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Infectious Diseases Final
Hines Prado ...
103
Veterinary Medicine
Graduate
03/16/2015

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Cards

Term
Two most common type of infectious agnets casuing resp disease ina horse
Definition
Viral
Bacterial
Term
Two big resp pathogens of horses
Definition
Herpes
Influenza
Term
Two main Herpes viruses causing resp disease in horses- and are they gamma/alpha herpes viruses?
Definition
1 4
Alpha
Term
What's in the PCR equine respiratory panel here at UT?
Definition
EHV 1 and 4
EIV
Strep equi
Term
Herpes - stabile or labile in environemnet?
Definition
Labile
Term
Why do some strains of EHV-1 cause neurologic disease?
Definition
Such high viremia that affects neuro tissues as well
Term
EHV-1 can infect 4 types of cells which are:
Definition
Epithelial
Endothelial
Neuronal
Lymphoid
Term
Where do equine herpes viruses establish latency?
Definition
CD8 lymphocytes
Neurons of trigeminal ganglia
Term
EHV incubation can be as litle as 24 hours or as long as ___days
Definition
10
Term
EHV-1 can cause these three "signs" wheres the other alphaherpesvirus in equids (EHV - ) only causes respiratory disease
Definition
Respirtory, Abortion, Neuro
EHV-4
Term
With an aborted fetus due to EHV-1 - what fetal tissues should you look for the virus?
Definition
Liver
Lung
Term
What kind of drugs might help reduce the severity of EHM?
Definition
Anti-inflammatory
Term
Does EHM affect brain. spinal cord, or either?
Definition
Either
Term
What kind of signs do mules show infected with EHM strains
Definition
Prob asymptomatic
Term
T/F You can have viral shedding w/o viremia or vice versa
Definition
True
Term
What the only known benefit of EHV-1 vaccination and EHM?
Definition
Decreases shedding
Term
This EHV might be associated with Equine pulmonary fibrosis
Definition
EHV 5
Term
Significant strain of equine influenza at this time
Definition
H3N8
Term
EHV/EIV is more lower resp tract
Definition
EIV
Term
Incuabtion period for equine influenza in days
Definition
1-5
Term
Whats a stall side test that MAY be helpful to dx equine influenza- watch out for already vaccinated horses
Definition
ELISA
Term
definitve dx for EIV
Definition
PCR
Term
T/F EIV and EHV are core vaccines
Definition
False
Term
Incubatino for equine viral arteritis in days
Definition
3-7
Term
This virus can have stallions that are persistently infected
Definition
EVA
Term
Shedding period for EVA
Definition
3-5 days AFTER viremia
Term
EVA can cause abortion storms (T/F)
Definition
True
Term
Where do you primarily see disease in equines due to adenovirus?
Definition
Immunocompromised foals like SCID
Term
Which pneumonia is more likely to cause changes in lung sounds - bacterial or viral?
Definition
Bacterial
Term
Two bacterial main pathogens to cause penumonia in young foals
Definition
Streptococcus zoo
Rhodococcus equi
Term
What does R equi look like on cytology
Definition
Gram pos coccobacillus in chinese letters
Term
Main dx tool for foal pneumonia
Definition
TTA
Term
Where does R equi come from
Definition
Soil
Term
Virulent gene of R equi
Definition
vapA
Term
the vapA gene of R equi is located where?
Definition
A plasmid
Term
Most common extrapulmonary disorder of R equi
Definition
GI
Term
List 4 extrapulmonary manifestations of R equi
Definition
GI
Synovitis
Physitis
Eye
Term
Three lab findings ( all increased values) in equine bacterial oneumonia
Definition
INC fibrinogen
INC WBC
INC platelet
Term
Tx ( at least for boards) for R equi
Definition
Rifampin + Macrolide
Term
This virulence factor of strep equi inhibits phagocytsosis
Definition
M protein
Term
Early in the course of resp disease in horses you are prob only gonna see this:
Definition
Fever
Term
Does EHV 1 or 4 cause abortion?
Definition
1
Term
_____ paresis is considered a "classic presenation" of EHM even though it can present with any type of neuro signs
Definition
Bladder
Term
The virulent strian of rhodococcus can replicate inside macrophages because it prevents the intracellular environment to ____+___
Definition
Acidify
Term
MOst common resp pathogen in horses
Definition
Streptococcus zooepidemicus
Term
Strep equi is a commensal (T/F)
Definition
False
Term
Strep zoo is a commensal (T/F)
Definition
True
Term
This rep pathogen of horses is an "AIDS defining" pathogen in humans
Definition
Rhodococcus
Term
most common site of strangles
Definition
Guttural pouch
Term
_____ abscessation is AKA bastard strangles
Definition
Metastatic abscessation
Term
Sequelae of strangles include
- this immune mediate disease
- 3 other systems affected
Definition
Purpura hemorrhagica
Myocarditis, Myopathies, Glumerulonephritis
Term
Cytology of strep equi will look like gram ____ (cocci/rods) in _____ formation
- what else will look like this?
