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Intro to CNS+ Meninges & Cranival Vault
Week 1
82
Other
Graduate
11/29/2016

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Term
A thickened area containing the cell's nucleus and organelles. AKA soma or perikaryon
Definition
Cell body
Term
Thin, tube-like structures projecting from the soma
Definition
Neurites
Term
Project a short distance from the soma and contain protein receptors to receive signals from other neurons
Definition
Dendrites
Term
Dendritic branches of a single neuron
Definition
Dedritic tree
Term
Singular projection that may extend a great distance within the nervous system
Definition
Axon
Term
Small elevation projecting from soma
Definition
Axon hillock
Term
An uninsulated portion of the axon that is rich in voltage-gated sodium channels
Definition
Initial segment
Term
Terminal bouton/ the end of an axon
Definition
Axon terminal
Term
intracellular connections with other neurons
Definition
Synapses
Term
Small vesicles filled with chemicals within terminals
Definition
Neurotransmitters
Term
Supporting cells of the CNS and far more numerous
Definition
Glial cells
Term
What 4 things are glial cells responsible for?
Definition
1) Regulating chemicals in ECS
2) Myelinating neurons
3) Lining ventricles
4) Phagocytosis+ repair
Term
Performs complex processing of sensory information and conducts motor responses
Definition
Cerebrum
Term
Internal fluid filled spaces shown in coronal section of brain filled with CSF
Definition
Ventricles
Term
Part of cortex rich in neuronal cell bodies that give the tissue a light grey color
Definition
Gray matter
Term
Part of cortext rich in myelinated axons and are lighter colored. Collections of tracts/fasciculi
Definition
White matter
Term
Major pathway for axons crossing between cerebral hemispheres; also one of the primary white matter structures
Definition
Corpus Callosum
Term
Major pathway between cerebral hemispheres and are more caudal structures
Definition
Internal capsule
Term
Serve to increase surface area of the cerebral cortex
Definition
Gyri+ Sulci
Term
Deeper, more consistent sulci
Definition
Fissure
Term
CSF circulates out of the ventricles over the surface of the brain and spinal cord and empties into the bloodstream through
Definition
Venous sinuses
Term
Regulates and processes somatic information, sensation, and motor function. The "switchboard"
Definition
Thalamus
Term
Parts of the diencephalon
Definition
1) Thalamus
2) Hypothalamus
3) Epithalamus
4) Subthalamus
Term
Primary brain center for autonomic nervous system regulation
Definition
Hypothalamus
Term
Group of nuclei in the brain that are involved in motor processing
Definition
Basal Ganglia
Term
Associated structures of the basal ganglia
Definition
Caudate nucleus
Putamen
Globus Pallidus
Subthalamic nucleus
Substantia Nigra
Term
Located in the medial temporal lobe and is involved in memory consolidation
Definition
Hippocampal formation
Term
Consists of two hemispheres and vermis. Uses complex sensory information to unconsciously modulate motor activity.
Definition
Cerebellum
Term
The CNS interface or primitive brain. Processes sensation and some special senses. Controls somatic moor and parasympathetic (autonomic) output+ respiration, heart rate
Definition
Brainstem
Term
The rostral portion of the brain stem that controls eye movement through CN III IV
Definition
Midbrain of the brainstem
Term
Contains nuclei for communication between cerebrum and cerebellum; also nuclei for CN V, VI, VII, VIII
Definition
Pons of the brainstem
Term
Caudal portion of the brainstem. Controls consciousness, autonomic control for heart rate and breathing, and CN IX, X, XI, XII
Definition
Medulla of the brainstem
Term
Interface for CNS via peripheral nerves. Sends and receives info. via axons (tracts), that receive sensory info., modulate motor activity, modulate autonomic activity
Definition
Spinal cord
Term
Connective tissue membranes that surround the brain and spinal cord
Definition
Meninges
Term
Two layers of the dura mater
Definition
Periosteal layer- adheres to bony walls of cranium
Meningeal layer- forms "reflections" that conform more closely to the brain and divide it into cranial cavity compartments
Term
Fold that lies between the cerebrum and cerebellum in the transverse fissure; separates the cavity into supratentorial and infratentorial compartments
Definition
Tentorium Cerebelli
Term
Fold that lies within the longitudinal cerebral fissure; divides the supratentorial compartment into two halves; lies in posterior cranial fossa between cerebellar hemispheres
Definition
Falx cerebri
Term
Forms roof of hypophyseal fossa and surrounds the pituitary stalk
Definition
Diaphragm Sellae
Term
What are the main venous drainage channels for the brain?
Definition
Dural venous sinuses
Term
Attached margin of tentorium cerebelli
Definition
Transverse sinus
Term
Attached edge of falx cerebri; drains into right transverse sinus
Definition
Superior sagittal sinus
Term
Free edge of falx cerebri
Definition
Inferior sagittal sinus
Term
At attachment of flax cerebri and tentorium cerebelli; drains into the left transverse sinus
Definition
Straight sinus
Term
Attached margin of flax cerebelli on the occiput
Definition
Occipital sinus
Term
Formed by the junction of the straight sinus, superior sagittal sinus, and both transverse sinuses
Definition
Confluens of sinuses
Term
Venous sinuses, particularly the superior sagittal sinus, provides drainage of CSF via
Definition
Arachnoid granulations
Term
Dura mater is innervated by afferents of
Definition
Trigeminal nerve
Upper cervical spinal nerves
Term
Irritation in supratentorial compartment tends to refer pain to the
Definition
Face
Term
Irritation in the infratentorial compartment tends to refer pain to the
Definition
Back of the head and neck
Term
Supplies cranial dura mater and is a branch of the maxillary artery; travels between periosteal dura and bony skull; are the impressions left on the inner surface of the skull
Definition
Middle meningeal artery
Term
Fx. of the pterion may result in damage to which artery?
