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immunology
immune system
96
Physiology
Undergraduate 4
08/04/2011

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Term
Immune System
Definition
All structures and cells involved in providing protection; modulated by cytokines and helper T cells.
Term
Immune System Functions
Definition
protect against foreign entities, stimulate an immune response (antigens), inflammation (response of tissue to injury)
Term
T Cells
Definition
lymphocyte, cellualr response. ARMY of cells, must be in contact with cells carrying antigen.produced in BONE Marrow. differentiate in thymus
Term
T Killer Cells
Definition
release cytotoxic substances into foreign cells (kills them)
Term
T Helper Cells
Definition
help activate cytotoxic cells and B cells
Term
T Memory Cells
Definition
LONG LIVED
Term
B Cells
Definition
Humoral Antibody componenet of specific immune response
Term
Active immunity
Definition
Achieved by the response of one's OWN immune system (natural or vacc.)
Term
passive immunity
Definition
temporay immunity achieved by tghe transfer of immunoglobins or T cells.. AIDS
Term
Immunity
Definition
when antibodies are available for a particular antigen. Can be obtained natuarlly (chkn pox) or via vaccination (tetanus).
Term
Vaccinations
Definition
The immune systems response to a foreign substance. The immune system produces antibodies to fight the foreign substance AND retains the memory of the substance. The substance is usually a killed or modified version. Vaccines train the animal to produce antigens prior to REAL exposure.
Term
Hormone
Definition
Chemical substances that are produced by ductless glands; released into the blood stream; carried troughout the body and produce specific regulatory effects.
Term
Endocrine Route
Definition
hormone travels via the blood to target organ
Term
Exocrine Route
Definition
hormone travels to exterior body to react with target organ-pheromones.
Term
Paracrine
Definition
Travels between the cells and is carried by interstitial fluid to the target organ.
Term
neurocrine
Definition
Hormones diffuse through synaptical clefts.
Term
epicrine
Definition
hormones pass through gap junctions (between) cells and alters functions of adjacent cells
Term
autocrine Route
Definition
produced by the cell that affects said cell
Term
Peptide Hormones
Definition
receptors in cell membrane, proteins. Binding triggers series of events in target cells.
Term
Steroid Hormones
Definition
Made up of cholesterol, 4 ring; Lipid Soluble; receptors are located in cytosol or nucleus of target cell; BINDING triggers transcription of DNA-mRNA production.
Term
Pituitary Gland
Definition
Contains hormones that affect many organs in a variety of systems. Anterior Lobe: Epithelial tissue; Poterior Lobe: Neural Tissue.
Term
Growth Hormone
Definition
Anterior Pituitary; Stimualtes changes in target organs that support growth. Stimulated by GHRH from hypothalmus.
Term
ACTH
Definition
Anterior Pituitary; Stimulates release of hormones from adrenal gland. Corticosteroids (adrenal cortex) are associated with fight or flight. Receptive by most organs; Stimulted by CRH from the hypothalmus.
Term
LH, FSH, Prolactin
Definition
regulate MALE and FEMALE repro; most repro organs have LH and FSH receptors; stimulated by GnRH from hypothalmus.
Term
AntiDiuretic Hormoce
Definition
ADH; kidney function-water retention
Term
Oxytocin
Definition
involved with smooth muscle contraction.
Term
Glucocorticoids
Definition
Adrenal Cortex; cortisol; enhance the production or glucose.
Term
Mineralocorticoids
Definition
Adrenal Cortex; regulates NA and K blood levels
Term
Catecholamines
Definition
Adrenal Medulla; variety of functions, but mostly prepare to fight or flight.
Term
thyroid Hormones
Definition
TRH from hypothalmus; TSH from anterior pituitary; T3 and T4 contain iodine & are from thyroid.
Term
Thyroid Hormones
Definition
incease BMR- increased oxygen consumptiom and heat production.
Term
Parathyroid Hormones
Definition
increase blood Ca and decrease blood P; stimulates release of Ca and P from bones; increase excretion of P in urine; formation of vitamin D in kidney.
Term
Pancreas
Definition
secretes insulin and glucagon and somatostatin (slows mobilization and production of nutrients).
Term
Insulin
Definition
decreases blood glucose by stimualting glucose uptake into tissues
Term
Glucagon
Definition
increase the blood glucose
Term
Adipose Tissue
Definition
Leptin and Adiponectin; maintain weight
Term
Eicosanoids
Definition
non-classical hormones; hormone-like-act as chemical messengers.
