pcn and cepholasporin

- inbibit peptie bridge forming

inhibits formation of gylcan chains by preventing fomation of pTG and cell wall

- treats infections cuased by pcn rsistnant gram+

- nyst be given intravenously

interferes w transport of PTG precursos across CPMem.

topical

irreversibly 30S rib

- not affective against anerobes, entercocci, streptococci

reversibly 30S rib

-effective on some gram +/- 

- long hald life--- less freq. dose

reversibly 50S 

gram + and atypical pneumonia

50S 

last resort for life threatening

aplastic anemia

inhibits gram +/-

treats infection from intestinal perforation

clinamycin