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Infectious Diseases: Antibiotics General and Neuro
Master the Boards 2CK
24
Medical
Graduate
02/08/2013

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Cards

Term
What are the organisms covered by Pen G, VK (x4)

What are the extra organisms covered by Amp/Amox
Definition
Viridans, Strep pyo, oral anaerobes, Leptospira

H. Inf
E. coli
Listeria
Lyme
Salmonella
Term
What is the adverse effect of methicillin?

what is the alternitive medication to pens if pt has a rash?

anaphylaxis?
Definition
renal failure from allergic interstitial nephritis

cephs

non-betal lactam antibiotic
Term
what do first gen Cefs cover in general?

what are they?
Definition
Staphs, Streps, some gram - like e.coli

azo, alex, adrine, adrox
Term
What are the Adverse effects of Cefotetan or Cefoxitin (Fox tet)

what are they BIT for?
Definition
fox-tet gives a increased risk of bleeding and gives a disulfiram reation with alcohol

PID when combined with doxy
Term
What are the drugs Cefuroxime, loracarbef, cefprozil, cefaclor for
Definition
Pro-rac-fac and loracarbif are for resp i
Term
What is Ceftriaxone the first line treatment for?

what is the adverse effect?

what do you used instead?
Definition
Meningitis, CAP, Gonorrhea, Lyme (involving brain or heart)

Avoid in neonates due to it impaires biliary metabolism

use Cefotaxime
Term
What Ceph covers MRSA?
What Ceph covers pseudomonus?

What are Carbapenems used to treat?
Imipenem, Meropenem, Ertapenem,Doripenem?
Definition
Term
What Ceph covers MRSA?
What Ceph covers pseudomonus?

What are Carbapenems used to treat?
Imipenem, Meropenem, Ertapenem,Doripenem?
Definition
Ceftaroline (tar)
Ceftazidime

Cover Gram - bacilli
Pseudomonas exept ertapenem
Neutropenia and fever
Term
When are fluroquinolones used? (x4)
Definition
1. BIT: CAP
2. Gram neg (pseudomonads)
3. Upper UTI:Cipro for cystitis and pyelonephritis

GI:Cipro,Gimi and levo, Moxi, for GI and diverticulitis

Cipro, Gemi Levo need Metronidazole for anarobes in GI
Term
What is the adverse effect of Aminoglycosides?

What is Aztroname used for? Imipenem,Meropenem, ertapenem, doripenem?
Definition
Nephrotoxic and ototoxic


Gram - bacilli (pseudomonas)

Ertapenem does not cover pseudomonas
Term
What diseases is Doxycycline the Best treatment?

What are the adverse effects of Tetracyclines? (Doxy) x4
Definition
Chlamydia, Lyme, Rocky mountain spotted fever.

AE: tooth discoloration (children)
Fanconi Syndrome(Type II RTA proximal)
Photosynsitivity,
esophagitis and ulcer
Term
What are the adverse effects of?

TMP/SMX

Vancomycin

What causes 'gray baby syndrome'
Definition
rash, untolerated in G6PD

Redman syndrome

Chloramphenicol
Term
For Meningitis what is the BIT?

MAT?

When are these not used?
Definition
Both BIT/MAT is Lumbar puncture

CT before LP only if there is a possibility of Space occuping lesion:

Papilledema, seizures, Focal neurological, Confusion
Term
What is the Sign of Papilledema on fundoscopy?

when are latex agglutination tests done?
Definition
a blurred, fuzzy disc margin from increased intracranial pressure

when a pt has possible bacterial menengitis and has taken antibiotics before an LP, this might mess up culture?
Term
what is the Most accurate dx test for these forms of meningitis?

TB

Lyme&Rickettsia

Cryptocoocus

Viral
Definition
Acid Fast stain and culture on 3 LPs

Serologic testing, ELISIA, westernblot, PCR

Cryptococcal antigen, not India Ink

Generally dx of exclusion
Term
what LP findings have 1000s of neurtrophils?

What has elevated protein level?

what has low glucose?
Definition
Bacterial meningitis
Term
what is the best Emperical treatment for an adult with bact meningitis?

What is the MC cause of encephalitis
Definition
Ceftriacone, Vanc, and steroids

add ampicillin if Imunnocompromised to Listeria

Eldery, Immunosupp, Neonates, Prego

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HSV
Term
What are the main ass. with encephalitis? S&S

What is the BITest?

What is the MATest?
Definition
acute onset of fever and confustion.

BIT: Head CT

MAT is serology for HSV; PCR
Term
What are the main ass. with encephalitis? S&S

What is the BITest?

What is the MATest?
Definition
acute onset of fever and confustion.

BIT: Head CT

MAT is serology for HSV; PCR
Term
What are the main ass. with encephalitis? S&S

What is the BITest?

What is the MATest?
Definition
acute onset of fever and confustion.

BIT: Head CT

MAT is serology for HSV; PCR
Term
What are the main ass. with encephalitis? S&S

What is the BITest?

What is the MATest?
Definition
acute onset of fever and confustion.

BIT: Head CT

MAT is serology for HSV; PCR
Term
What are the main ass. with encephalitis? S&S

What is the BITest?

What is the MATest?
Definition
acute onset of fever and confustion.

BIT: Head CT

MAT is serology for HSV; PCR
Term
What is the treatment for Herpes Encephalitis?

If resistant?

What is the adverse effect?

What then?
Definition
Acyclovir

If resistant: Foscornet

Both have Renal toxicity
Foscornet has more

So if Acyclover develops renal toxicity decrease dose of Acyclover
Term
What are the adverse effects of Quinolones (Cipro, Gemifloxacin, levofloxacin) x2
Definition
Bone Growth abnormalities in children and pregnant women

Tendonitis and Achilles tendon rupture
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