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Introduction to biology, chemistry basics, water,macromolecues, eukaryotes and prokaryotes
148
Biology
Undergraduate 1
11/30/2011

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Term
biology
Definition
study of life, knowlege comes from conduction science observation and experimentation
Term
Inquiry
Definition
the search for information and explanation
Term
discovery science
Definition
describes natural structures and processes (based on observation and analysis of data)
Term
hypothesis testing
Definition
a hypothesis is a tentative answer to a well-framed question (leads to predictions that can be tested by observation or experimentation)
Term
data
Definition
recorded observations or items of information, often organized into tables and graphs
Term
qualitative data
Definition
descriptions rather than measurements
Term
quantitative
Definition
recorded measurements
Term
Scientific Method
Definition
obersvation
hypothesis and predictions
methodology/testing
results/analysis
conculsion/communication
Term
hierarchies
Definition
a series of ordered groupings at multiple levles within a system
Term
Emergent properties
Definition
result from the arrangement and interaction of parts within a system
Term
systems biology
Definition
constructs models for the dynamic behavior of whole biological system
Term
Negative feedback
Definition
that as more of a product accumulates, the process that creates it slows adn less of teh product is produced
Term
Positive feedback
Definition
that as more of a product accumulates, the process that creates it speeds up and more of the product is produced
Term
genes
Definition
units of inheritance that transmit information from parents to offspring
Term
Characteristics of life
Definition
order
regulation
energy processing
growth and development
reproduction
response to the environment
evolutionary adaptation
Term
Evolution
Definition
the process of change that has transformed life on Earth
Term
Darwin's points about evolution
Definition
-species showed evidence of descent with modification from common ancestors
-natural selection is the mechanism behind descent with modification
Term
structure of atoms
Definition
protons (+)
neutrons (0)
electrons (-)
Term
atomic number
Definition
use protons
Term
mass number
Definition
use protons plus neutons
Term
atomic mass
Definition
is approximated by mass number
Term
electron shell
Definition
an electron's energy level, based on state of potential energy and distance from nucleus
Term
orbital
Definition
the three dimensional space where an electron is found 90% of the time
Term
types of chemical bonds
Definition
covalent bonds (polar/nonpolar)
ionic bonds
hydrogen bonds
van der waals interactions
Term
covalent bonds
Definition
the sharing of a pair of valence elctrons by two atoms
Term
compound
Definition
two or more differnet elements combined
Term
electronegativity
Definition
an atom's attraction for electrons in a covalent bond (higher electronegativity means pulling more stongly)
Term
nonpolar covalent bond
Definition
atoms share electrons equally
Term
polar convalent bond
Definition
atoms do not shar electtons equally
Term
ionic bond
Definition
the attraction between cations and anions (electrons are NOT shared but given up and recieved)
Term
ion
Definition
a charged atom or molecule
Term
ionic compound/ salt
Definition
compounds formed by ionic bonds
Term
hydrogen bond
Definition
a noncovalent attraction between a hydrogen and an electronegative atom
Term
van der waals interaction
Definition
attractions between ever changing regions of positive and negative charge in molecules that are close together
Term
strongest type of bond
Definition
covalent
Term
weakest type of bond
Definition
hydrogen bonds van der waals interactions, and ionic bonds in water
Term
molecular shape impact
Definition
-determines how molecules interact
-molecules with similar biological effects
Term
chemical equilibrium
Definition
when the forward and reverse reaction rates are equal
Term
Four emergent properties of water contribute to Earth's fitness for life
Definition
-cohesive behavior
-ability to moderate temperature
-expansion upon freezing
-versatility as a solvent
Term
cohesion
Definition
collectively, hydrogen bonds hold water molecules together
Term
adhesion
Definition
an attraction between different substances
Term
surface tension
Definition
a measure of how hard it is to break the surface of a liquid (bug walking on water)
Term
moderation of temperature
Definition
-water absorbs heat from warmer air and releases heat to cooler air
-water can abosorb or release a large amount of heat with only a slight change in its own temperature
Term
heat
Definition
a measure of the total amount of kinetic enregy due to molecular motion in a body of matter (depends of matter's volume)
Term
temperature
Definition
a measure of the intensity of heat due to the average kinetic energy of molecules (does not depend on matter's volume)
Term
specific heat
