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Intro to the Brain
Everything you need to know about the brain
102
Anatomy
Undergraduate 4
11/11/2010

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Cards

Term
Cerebrum
Definition
- Largest part of the human brain - center of consciousness
Term
Cerebral Cortex
Definition
thin (1/8 of an inch), highly convoluted layer of gray matter that covers surface of cerebrum
- comprises over 40% of brain matter
Term
Cerebral nuclei (basal nuclei)
Definition
several masses of gray matter embedded deep within the underlying white matter
Term
4 main lobes of cerebral hemispheres
Definition
- frontal
- parietal
- temporal
- occipital
Term
Corpus Callosum
Definition
interconnects the two hemispheres of the cerebrum
Term
Transverse Fissure
Definition
separates the cerebrum from the cerebellum
Term
Longitudinal Fissure
Definition
divides cerebrum into two cerebral hemispheres
Term
Gyri
Definition
ridges of the cerebral cortex
Term
Sulci
Definition
grooves of the cerebral cortex
Term
Central Sulcus
Definition
separates the frontal lobe from the parietal lobe
- a.k.a."Fissure of Rolando"
Term
Lateral Sulcus
Definition
separates the temporal lobe from the frontal and parietal lobes
Term
Commissural Fibers
Definition
connect corresponding areas in the two hemispheres
Term
Association Fibers
Definition
transmit info within a single hemisphere
Term
Projection Fibers
Definition
makes connections with other parts of the brain
Term
Corpus Striatum
Definition
Caudate nucleus, putamen, and globus pallidus
- plays important role in helping to monitor and regulate muscle movements
Term
Substancia Nigra
Definition
heavily pigmented nucleus within the mid-brain
Term
Dopamine
Definition
important inhibitory neurotransmitter
Term
Damage to the basal nuclei causes:
Definition
muscular movement abnormalities, such as tremors, and disturbances in posture and muscle tone
Term
3 Fibers of the white matter
Definition
Commissural, Association, and Projection
Term
Hippocampus and amygdala
Definition
- located deep within the temperal lobe
- structurally associatied with the basal nuclei, but funtionally part of the limbic system
- involved in converting short-term memories into long-term memory
Term
Amygdala
Definition
- "almond"
- functions as the center for identification of danger
- controls the expression of strong responses to danger such as fear, rage,and aggression
Term
Domains
Definition
discrete area of the cerebral cortex where specific sensory and motor functions are localized
Term
Crossing over of the major nerve tracts causes
Definition
each hemisphere to be concerned with sensory and motor functions on the opposite side of the body
Term
Primary Motor Area
Definition
- in the pre-central gyrus
- controls the movement of specific skeletal muscles on the opposite side of the body
Term
Motor Association Area (pre-motor)
Definition
- located immediately anterior to the pre-central gyrus
- controls learned motor skills that involve repetitious patterns
- damage to this area will cause the individual to have to relearn certain skills that require repetitious and coordinated contractions
Term
Broca's Area (Speech Area)
Definition
- located in the lower part of the frontal lobe (usually in left hemisphere)
- damage to this area often results in the inability to articulate words (aphasia)
Term
Affective Language Area
Definition
a corresponding area in the hemisphere opposite Broca's area
Term
Frontal Eye Field
Definition
controls voluntary movements of the eye
Term
Where are the motor areas located?
Definition
the frontal lobe
Term
Somatosensory Area
Definition
- located in the post-central gyrus of each parietal lobe
- sensory neurons in this area enable us to be aware of the body region being stimulated (spatial discrimination)
Term
Primary Visual Area
Definition
- located at the back of each occipital lobe - damage to visual cortex usually results in functional blindness
Term
Primary Auditory Area
Definition
- located near the upper edge of each temporal lobe
Term
Olfactory Area
Definition
located on the inner surface of each temporal lobe in a small lobe-like structure called the uncus
Term
Sensory Areas
Definition
give rise to specific sensations
Term
Association Areas
Definition
special areas of the cerebral cortex that enable us to make sense of what we feel, see, hear, etc.