Definition
gram +
Cocci
Chains
Strep zoo
Term
This sample gives you the most sensitive test for Strep equi however it's a pain in the ass to acquire
Definition
Guttural pouch wash
Term
Acute diarrhea in a horse is pretty much synonymous with (small/large) bowel diarrhea
Definition
Large bowel diarrhea- colitis
Term
Three main infectious causes of diarrhea in adult horses
Definition
Potomac horse fever
clostridial
salmonella
Term
Most common cause of diarrhea in horse
Definition
Colitis X
Term
How do you dx PHF
Definition
PCR on blood/feces
Term
How do you dx clostridial diarrhea
Definition
look for clostridial toxin
Term
Whats an emrging cause of diarrhea in adult horses
Definition
Coronavirus
Term
Why do colitis horses COMMONLY have neutropenia?
Definition
Endotoxin- margination neutrophils
Term
Organism causing equine monocytic ehrlichiosis
Definition
Neorickettsia risticii
Term
Lots of organisms involved in life cycle of PTF- which are likely a reservoir?
Definition
Bats and swallows
Term
Fever of unk origin you should think ,among others,
: _____ because with that disease only 66% will actually present with diarrhea
Definition
Potomac Horse Fever
Term
An easy and common way to manage for PHF
Definition
No lights near watering tanks at night
Term
This equine pathogen has been responsible for a lot of hospital closures/outbreaks and it is important to fingerprint strains
Definition
Salmonella
Term
What risk factor causes a horses to be 40x more likely to get Salmonella
Definition
Oral Abx
Term
This equine pathogen has a type 3 secretion system that plays a major role in how it causes diarrhea
Definition
Salmonella
Term
Three main infectious differentials spinal ataxia horse
Also sometimes these two rarer causes:
Definition
EPM, EHV1, WNV
Rabies, parasite migration
Term
Even tho nor 100% diagnostic- whats looked for to dx EPM in horses?
Definition
CSF antibodies to S. neurona
Term
Horses get a (low/high) viremia from WNV
Definition
Low
Term
Most horses that get WNV dont get clinical disease- however of those that show signs ___% will die
Definition
25-33
Term
Which equine encaephalitis virus can cause a viremia in horses
Definition
Venezuelan ( V for viremia)
Term
which equine enc virus is a core vax
Definition
EEV and WEV
Term
Average number days to death from onset clinical signs
Definition
5
Term
Most common presentation of EIAV
Definition
Asymptomatic
Term
90% if horses with corynebactuerium pseudo TB have
Definition
external abscesses
Term
3 syndromes assoc with pigeon fever
Definition
external abscesses
internal abscesses
swollen legs (ulcerative lymphangitis)
Term
Etiology of pigeon fever
Definition
Corynebacterium pseudotuberculosis
Term
Most cmoomon etiologic agent of piroplasmosis
Definition
Thelezia
Term
vector of piroplamosis?
Definition
Tick
Term
Tx for piroplasmosis in horses
Definition
Imidocarb diproprionate
Term
Family of hendravirus
Definition
Paramyxoviridae
Term
This equine virus can kill you
Definition
Hendrvirus
Term
Blue eared pig disease AKA
Definition
PRRS
Term
etiology of PRRS
Definition
Arterivirus
Term
This swnie disease affect all age groups
Definition
PRRS
Term
This porcine virus may be able to aerosolize over 2 miles in high density areas
Definition
PRRS
Term
How can PRRS kill fetal pigs
Definition
get in umbilical cord and cause hypoxia
Term
This porcine pathogen likes macrophages and can cause PROFOUND immunosuppression
Definition
PRRS
Term
What kind of cells does PRRS like?
Definition
Macrophages
Term
Rolling inappetance in sows ( waxing and waning of appetite)
Definition
PRRS
Term
Main problem with PRRS is that it causes
Definition
profound immunosuppression
secondary resp pathogens
Term
if wanting to prevent PRRS- how long should you quarantine new animals? ( in days)
Definition
60
Term
Depopulating is very expensive- whats another option in daeling with PRRS?
Definition
Expose everyone and hope sows give immunity to younguns
Term
Type ___ porcine circovirus is assoc with disease
Definition
Type 2
Term
Ancient pig virus
Definition
Porcine circovirus
Term
Causes lymphocyte depletion
Definition
Porcine circovirus
Term
Inclusion bodies in lyphoid tissue and ilium of pigs
Definition
Porcine circovirus
Term
Post weaning multisystemic wasting syndrome caused by:
Definition
Porcine circovirus
Term
PMWS pigs might progress to ______
Definition
PDNS ( Porcine dermatitis and nephropathy syndrome)
Term
True or False - virus isolates of PDNS are indistinguishable from those that cause PMWS
Definition
T
Term
PDNS looks identical to these foreign animal diseaes
Definition
Classical Swine Fever
African Swine Fever
Term
Ventral bight red multifocal lesions in a pig
Definition
PDNS from procine circovirus
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