Definition
the amount of heat that must be absorbed or lost for 1g of a substance to chang temperature by 1 degree C
Term
heat of vaporization
Definition
the heat a liquid must absorb for 1 g to be converted to gas
Term
evaporative cooling
Definition
when the remaining surface cools as a liquid evaporates
Term
water as ice
Definition
-ice floats on water (ice-hydrogen bonds are more ordered and ice is less dense)
Term
solution
Definition
a liquid homogeneous mixture of substances
Term
solvent
Definition
the dissolving agent
Term
solute
Definition
substance that is dissolved
Term
aqueous solution
Definition
one in which water is the solvent
Term
hydration shell
Definition
sphere of water molecules surrounding an ion disolved from an ionic compound in water
Term
hydrophilic substance
Definition
has an affinity for water (substances that are charged or have charged regions
Term
hydrophobic substance
Definition
does not have an affinity for water (oil molecules: have relatively nonpolar bonds)
Term
colloid
Definition
a stable suspension of fine particles in a liquid
Term
how is pH defined
Definition
-log[H+]
Term
acid
Definition
any substance that increases the H+ concentration of a solution (hydrochloric acid)
Term
base
Definition
any substance that reduces the H+ concentration of a solution (ammonia, sodium hydroxide)
Term
buffers
Definition
minimize changes in concentration of H+ and OH- in a solution
Term
acid precipitation
Definition
rain, snow, fog with pH < 5.6
Term
ocean acidification
Definition
when CO2 is realeased by fossil fuel combustion
Term
organic chemistry
Definition
the study of carbon compounds
Term
hydrocarbon
Definition
organic molecules of only C and H
-components to many organic molecules
-can undergo reactions releasinf lots of energy
-hydrophobic fuel
Term
isomers
Definition
compounds with same molecular formula, different structures (3kinds)
Term
structural isomers
Definition
have different covalent arrangements of atoms
Term
geometric isomers
Definition
have same covalent arrangements, different saptial arrangements
Term
enantiomer
Definition
mirror images of each other
Term
functional groups
Definition
the components of organic molecules that are most commonly involved in chemical reactions
Term
7 most important functional groups
Definition
-hydroxyl
-carbonyl
-carboxyl
-amino
-sulfhydryl
-phosphate
-methyl
Term
adenosine triphosphate (ATP)
Definition
primary energy transferring molecule in the cell
Term
macromolecules
Definition
large molecules, thousands of covalently connected atoms
Term
polymer
Definition
long molecule consisting of many similar building blocks
Term
monomer
Definition
small building bloock molecules
Term
dehydration reaction (condensation)
Definition
when two monomers bond together through the loss of a water molecule
Term
enzymes
Definition
macromolecules that speed up the dehydration process
Term
hydrolysis
Definition
a reaction that is the reverse of the dehydration reaction
Term
carbohydrates
Definition
sugars and the polymers of sugars
Term
monosaccharides
Definition
single sugars
Term
disaccharides
Definition
double sugars (monomers formed by glycosidic linkages)
Term
polysaccarides
Definition
polymers of sugars, up to thousands of monosaccharides (have storgage and structural roles)
Term
glycosidic linkage
Definition
a covalent bond that forms through dehydration to join two monosaccharides into a disaccharide
Term
polysaccharides for storage
Definition
starch, glycogen
Term
polysaccharides for structure
Definition
cellulose, chitin
Term
cellulose
Definition
a major component of the tough wall of plant cells
Term
chitin
Definition
another structural polysaccharide, found in arthropod exoskeleton and the cell walls of many fungi
Term
lipids
Definition
-do not form polymers
-hydrophobic parts due to nonpolar covalent bonds of hydrocarbon portions
-fats, phospholipid, steroid
Term
glycerol
Definition
a three-carbon alcohol with a hydroxyl group attached to each carbon
Term
fatty acid
Definition
a carboxyl groupd attached to a long carbon skeleton
Term
triacylglycerol
Definition
a fat molecule that has three acids joined to glycerol by ester linkage
Term
ester linkage
Definition
a bond between a hydroxyl group and a carbonxyl group
Term
saturated fatty acids
Definition
have maximum hydrogen atoms possible, no double bonds (solid at room temperature)
Term
unsaturated fatty acids
Definition
have one or more double bonds (liquid at room temperature)
Term
cardiovascular disease
Definition
-saturated fats may contribute through plaque deposits
-unsaturated fats with trans double bonds contribute even more
Term
phospholipids
Definition
two fatty acids and a phosphate group attached to glycerol (make up the cellular membrane, hydrophilic heads and hydrophobic tails)
Term
steroids
Definition
carbon skeleton consisting of four fused rings
Term
cholesterol
Definition
-a steroid
-component in animal cell membranes
-essentail in animals
Term
plasma membrane
Definition
