Term
| What is the most common nosocomial infxn? |
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Definition
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Term
| Who might you suspect c.diff infxn in? |
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Definition
| 1) Abx tx w/i past 2mths 2) Diarrhea >72hrs /p admit |
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Term
| What would be an expected finding on endoscopy of a pt infected w/ c.diff? |
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Definition
| raised, yellowish-white 2-10mm plaques |
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Term
| Tx for mod-to severe diarrhea or colitis in c.diff infxn? Tx in more severe cases, pregnacy, <10yo? |
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Definition
| Metronidazole (flagyl). Vancomycin. |
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Term
| Possible complications of c.diff? |
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Definition
| Fulminant colitis: Toxic megacolon (dilated colon on KUB) or colonic perf. (free air on KUB) |
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Term
| Etiology of necrotizing fascitis? |
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Definition
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Term
| Pathology of necrotizing fascitis? |
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Definition
| Infxn destroys sub-q fat and fascia, spreads thru venous and lymphatics, cause sx of septic shock (hypotension, MOF) |
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Term
| RF of necrotizing fascitis? |
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Definition
| 1) Elderly w/ comorbid. 2)Varicella infxn |
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Term
| Dx of necrotizing fascitis? |
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Definition
| 1) GAS (s.pyogenes) on gram stain and blood culture of drainage 2) Gray necrotic fascia in surgery 3) Thrombosis of sm. art. and veins |
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Term
| Tx for necrotizing fascitis? |
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Definition
| 1) Surgery (debridement, fasciotomy, Dakan's solution) 2) Abx (IV penicillin G + IV Clindamycin) |
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Term
| Etiology of Toxic Shock Syndrome (TSS)? |
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Definition
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Term
| Disease progression of TSS? |
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Definition
| Bacteremia, deep soft tissue infxn, shock, MOF, death |
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Term
| Most common presenting sx of TSS? |
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Definition
| Fever. Also abrupt onset of severe pain. |
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Term
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Definition
| IV Penicillin G + Clindamycin. Adjunct IV immunoglobulin. Debridement prn. |
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Term
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Definition
| S aureus (toxic shock syndrome toxin producing s. aureus) |
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Term
| what are the 2 variants of TSST? |
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Definition
| 1) Menstrual-associated (tampons) 2) Non-menstrual (recent surgery, indwelling FB, diaphragm) |
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Term
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Definition
| Digital gangrene and neuropsychiatric sx |
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Term
| What is the drug of choice to tx TSST? |
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Definition
| Nafcillin or Oxacillin PLUS Clindamycin |
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Term
| How is Mycoplasma pneumoniae transmitted? When is the peak incidence in age and season? |
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Definition
| aerosol droplets. 5-20yo and Fall |
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Term
| What does U. urealyticum cause in newborns? |
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Definition
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Term
| What does M. hominis cause in women? Newborns? Immunocompromised? Post-op cardio pts? |
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Definition
| Women - cervicitis/vaginitis, endometritis and post-partum fever. Newborns - Conjunctivitis. Immuno - arthritis. Post-op - wound infxn. |
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Term
| Clinical presentation of M. pneumoniae? |
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Definition
| F/u-like sx, oropharyngitis, red TM, conjunctivitis, maculopaular or uticarial rash, minimal PE finding in lungs |
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Term
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Definition
| Macrolides (azithromycin or erythromycin) or tetracyclines (doxycycline or minocycline) |
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Term
| What are some dermatologic complications of m. pneumoniae infection? |
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Definition
| erythema multiforme (steven-johnson), uticaria, erythema nodosum, raynaud phenomenon |
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Term
| Cardiac complications of m. pneumoniae? Neurologic? Other? |
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Definition
| CHF, arrythmia. Guillain Barre, meningoencephalitis. Polyarthralgia, renal failure. |
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