Term
__________: The body response to injury- ischemic, infectious, immunologic, neoplastic, etc (not synonymous with infection)
Eliminate the cause of the injury and initiates the repair and healing |
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Definition
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Term
Acute Inflammatory Reactions Are triggered by a variety of stimuli:
___(bacterial, viral, parasitic) & microbial toxins
___(blunt and penetrating)
___ & ___ agents (thermal injury, e.g., burns or frostbite; irradiation; some environmental chemicals)
Tissue ___(from any cause)
___ (splinters, dirt, sutures)
___ reactions (also called hypersensitivity reactions) |
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Definition
Infections
Trauma
Physical and chemical
necrosis
Foreign bodies
Immune |
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Term
| ____ inflammation is usually at the onset of injury such as an infection, necrosis, etc |
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Definition
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Term
____ inflammtion is non-healing acute inflammation
Ex. Wound that doesn’t heal initially & gets worse |
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Definition
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Term
| Chronic inflammation is triggered by a variety of stimuli: (3) |
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Definition
1.) bacteria or any microorganisms that cannot be eliminated (Tb, Fungi, etc)
2.) Foreign material or inorganic material (suture)
3.) Immune reactions |
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Term
Acute Inflammation is the Initial response to tissue injury resulting in the production of inflammatory mediators which affect blood vessels (_____) and attract inflammatory cells (______).
- Accumulation of ____
- Accumulation of ____ blood cells
Limited duration: hours, days |
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Definition
vasoactive
chemotactic
fluid
white |
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Term
Three major components of Acute Inflammation:
(1) alterations in vascular caliber that lead to an increase in blood flow (____) -> brings inflammatory cells
(2) structural changes in the microvasculature that permit ____ ____ & _____ to leave the circulation; (edema with swelling)
(3) emigration of the leukocytes from the microcirculation, their accumulation in the focus of injury, and their activation to eliminate the offending agent- major leukocytes leaving at this time are ____ = acute leukocytes |
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Definition
erythema
plasma proteins and leukocytes
neutrophils |
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Term
Acute Inflammation-Vascular Events:
Vasoactive mediators (____) at the site
of injury:
Redness (____) due to increased blood flow to the area (___)
Swelling (___) due to increased vessel wall permeability allowing of plasma protein into the perivascular space (___) |
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Definition
histamine
rubor
vasodilation
tumor
edema |
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Term
| Signs of Inflammation: (4) |
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Definition
Calor = heat
dolor = pain
rubor = redness
tumor = swelling |
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