasma membrane, have specialized functions

Term
Cell Wall
Definition
maintains cell shape, provides physical protection
Term
Capsule
Definition
Sticky polysaccharide or protein structure that covers cell wall, helps in protection and helps cell stick to surfaces
Term
Hair-like Appendages
Definition

stick out from cell wall and capsule, function in attachment

 

fimbriae, pili

Term
Prokaryotic Flagella
Definition
Pure protein, have a motor built into plasma membrane and cell wall which causes rotation and motility
Term
Eukaryotic Cells
Definition

larger, true nucleus, membrane-bound organelles

 

Two types:

animal cells, plant cells

Term
Animal Cells
Definition
lisosomes, centrioles
Term
Plant Cells
Definition
chloroplasts, cell wall, large vacuoles
Term
Genetic Control of Cell
Definition

store and use genetic information

 

nucleus and ribosomes

Term
Nucleus
Definition

Houses the genes in eukaryotic cells

 

DNA organized into linear chromosomes

 

Structure: enclosed by nuclear envelope, perforated nuclear pores, lined by nuclear lamina

Term
Nuclear Envelope
Definition
double memebrane (4 layers of phospholipids) that encloses the nucleus
Term
Nuclear Pore
Definition
passageways through nuclear envelope, regulate entry and exit
Term
Nuclear Lamina
Definition
lines nuclear side of envelope, maintains shape of nucleus
Term
Nucleolus
Definition
site of rRNA synthesis and ribosome subunit assembly
Term
Chromatin
Definition
DNA + protein that make up chromosomes
Term
Chromosomes
Definition
DNA
Term
Ribosomes
Definition

'particles' of rRNA and proteins that use information from DNA to build polypeptides

 

made of two subunits

Term
Free Ribosomes
Definition

floating in cytosol

 

make cytosolic proteins and proteins for non-EMS organelles

Term
Bound Ribosomes
Definition

Attached to ER or NE

 

make secreted proteins, membrane proteins, and proteins for EMS organelles

Term
Endomembrane System
Definition

Functions: production, distribution and breakdown of biomolecules

 

Structures: Nuclear envelope, ER, Golgi Apparatus, Lysosomes, Vacuoles, Plasma Membrane

Term
Endoplasmic Reticulum
Definition

Extends from NE to PM

 

Structure: cisternae, lumen

Term
Smooth Endoplasmic Reticulum
Definition

no attached ribosomes

 

Functions: synthesis of lipids, makes phospholipds and steroids, carbohydrate metabolism, calcium storage, detoxification

Term
Rough Endoplasmic Reticulum
Definition

attached ribosomes

 

Functions: protein synthesis, glycoprotein synthesis, membrane production

Term
Golgi Apparatus
Definition

the cell's receiving and shipping center

 

Structure: cisternae, polar

Cisface - receive vesicles from ER

Transface - shipping face, puts products into new vesicles

 

Functions: modifies, stores and ships products of RER, makes and ships certain macromolecules

Term
Lysosomes
Definition

animal cells

 

Structure: membranous sacs, contain hydrolytic enzymes, acidic

 

Functions: digestive compartments

Term
Vacuoles
Definition
Membrane-bound compartments with diverse functions
Term
Central Vacuole
Definition

plant cells

 

Functions: storage, disposal, contain pigments, protection, hold water

Term
Energy-Transforming Organelles
Definition

convert energy from one form to another

 

Mitochondria, chloroplasts

Term
Mitochondria
Definition

site of cellular respiration in eukaryotic cells

 

Two memebranes: outer (smooth), inner (cisternae)

 

Two compartments: intermembrane space, mitochondrial matrix

 

Contain DNA and Ribosomes

Term
Chloroplasts
Definition

site of photosynthesis in plant cells

 

contain chlorophyll (found in thylakoids)

 

Three compartments: intermembrane space, stroma (where good stuff occurs), thylakoid space

Term
Peroxisomes
Definition
specialized membrane-bound metabolic compartments that serve many different functions
Term
Cytoskeleton
Definition

network of protein fibers extending throughout the cytoplasm

 

Functions: Support, movement, regulation

 

Structure: microtubules, microfilaments, intermediate filaments

Term
Microtubules
Definition

Structure: thick, hollow tubes made of tubulin

 

Function: cell shape, vesicle and organelle movement

Term
Microfilaments
Definition

Structure: thin, solid rods made of actin

 

Functions: cell shape, cell crawling, muscle contraction

Term
Intermediate Filaments
Definition

Structure: ropelike fibers

 

Functions: support cell shape, fix organelles in place

Term
Plant Cell Wall
Definition

Structure: cellulose microfibrils embedded in a polysaccharide and protein matrix

 

Function: protection, maintenance of shape, strength

Term
Extracellular Matrix
Definition

Structure: composed of glycoproteins in a matrix of proteoglycans, attached to cells

 

Function: support, adhesion, movement, regulation of cell behavior

Term
Intercellular Junction
Definition
direct contact between cells, cell communication, adhesion
Term
Tight Junctions
Definition
press together membranes of neighboring cells, form a seal
Term
Desmosomes
Definition
connect cytoskeletons of neighboring cells, fasten cells together
Term
Gap Junctions
Definition
protein-lined channels between adjacent cells
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