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Intro to Cell Bio #2
Flashcards for exam #2
87
Biology
Not Applicable
09/19/2007

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Term
What are fatty acids?
Definition
Long carbon chains with a carboxyl group at the end.
Term
How do you make a triglyceride/triacylglycerol, and using what process?
Definition
By adding three fatty acids to glycerol using dehydration synthesis.
Term
What is a glycerol the backbone for?
Definition
Triglycerides and phospholipids
Term
What does saturated mean, and what is a saturated substance's main characteristic?
Definition
It has as many bonded hydrogens as possible. It makes it relatively flat.
Term
What does unsaturated mean, and what is its structure?
Definition
When in a carbon chain one carbon is double bonded to another carbon rather than single bonded to a hydrogen. It bends the molecule.
Term
What is a triglyceride's purpose?
Definition
Long term energy storage.
Term
Which are saturated, fats or oils? Why are their structures different?
Definition
Fats are saturated, oils are unsaturated. Fats are solid at room temp because saturated fats stack neatly. Oils are liquid because unsaturated fats bend, which prevents stacking.
Term
How is a phospholipid hydrophilic and hydrophobic?
Definition
It has a hydrophilic head and a hydrophobic tail.
Term
What is the composition of a phospholipid?
Definition
A phosphate group attached to a glycerol.
Term
What is a glycerol? How do you bond it to a fatty acid?
Definition
An alcohol with three carbons, each bearing a hydroxyl group. [image]
Term
What is a micelle?
Definition
A ring-shaped group of phospholipids--heads on the outside forming the ring with the tails on the inside.
Term
What is a phospholipid bilayer?
Definition
A double layer of phospholipids. The heads face outwards and the tails are protected inside.
Term
What is a sterol? Why are they grouped together?
Definition
A hydrophobic ring structure. Grouped because they're hydrophobic, though they are hydrophilic enough to dissolve things (barely).