the membrane at the boundry of a cell that selectively regulates the cell's chemical composition, made primarily of proteins and lipids
Term
seletive permeablity
Definition
allowing some substances to cross more easily than others
Term
fluid mosaic model
Definition
membrane a fluid structure with a mosaic of embedded protein
Term
polypeptide
Definition
polymers built from set of 20 amino acids, each with unique linear amino acid sequence
Term
protein
Definition
large functional molecule with a specific 3D structural arrangement of one or more polypeptide
Term
amino acids
Definition
organic molecules with carboxyl and amino groups; differ in properties due to side chains (R groups)
Term
primary structure
Definition
unique sequence of amino acids (joined by peptide bonds)
Term
secondary structure
Definition
coils and folds in a chain (a helix and B pleated sheet)
Term
tertiary structure
Definition
overaldetermined by the R group (includes hydrogen bonds, ionic bonds, van der waals interactions, and disulfide bridges)
Term
quaternary strucrure
Definition
entire protein's shape
Term
hydrophobic interactions
Definition
nonpolar side chains pushed away from water, end up in clusters at protein core
Term
denaturation
Definition
loss of native structure, unraveling (caused by pH, salt concentration, temperature)
Term
chaperonin
Definition
protein molecules that assist proper folding of other protein
Term
x-ray crystallography
Definition
mearsures diffraction of light beams through a crystal to get a 3-D image of electron density
Term
nuclear magnetic resonance spectroscopy
Definition
-does not require protein crystallization
-measures absorption of electromagnetic radiation
Term
bioinformatics
Definition
uses computer programs to predict protein structure from amino acid sequence
Term
nucleic acid
Definition
polymer called polynucleotide
Term
polynucleotide
Definition
chain of monomers called nucleotides
Term
nucleotide
Definition
consists of a nitrogenous base, a pentose sugar, phosphate group
Term
pyrimidines
Definition
(cytosine,thymine, uracil) single six membered ring
Term
purines
Definition
(adenine and guanine) six membered ring fused to five-membered ring
Term
ribosomes
Definition
structure that act as site of protein synthesis
Term
electronegativity
Definition
an atom's attraction for the electons in a covalent bond
Term
hydrocarbons
Definition
organic molecules of only C and H
-components to many organic molecules
-can undergo reactions releasing lots of energy
Term
miller-urey experiment
Definition
showed abiotic synthesis of oraganic molecules in atmosphere was possible
-resulted in some amino acids adn hydrocarbons
Term
eary earth chemical, physical processes may have produced simple cells; sequence of stages
Definition
-abiotic synthesis of small organic molecules
-joining these into macromolecules
packaging into protocells
-origins of self replication
Term
ribozymes
Definition
RNA molecules that catalyze many reactions
Term
Three Domains of Life
Definition
-bacteria
-archaea
-eukarya
Term
Basic features of all cells
Definition
-plasma membrane
-semifliud substance called cytosol
-chromosomes
-ribosomes
Term
Prokaryotic cells
Definition
-no nucleus
-no membrane bound organelles
Term
eukaryotic cells
Definition
-DNA
-membrane bound organelles
-cytoplasm
-much larger than prokaryotic cells
Term
peptidoglycan
Definition
in bacterial cell walls, network of sugar polymers cross linked by polypeptides
Term
capsule
Definition
a polysaccharide or protein layer that covers many prokaryotes
Term
fimbriae
Definition
allow to stick to substrate or other individual
Term
sex pili
Definition
longer than fibriae, allow prokaryotes to exchange DNA
Term
endospores
Definition
metabolically inactive that remain viable in harsh condition for centuries
Term
photoautotroph
Definition
energy source:light
carbon source: CO2
types of organisms: photosynthetic prokaryotes; plants, certain protists
Term
chemoautotroph
Definition
energy source: inorganic chemicals
carbon source: CO2
types or organisms: certain prokaryotes
Term
photoheterotroph
Definition
energy source: light
carbon source: organic compounds
types of organisms: certain prokaryotes
Term
chemoheterotroph
Definition
energy source: organic compounds
carbon source: organic compounds
types of organisms: manyu prokaryotes and protists
Term
obligate aerobes
Definition
require O2
Term
obligate anaerobes
Definition
are poisoned by O2
Term
facultative anaerobes
Definition
can surive with or withour O2
Term
nitrogen fixation
Definition
some prokaryotes can convert atmospheric nitrogen to ammonia
Term
methanogens
Definition
live in swamps marshes and produce methane as a waste product
Term
cyanobacteria
Definition
photoautotrophs that generate O2
Term
protons determine...
Definition
what the element is
Term
neutrons determine...
Definition
the isotope
Term
electrons determine....
Definition
the chemical behavior
Term
amphipathic
Definition
containing hydrophilic and phdrophobic regions (phospholipid)
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