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Integument: Infectious Disease
VM 608 Midterm
42
Veterinary Medicine
04/14/2012

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Term
Orf
Definition
contagious viral pustular dermatitis
aka contagious echythma
zoonotic
localized to lips, oral cavity, eyelids, feet
vescile, pustules, crusts and can be proliferative
Term
Foot and Mouth Disease
Definition
picornaviridae family
does not affect horses
vesicles, erosion of mouth, mammary glands, feet
Term
Canine Distemper Virus
Definition
paramyxoviridae
respiratory, ocular, GI, neurologic, cutanous lesions
hard pad disease
nasal-digital hyperkeratosis
Term
Equine Sarcoid
Definition
caused by bovine papillomavirus 1 and 2
locally aggressive non metastatic fibroblastic skin tumor
head, legs, ventrum
Term
Superficial Pyoderma
Definition
epidermal involvment
no scarring
short duration with no lymph node involvement
pustules, crust, neutrophils
Term
Deep Pyoderma
Definition
dermis and subcutis involvment
scarring
chronic duration with lymph node involvement
may become systemic
pustule, nodule, abscess
Term
Pyotraumatic Dermatitis
Definition
aka hot spots
focal alopecia, excoriation, exudation
Term
Subcutaneous abscess
Definition
bite wound overlying area of inflammation
may not be obvious on external visual exam
Term
Causes of Subcutaneous abscess
Definition
common in male cats from fighting
Pasteurella multocida, Staphyloccocus, Streptococcus
Term
Rain Scald
Definition
dorsum and limbs affected
lichenificatioon and alopecia
branching filaments of gram positive bacteria
Term
Causes of Rain Scald
Definition
Dermtophilus congolensis
Term
Greasy Pig Disease
Definition
malodorous exudative dermatitis on pigs
Term
Causes of Greasy Pig Disease
Definition
Staphylococcus hyicus
Term
Diamond Skin Disease
Definition
diamond shaped echymosis
Term
Causes of Diamond Skin Disease
Definition
Erysipelothrix rhusiopathiae
Term
Dermatophytosis
Definition
ring worm
attacks keratinized layers and zoonotic
Term
Causes of Dermatophytosis
Definition
Microsporum spp.
Trichophyton spp.
overcrowding, high humidity, poor sanitation, poor nutrition
Term
Dermatomycosis
Definition
fungal infection of skin, hair, claws by a non-dermatophyte
Term
Causes of Dermatomycosis
Definition
Malassezia pachydermatis
Candida spp.
Term
Subcutaneous Mycoses
Definition
traumatic implantation of saprophytic fungi
organisms acquired from swimming or wading in infested water
Term
Causes of Subcutaneous Mycoses
Definition
Pythium insidiosum
Sporothrix schenckii
Term
Systemic Mycoses
Definition
primary infection by inhalation
non-specific ulcerative dermatitis usually accompanied with respiratory signs
Term
Causes of Systemic Mycoses
Definition
Blastomycosis dermatitidis
Cryptococcus neoformans
Histoplasma neoformans
Coccidiodes immitis
Term
Atopic Dermatitis
Definition
complex Type I +/- Type IV hypersensitivity to normally innocuous antigens
possible dysfunction of T-cells with overproduction of IgE
mast cells degranulation --> pruritis-->self-trauma
Term
Flea Allergy Dermatitis
Definition
combination of Type I and Type IV hypersensitivity to antigens in flea saliva
Term
Pemphigus Foliaceus
Definition
autoimmune intraepithelial blistering disease
pustule formation with coalescence
autoantigens formed against democollin-1 and desmoglien-1
Term
Sebaceous Adenitis
Definition
cell-mediated immunopathology for sebaceous gland destruction
scaling with progressive alopecia and poor coat quality
Standard poodle, Samoyed, Akita, Vizsla
Term
Hypothyroidism
Definition
atrophic dermatosis pattern
severe alopcia of the trunk extending to distal limbs
Term
Hypercortisolism
Definition
bilateral symmetrical alopecia often sparing of the head and distal extremitis
thin skin, decreased skin elasticity, delayed healing, comedones, calcinosis cutis
Term
Dysecdysis
Definition
inability to shed skin (reptile) properly
due to husbandry issues
Term
Carcinoma
Definition
meaning malignant tumor with epithelial origin
Term
Sarcoma
Definition
meaning malignant tumor with mesenchymal origin
Term
Squamous Cell Carcinoma
Definition
downgrowth of proliferating cords and nests of neoplastic cells and some have keratinizated central areas
locally invasive with low metastatic potential
Term
Sebaceous Adenoma
Definition
solitary or multiple benign tumor of sebaceous gland
can be pigments
average age is 10 years
Term
Perianal Gland Adenoma
Definition
benign hepatoid glands tumor
hormone proliferative
occur on tail, dorsum or anywhere else
castrate male and they will go away
Term
Anal Sac Carinoma
Definition
very invasive and highly metastatic
causes hypercalcemia of malignancy (PTH production)
Term
Melanocytic Neoplasia
Definition
if on eyelid or skin and <2cm most likely benign
if on oral, digits or skin and >2cm it is most likely malignant
Term
Cutaneous Soft Tissue Sarcoma
Definition
locally invasive with frequent recurrence after removal
firm to gelatinous gray to white nodular mass
Term
Lipoma
Definition
benign tumor of lipocytes
majority occur on trunk and legs
Siamese cats and all breeds of dogs
Term
Mast Cell Tumor
Definition
mean age in dogs is 8 years old
single or multiple edematous mass often hairless
ulcerated in late stages
Giemsa stain and Toludine blue stain confirms mast cells on histology
Term
Canine Cutaneous Histocytoma
Definition
common and benign tumor of Langerhans cell origin
occurs in young dogs
rapidly growing, solitary, dome-shaped nodule less than 2.5 cm in diameter
will regress on its own
Term
Cuaneous lymphoma
Definition
CD3+ and CD79a- marker
ulcerative lesions on face and ventrum