Definition
Middle meningeal artery which forms an epidural hematoma
*Recall that epidural hematoma occurs between the skull and dura mater
Term
Avascular, loosely adherent to the inner border of dura mater
Definition
Arachnoid mater
Term
Separates the external chemical environment from the CSF
Definition
barrier cell layer
Term
Fibroblasts that travel through the subarachnoid space to join with pia below to help suspend the brain within the cranium
Definition
Arachnoid trabeculae
Term
How does infectious meningitis spread?
Definition
Through subarachnoid space with CSF
Bacterial is caused by Streptococcus pneumonia or Neisseria meningitis and it's potentially fatal
Viral is caused by fungi or parasitic and it's generally self limiting
Term
How is the composition of CSF altered during infectious meningitis?
Definition
1) WBC count increases
2) Protein increases
3) Glucose concentration decreases in bacterial
Term
What are 4 signs of infectious meningitis? HLFS
Definition
Headache
Lethargy
Fever
Stiff neck
Term
Adherent to most contours of the brain and generally not observed on gross examination
Definition
Pia mater
Term
When pial cells follow blood vessels a short distance and penetrate into the parenchyma forming an envelope of perivascular space
Definition
Virchow-robin space
Term
Blood collection in the space between the dura and arachnoid mater; when "bridging veins" or superficial cerebral veins tear when entering the dural sinuses
Definition
Subdural hematoma
Term
Which bones make up the anterior cranial fossa?
Definition
Frontal, ethmoid, sphenoid
Term
Perforated cribiform plates form centrally into the cristal galli (L. Cock's comb) and provides an attachment for the
Definition
Falx cerebri
Term
What forms the posterior border of the anterior cranial fossa?
Definition
Lesser wing of the sphenoid bone and sphenoid limbus )AKA the body of the sphenoid)and Sphenoid limbus which is bounded posteriorly by prechiasmatic groove
Term
The medial end of the lesser wing of the sphenoid, the anterior clinoid process, forms an attachment point for the
Definition
Tentorium cerebelli
Term
What parts of the brain are associated with the anterior cranial fossa?
Definition
Frontal lobes
Term
What 3 bones form the middle cranial fossa?
Definition
Sphenoid, temporal, parietal
Term
What are the borders of the middle cranial fossa?
Definition
Anteriorly by the greater wings of the sphenoid
Posterior by the superior borders of the petrous temporal bones
Laterally by the squamous temporal bone
Term
The middle cranial fossa consists of the
Definition
Sella turcica in the midline and two deep concavities on each side
Term
The hypophyseal fossa of the sellsa turcica is bounded
Definition
Anteriorly by tuberculum sellae
Posterior by dorsum sellae
Term
Located behind the foramen lacerum near the apex of the petrous temporal bone
Definition
Trigeminal depression
Term
Thin osseous plate that serves the dual purpose of forming the anterior surface of the petrous temporal bone and forming the roof of the tympanic cavity and mastoid process
Definition
Tegmen tympani
Term
What lobes of the brain are in the middle cranial fossa?
Definition
Temporal lobes
Term
The diaphragm sella that attaches the A/P clinoid processes of the sella turcica in addition to the hypophyeal fossa, encapsulates
Definition
Pituitary gland
Term
What bones make up the posterior cranial fossa?
Definition
Sphenoid, occipital, and temporal
Term
What makes up the anterior border of the posterior cranial fossa?
Definition
Superior borders of petrous temporal bones and dorsum sellae
Term
What makes up the posterior border of the posterior cranial fossa?
Definition
Internal occipital protuberance and the grooves for the transverse sinuses
Term
What two structures serve as attachment sites for the falx cerebelli?
Definition
Internal occipital crest and crista gali
Term
Why is the optic nerve involved in intracranial pressure?
Definition
Since the nerve is surrounded by meninges which includes the subarachnoid space, an increase in intracranial CSF pressure results in slow venous return and interferes with axoplasmic transport resulting in papilledema or swelling of the optic disc
Term
Which nerves are susceptible to injury with increased intracranial pressure?
Definition
Oculomotor nerve because it exists midbrain and travels anterior to enter anterior edge of tentorium cerebelli
Abducent nerve because it exits brainstem in PCF and travels upward to entre the dural covering of the clivus. It travels over the superior edge of the petrous temporal bone.
Term
What two structures are resting on the clivus?
Definition
Pons and medulla
Term
What part of the brainstem is positioned between the supratentorials and infratentorial compartments?
Definition
Midbrain of the brainstem
Term
What is the relationship between volume and intracranial pressure?
Definition
An increase in volume will lead to an increase in intracranial pressure.
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