Term
Visual Association Area
Definition
- located in the occipital lobe
- if damaged, the individual will not be able to recognize the things they see
Term
2 Important General Association Areas
Definition
Prefrontal Cortex and Gnostic Area
Term
Prefrontal Cortex
Definition
- located in the front part of each frontal lobe
- involved with personality
Term
Gnostic Area (Wernike's Area)
Definition
- located in the parietal lobe
- important in understanding and grasping concepts
- damage will cause individual to become an imbecile
Term
Dominant Hemisphere
Definition
- dominant for language
- has greater control over mathematical abilities and logic
- for over 90% of people, the left hemisphere is the dominant hemisphere
Term
Opposite Hemisphere
Definition
- involved in intuition and artistic functions
Term
How do the dominant hemisphere and the opposite hemisphere communicate?
Definition
through connecting tracts in the corpus callosum
Term
Two main types of memory
Definition
short-term and long-term
Term
Short-term Memory
Definition
involves transient changes in the electrical potential of certain nerve cells
Term
Long-term Memory
Definition
- involves actual physical changes in the shape of certain neurons resulting in changes in neural pathways, thus forming a memory trace(memory engram)
Term
Explicit Memory
Definition
conscious recollection of previous experiences and information
Term
Implicit Memory
Definition
previous experiences aid the performance of a task without conscious awareness of the previous experience
Term
Limbic System
Definition
- "emotional brain"
- gives rise to strong emotions like fear,anger, love, pleasure, etc.
Term
Main limbic structures of the diencephalon
Definition
hypothalamus and thalamus
Term
Limbic structures in the cerebrum
Definition
olfactory cortex, hippocampus, amygdala, nucleus accumbens, and fornix
Term
Fornix
Definition
carries info from the hippocampus to the hypothalamus
Term
Nucleus Accumbens
Definition
- "reward rheostat"
- stimulated by the neurotransmitter dopamine
Term
Psychosomatic Illness
Definition
emotional illness induced by disrupting the coordination between endocrine and nervous control
Term
Cocaine
Definition
temporarily disables the system that removes dopamine from the nucleus accumbens
Term
Cingulate Cortex
Definition
- a gyrus located on the medial surface of each cerebral hemisphere just above the corpus collosum (deep in the longitudinal fissure)
- functions as a link between emotion and cognition
- controls certain emotion-related facial movements, like the smile
- abnormal and excessive activity is associated with compulsive-obsessive disorder (COD)
Term
Reticular Activating System (RAS)
Definition
- intricate system of loosely clustered neurons distributed throughout white matter tracts in the brain stem
- extends throughout the medulla oblongata, the pons, and the midbrain
Term
Two main functions of the RAS
Definition
to arouse the cerebrum and to act as a sensory filter for info entering the brain
Term
Sleep center
Definition
- located in the hypothalamus
- inhibits the activity of the RAS
Term
Neurons
Definition
incapable of mitotic division (irreplaceable)
Term
4 Ways the Brain is Protected
Definition
1) the cranial bones
2) the meninges
3) the cerebro-spinal fluid
4) the blood-brain barrier
Term
Cranial Bones
Definition
- strong, flat bones held together by interlocking joints called sutures
- curved shape of cranium makes it self-bracing
Term
Meninges
Definition
- three membranes that cover and protect the CNS - dura mater, arachnoid mater, and pia mater
Term
Meningitis
Definition
- inflammation of the meninges
- may allow bacteria or viruses to spread into the CNS
Term
Dura Septa
Definition
inward extensions or folds that anchor the brain to the cranial bones
Term
Cerebrospinal fluid (CSF)
Definition
- found in subarachnoid space, ventricles of the brain, cerebral aquaduct, and central canal of spinal cord
- cushions the brain, helps nourish the brain, and drains away metabolic wastes
Term
Choroid plexuses
Definition
frond-like masses of thin-walled blood capillaries located on the inner surface of the ventricles
Term
Total volume of CSF in average adult
Definition
- 150 ml (1/2 cup)
- replaced about every four hours
Term
Hydrocephalus
Definition
obstruction of the CSF circulation causing pressure to be exerted on the brain, leading to destruction of sensitive neurons
Term
Blood-brain barrier
Definition
- important in protecting the brain from many harmful substances
- capillaries are joined together by tight junctions, which make them much less porous and permeable
- ineffective against fats, fatty acids, and fat soluble molecules
Term
4 major advances of the nervous system
Definition
1) Nerve Nets
2) Ganglia
3) Superganglia
4) Brains
Term
Difference in brains of lower vertebrates compared to humans
Definition
In lower vertebrates, areas devoted to smell and vision are dominant. In the human, cerebral hemispheres (particularly areas associated with associative functions) form the bulk.