ex. Cholesterol, testosterone.
Term
What is the purpose of a sterol?
Definition
To stabilize membranes, signal moleculres (hormones), some represent some vitamins.
Term
What are carotenoids?
Definition
Some pigment makesr in plants. Vitamin A.
Term
Who coined the term cellulae and why?
Definition
Robert Hooke because in cork tissue, it looked like it was divided into rooms.
Term
Who thought everything was made up of tiny invisible units--cells?
Definition
Theodor Schwann.
Term
Who coined the 3 tenants of modern cell theory?
Definition
Theodore Schwann and Rudolf Virchow.
Term
What is the 1st foundation/tenant of the modern cell theory?
Definition
All living organisms consist of one or more cells.
Term
What is the second foundation/tenant of the modern cell theory?
Definition
The cell is the basic unit of structure for all organisms.
Term
What is the third foundation/tenant for the moder cell theory?
Definition
All cells arise from preexisting cells.
Term
Why are cells small?
Definition
So they have a larger surface to volume ratio.
Term
What type of cell does antibacterial medicine target and why?
Definition
Prokaryotes so that they don't kill our own human cells as well.
Term
What are the parts of a prokaryote?
Definition
[image]
Term
In prokaryotes, what are pili and what do they do?
Definition
Thin, hairlike extensions of the cytoplasm/cell membrane. They can attach to tissue and also exchange genetic material.
Term
What is different about the organelles of a eukaryote compared to a prokaryote?
Definition
It has membrane-bound organelles. They compartmentalize and specialize what each has to do.
Term
What does the nucleus do?
Definition
Contains the hereditary material, encodes material, and directs the cell.
Term
What is the nucleolus and where is it?
Definition
Site for the assembly of ribosomes. In the nucleus.
Term
What is the nucleoplasm and where is it?
Definition
Inside the nucleus, it is an area that is a solution with DNA dissolved in it.
Term
What is chromatin?
Definition
DNA and proteins dissolved in the nucleoplasm.
Term
What is the nuclear envelope and where is it?
Definition
Two membranes (inner and outer) around the nucleus. Two phospholipid bilayers.
Term
What are nuclear pores and what do they do?
Definition
Holes in the nuclear envelope. Allow large molecules to get in and out of the nucleus.
Term
What is the only membrane in a cell that can disintegrate and reassemble on command?
Definition
The nuclear envelope. (Meiosis, mitosis.)
Term
What is the simplified way a protein is made?
Definition
DNA ---> RNA ---> Protein
Term
What is the central dogma of molecular biology?
Definition
DNA ---> RNA ---> Protein
Term
What are antibodies?
Definition
Proteins destined for organelles outside the cell.
Term
What are the destinations of proteins?
Definition
Organelles outside the cell. To the cytoplasm.
Term
What is the purpose of the rough endoplasmic reticulum?
Definition
Site of protein production to be secreted or transported to other cells.
Term
What makes the rough ER rough? What is the purpose?
Definition
Ribosomes stud it. They make proteins so they can be secreted into the lumen of the rough ER.
Term
What is continuous with the nuclear envelope?
Definition
Endoplasmic reticulum
Term
What are attached to the outside of the nucleus?
Definition
Ribosomes
Term
Where do proteins fold into the correct shape?
Definition
The lumen of ER
Term
What does a transport vesicle do? What is it made of?
Definition
Transport proteins from the ER to the Golgi apparatus. It's a pinched off sack from the ER.
Term
What does the Golgi do?
Definition
It's a stack of membranes that processes proteins. Things that can be added: phosphate group, sugars, etc. Once completely processed, bud off as vesicles and go to destination.
Term
What face do proteins enter the Golgi on?
Definition
The cis face
Term
What face do the proteins leave the Golgi from?
Definition
The trans face
Term
How are proteins released from the cell?
Definition
Transport vesicle fuses with plasma membrance, proteins dumped out.
Term
What does the smooth ER do?
Definition
Replaces what the rough ER loses due to vesicles.
Term
What are the specialized vesicles?
Definition
Lysosomes. Vacuoles. Transport vesicle.
Term
What do lysosomes do?
Definition
They contain digestive enzymes to help with phagocytosis.
Term
What is a vacuole's purpose?
Definition
Storage
Term
What is phagocytosis? Autophagy? (Process.)
Definition
[image]
Term
What is phagocytosis? (Define.)
Definition
Cell eating. Absorbs what needs from process, waste dumped out of cell.
Term
What is autophagy?
Definition
Lysosome breaks down a damaged organelle.
Term
What two organelles process energy?
Definition
Mitochondria and chloroplasts.
Term
What do mitochondria do?
Definition
Take certain carbon (organic) compounds, break them down, and turn them into useable energy.
Term
What are the parts of a mitochondria?
Definition
Inner membrane (has folds). Outer membrane. Matrix--inner compartment. Intermembrane space. Cristae.
Term
What are cristae?
Definition
The folds of the inner membrane.
Term
What does a chloroplast do?
Definition
photosynthesis. Energy processing rxn.
Term
What are the parts of a chloroplast?
Definition
Inner and outer membrances. Intermembrance space. Thylakoid membrance. Stroma. Inside thylakoid, thylakoid space.
Term
What is the endosymbiont theory?
Definition
Chloroplasts and mitochondria were one freeliving systems. At some point, one pre-eukaryotic cell invaded another and they started living together.
Term
Why does the endosymbiont theory make sense?
Definition
1. Lots of bacteria produce energy like mitochondria and also photosynthesis.
2. Chloroplasts and mitochondira contain their own DNA.
3. Their DNA is circular, just like bacterial DNA.
4. Ribosomes in them are similar in size to bacterial ribosomes in humans.
Term
What is the structure of a ribosome?
Definition
No membrane. Big. Made of macromolecs. Contain proteins and RNA molecs. Composed of two parts when visible: large subunit and small subunit.
Term
What do ribosomes do?
Definition
Protein synthesis.
Term
How do ribosomes know where to be?
Definition
They are told by the proteins they are producing.
Term
What is a signal sequence?
Definition
An amino acid at the beginning of the protein that tells the ribosome where to go.
Term
What is the purpose of the cytoskeleton?
Definition
Internal support.
Term
What is the cytoskeleton made up of?
Definition
Protein fibers.
Three categories of cytoskeletal fibers/elements: microfilaments, intermediate filaments, microtubules.
Term
What are microfilaments?
Definition
Actin. Act to stabilize cell structure. Tend to be involved in contraction of cells. Movement, expell things, dividing, all use contraction.
Term
What are intermediate filaments?
Definition
Stabilize cell structure, relative strong and nonelastic, forms strong connection, resists tension.
Term
What are microtubules?
Definition
Form fairly rigid skeleton. Establish cell shape. Railroad tracks for vesicles ex from ER to Golgi. Motor. Cell motility--ability of cell to move in environment. Form basis for flagella and cilia.
Term
Motor proteins
Definition
Attach to microtubules and walk down them.
Term
Flagella
Definition
Tend to be long, whiplike. Whip back and forth to propel.
Term
Cilia
Definition
Short, extension of cytoplasm. Appearance of tiny hairs. Tend to coat surface of cell. Beat in one direction--movement, recovery. Ex, trachea.
Term
What can and can't get through a membrane?
Definition
Can: Uncharged, small molecules
Can't: Charged and/or large things
Term
Integral proteins
Definition
Proteins embedded in membrane
Term
Peripheral proteins
Definition
Associated with proteins in the membrane but not embedded themselves
Term
Transmembrane protein
Definition
Passes all the way through the cell membrane
Term
What is the purpose of integral proteins?
Definition
1. Transport
2. Attachment
3. Communication
Enzymatic activity and cell-cell recognition.
Term
Receptors
Definition
How cells communicate with each other
Term
What do polysaccharides do for the cell membrane? What is their position?
Definition
Sugar ring structures, liked into chains. Communication. Point out inti extra-cellular environment.
Term
Blood types
Definition
Identifying markers on cells
Term
Lateral phospholipid movement
Definition
Movement of phospholipids along one layer
Term
Rotational phospholipid movement
Definition
Phospholipids spin around in place
Term
Flip flopping of phospholipids
Definition
Phospholipid flips from one layer to the other (rare)
Term
Flippases
Definition
Enzyme produced by smooth ER that flips phospholipids
Term
What do sterols do?
Definition
Stabilize membrane. Protect from changes in temperature.

Cholesterol in mammals.
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