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Pediatric Board Review
Infectious Disease
21
Biology
Professional
07/13/2013

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Term
Indications for the use of vancomycin
Definition
MRSA bacteremia, S. pneumo meningitis (vanc + cephalosporin), corynebacterium JK, severe B. cereus infection
Term
Treatment of tetanus
Definition
Supportive, metronidazole
Term
Tetanus prophylaxis
Definition
Clean wound and immunization within last 10 years: no treatment
Dirty wound and immunization with 5 years: no treatment
Dirty wound and immunization not UTD: TIG and immunization
Clean wound not UTD: vaccine
Term
Shigella treatment
Definition
ceftriaxone, ciprofloxacin, azithromycin
Term
RMSF
Definition
Rickettsia rickettsii, gram neg, rash, fever, headache, arthralgias, hyponatremia, thrombocytopenia
Rash on palms and soles and spreads centripetally
Diagnosed best from skin specimen
Term
Symptoms of Lyme disease
Definition
Borrelia burgdorferi transmitted by Ixodes tick, treat with doxycycline
Early localized: erythema migrans
Early disseminated:rash, flu-like illness, neuritis, aseptic meningitis, carditis
Late: arthritis
Term
Treatment for congenital toxoplasmosis
Definition
12 months of therapy with pyrimethamine, sulfadiazine, leucovorin
Term
EBV specific antibodies
Definition
IgM-VCA: acute or recent infection
EBNA: convalescent or recovered EBV
IgG-VCA: positive with any EBV infx
anti-EA: Positive with any infx except recovered or convalescent
Term
Enterovirus
Definition
Includes coxsackie, echovirus, enterovirus, polio.
Causes fever, hand foot and mouth, herpangina, meningitis, myocarditis
Term
Rabies exposure
Definition
Dog, cat or ferret: observe patient and animal, no treatment
wild animal: RIG and vaccine unless animal caught, killed and tested
Term
HIV treatment side effects
Definition
ZDV: bone marrow suppression
ddl, ddc, d4t: pancreatitiis, peripheral neuropathy
abacavir: fatal hypersensitivity
efavirenz: teratogenic
Indinavir: kidney stones
Term
Bacteriocidal agents
Definition
beta-lactams, fluoroquinolones, vancomycin, aminoglycosides, rifampin, metronidazole
Term
Treatment of meningococcal meningitis and meningococcemia
Definition
Penicillin!
Term
Summary of cephalosporins
Definition
1st gen:good for soft tissue infx, gram +
2nd gen:PID, abd infx, surgery, H. flu, neisseria, gram neg; NOT meningitis
3rd gen:good for meningitis; NOT staph
4th gen:cefepime
Term
Ehrlichia
Definition
Human monocytic and human granulocytic
white-tailed deer and white-footed mouse
Rash is less common than RMSF
anemia, leukopenia, thrombocytopenia
Peripheral blood smear, serology, PCR
Term
Ascaris lumbricoides
Definition
Intestine, live and lung
cough, dyspnea, wheezing, hemoptysis
Fever, heavy worm burden, acute intestinal obstruction and perforation
Term
Hookworm (Necator americanus)
Definition
Can penetrate the skin
Swallowed and travel to intestines
Intensely pruritic, anemia, edema growth delay
Term
Whipworm (Trichuris thrichiura)
Definition
Dysentery, colitis, rectal prolapse
Term
Enterobius (pinworms)
Definition
fecal-oral
Pruritis
Term
Trichinella spiralis
Definition
Raw or undercooked pork
striated muscle, gastroenteritis, periorbital edema, conjunctival hemorrhage, myocarditis, elevated CK
Term
Visceral larva migrans
Definition
Dog roundworm
Hypersensitivity reaction
fever, hepatosplenomegaly, malaise, peripheral eosinophilia, pneumonia, encephalitis
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