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Intracranial Tumahs
Flashcard set of primary intracranial tumors, their prognoses, and common signs/symptoms.
23
Medical
Graduate
03/02/2011

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Term
Most common adult tumors
Definition
1. Metastatic brain tumors
2. Glioblastoma multiforme
3. Malignant astrocytoma
4. Meningioma
Term
Most common adolescent tumors
Definition
1. Astrocytoma
2. Medulloblastoma
3. Ependymoma
Term
Most common primary tumor:
Definition
Gliomas (50%)
Term
Originates from dura mater or arachnoid, and compresses adjacent structures, causing AMS. Common with advancing age. Usually benign; treatment is surgical.
Definition
Meningioma
Term
Malignant, rapidly-growing cystic, pulpy tumor. Common adult brain tumor that has pseudopod-like projections. Prognosis is very poor, and you can't totally remove it.
Definition
Glioblastoma multiforme
Term
Much like a glioblastoma, but course is more drawn out and benign. Surgical resection usually not possible by the time it's caught, but may be radiosensitive/chemosensitive.
Definition
Astrocytoma
Term
Seen most frequently in children, arising from the roof of the 4th ventricle. Leads to increased intracranial pressure accompanied by brainstem and cerebellar signs. Txt is surgery combined with radiation/chemotherapy.
Definition
Medulloblastoma
Term
Glioma arising from the ependyma (epithelial layer) of a ventricle (esp. 4th). Increased ICP. Best treated surgically, and radiation doesn't really work.
Definition
Ependymoma
Term
Slow-growing, and usually arises in cerebral hemisphere in adults. Calcification seen on skull radiograph. Treatment is surgical and usually successful.
Definition
Oligodendroglioma
Term
Slow-growing, and usually arises in cerebral hemisphere in adults. Calcification seen on skull radiograph. Treatment is surgical and usually successful.
Definition
Oligodendroglioma
Term
Usually presents during childhood with cranial nerve palsies and then long tract signs in the limbs. ICP occurs late. Inoperable - txt is by irradiation and a shunt.
Definition
Brainstem glioma
Term
Presents with disequilibrium, ataxia of trunk/limbs, and signs of ICP. Can be familial. Txt is surgical.
Definition
Cerebellar hemangioblastoma
Term
Usually presents during childhood with cranial nerve palsies and then long tract signs in the limbs. ICP occurs late. Inoperable - txt is by irradiation and a shunt.
Definition
Brainstem glioma
Term
Presents with increased ICP, often with impaired upward gaze (Parinaud syndrome) and other deficits suggestive of midbrain lesion. Decompression by shunting is followed by surgery. Irradiation necessary if malignant.
Definition
Pineal tumor
Term
Originates from Rathke pouch above sella turcica, depressing the optic chiasm. Also presents with endocrine dysfunction and bitemporal field defects. Usually seen in kids. Treatment is surgical.
Definition
Craniopharyngioma
Term
Ipsilateral hearing loss is most common first symptom. Later: tinnitus, hearing loss, vertigo, facial weakness/numbness. Tumor is surgically excised.
Definition
Acoustic neuroma
Term
Associated with AIDS/immunocompromised. Focal signs or disturbances of thinking/consciousness. Treatment is whole brain radiation/chemo.
Definition
Primary cerebral lymphoma
Term
Tumors in this region present with progressive intellectual decline, a slowing of mental activity, personality changes, contralateral grasp reflexes, Broca's aphasia, and anosmia.
Definition
Frontal lobe tumor
Term
Tumors in this region present with olfactory/auditory hallucination seizures, licking or smacking of the lips, a decrease in awareness or consciousness, emotional and personal changes, deja vu or jamais vu, upper quadrantopia, and sometimes Wernicke's aphasia.
Definition
Temporal lobe tumor
Term
Tumors in this area of the brain present with contralateral sensory disturbances or seizures, sensory loss (astereogenesis), lower quadrantopia, hemineglect, and thalamic syndrome (contralateral hyperpathia and spontaneous pain) if diffuse.
Definition
Parietal lobe tumor
Term
Tumors in this part of the brain present with crossed homonymous hemianopsia or crossed visual field defect, loss of color perception, other ocular problems, and cortical blindness if bilateral.
Definition
Occipital lobe tumor
Term
Tumors in this area of the brain present with CN palsies, ataxia, incoordination, nystagmus, and pyramidal and sensory deficits in the limbs, uni OR bilaterally.
Definition
Cerebellum/brainstem tumors
Term
Presentations include CN 3 and 6 palsies, as well as bilateral Babinski signs.
Definition
False localizing signs due to herniation or mass effect.
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