Term
Ganglia
Definition
small mass of neuron cell bodies from which axons can extend as nerves
Term
Superganglia
Definition
formed by the fusion of several ganglia to form "primitive brain"
Term
Neural Tube
Definition
- fluid-filled tubular structure that is the first part of the nervous system
- first step in the development of the brain
Term
3 swellings of the neural tube
Definition
prosencephalon, mesencephalon, and rhomencephalon
Term
Prosencephalon
Definition
gives rise to the cerebrum and the diencephalon
Term
Mesencephalon
Definition
gives rise to the mid-brain
Term
Rhombencephalon
Definition
gives rise to the cerebellum and most of the brain stem
Term
Fluid-filled cavity at center of neural tube
Definition
gives rise to the ventricles of the brain
Term
3 primary regions of the brain
Definition
forebrain, midbrain, and hindbrain
Term
Forebrain
Definition
consists of cerebrum and hippocampus
Term
Hindbrain
Definition
consists of the pons and cerebellum
Term
3 structural differences between the male and female brain
Definition
the corpus callosum is thicker in females, the amygdala is larger in males, and the hippocampus is larger in females
Term
MRI
Definition
Magnetic resonance imaging
Term
PET
Definition
positron-emission tomagraphy
Term
Who has more communicating fibers b/w the 2 cerebral hemispheres?
Definition
Females
Term
Stroke
Definition
"cerebro-vascular accident"
Term
Cerebral Palsy
Definition
- condition that involves impairment of the brain's control of motor functions
- usually caused by blockage of a cerebral blood vessel prior to birth
- affects 1 in every 1000 births
- causes seizures and learning disabilities
Term
Parkinson's Disease
Definition
- caused by degeneration of neurons in the substancia nigra and the basal nuclei that produce dopamine
- strikes in 50's and 60's
-
Term
Treatment for Parkinson's
Definition
- Levadopa
- transplantation of dopamine producing fetal brain tissue into patients brain
Term
Possible causes of Parkinson's
Definition
- frequent blows to the head
- exposure to certain chemicals
- inheritance
Term
Structural changes in the brain tissue of patients with Alzheimer's
Definition
- neurofibrillar tangles
- neuritic placques
Term
Symptoms associated with Alzheimer's
Definition
shortened attention span, memory loss, disorientation, confusion, and personality changes
Term
Neurotransmitter that declines in individuals with Alzheimer's
Definition
Acetylcholine
Term
Why can some drugs cross the blood-brain barrier?
Definition
they are lipid soluble
Term
Areas of the brain affected by alcohol
Definition
reticular formation, cerebellum, and cerebral cortex
Term
Chronic alcohol use causes
Definition
damage to frontal lobes, decrease in size of the brain, lower IQ, and memory impairment
Term
3 neurotransmitters affected by cocaine
Definition
dopamine, norepinephrine, and serotonin
Term
Neurological problems associated with cocaine abuse
Definition
movement problems, anxiety, depression, and hallucinations
Term
Hallucinogenic substances found in certain mushrooms
Definition
psillocybin and muscinol
Term
Psilocybin
Definition
similar to Serotonin
Term
Muscinol
Definition
similar to GABA
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