Term
Prostaglandins
Definition
produced in almost all tissues; used to initiate new extrous cycle; mediate inflammatory response; inhibit blood flow to stomach and kidneys.
Term
Pregastric Fermenter
Definition
ruminants & hippo & kangaroo;
Term
mouth
Definition
grinds & mixes food with saliva;
Term
hard palate in mouth
Definition
bone covered by mucous membrance
Term
soft palate in mouth
Definition
musculomucosal tissue that continues to the epiglottis base; horses=long-cannot be lifted.
Term
pharynx
Definition
common passageway for air and food; musicle directs food and liquid to esophagus and air to larynx
Term
esophagus
Definition
lining of stratified squamous epithelium; contract esophageal muscles; LEFT side of trachea.
Term
non-ruminant stomach
Definition
simple stomach (horse & pig); regions-cardia, fundus, esophageal, pyloric;
Term
cardia region in stomach
Definition
muscle forms gastroesophageal sphincter; well-developed in horse.
Term
Fundus region in stomach
Definition
bulge near cardia; stores undigested food
Term
Pyloric REgion
Definition
Pylorus; sphinter that regulates outflow to SI
Term
Ruminant Stomach
Definition
Rumen, Reticulum, Omasum (rumenoreticulum)
Term
Reticular groove
Definition
mucosa created folds that extend to abomasum
Term
Reticular groove
Definition
mucosa created folds that extend to abomasum; divides reticulum and rumen.
Term
Abomasum
Definition
TRUE glandular stomach; chemical digestion.
Term
Reticulum
Definition
crainal part; honeycomb;germentation; diaphragm is only division to heart.
Term
Rumen
Definition
takes up left side of abdominal cavity-fermentation
Term
omasum
Definition
pages of book, papillae lined; small particles pass to abomasum-larger return to reticulum. H20 absoprtion
Term
Small Intestine
Definition
D, J (supply messemtaries), I (lymph nodule). site for chemical digestion and absorption.
Term
Large Intestine
Definition
vary among species, cecum (appendix), colon.
Term
Colon
Definition
Ascending, Transverse, Descending.
Term
Absorption
Definition
Process by which molecules are transpoprted from the D.Tract, via intestinal cells and enter the vascular or lymph systems.
Term
Digestion
Definition
process by which feed particles are reduced to molecules so they can enter the body.
Term
Mechanical Action of Digestion
Definition
chewing and gut motility; large particles; increase SA for enzymatic digestion
Term
Chemical Action of Digestion
Definition
acidic breakdown of food; medium-sized particles, increase SA for enzymatic digestion.
Term
Digestive Tract functions
Definition
ingestion, mastication, digestion, absorption, elimination
Term
Peristalsis
Definition
alternating contraction/relaxing (wave)
Term
Gastric Motility
Definition
Mix ingesta with gastric juice--> mechanical digestion--> control passage of digesta into duodenum. HCl, Pepsin, Mucus.
Term
Functions of Renal System
Definition
Maintains body internal salt and water balance; maintains electrolyte, acid, and base balance; excretes metabolic waste products in the urine.
Term
Kidney Responsibilities
Definition
fluid volume and composition, fluid osmolarity and pH, body metabolites and excretion, Urea, PRODUCE Vit. D and erythropoietin.
Term
Nephron
Definition
Functional Unit; Filters blood, excretes urine; made of renal corpuscule and renal tubule.
Term
Cortical nephrons
Definition
excretory Nephron
Term
Medullary Nephron
Definition
Concentrate Urine
Term
Blood Filtration--> Urine
Definition
Fluid from proximal tubule Descends loop of Henle --> thin segment of ascending limb of Henle --> thick segment --> corticle collecting duct --> outer medullary collecting duct --> inner medullary collecting duct --> Urine.
Term
Angiotension II
Definition
maintains blood pressure in the renal system; maintains blood volume; stimualtes aldosterone.
Term
Aldosterone
Definition
Hormone in renal system; promotes secretion of K, reabsorbs Na & H20.
Term
Diabetes
Definition
High amounts of glucose in plasma and glomerular filtrate; Glucose stays in tubules and collecting ducts;
Term
Renal Failure
Definition
Gradual Loss of the Kidney's ability to filter water and fluids from the blood-Dialysis.
Term
Progesterone
Definition
Produced by CL of Ovary, placenta, and adrenal cortex; stimulates oviduct.
Term
Ovulation process
Definition
Oocyte is released and swept into uterine tubes--> Requires LH fo the follicals to cont to grow and regress through avarian cycle.
Term
EstroUs
Definition
interval between the beginning of one esTRUS and to the beginning of the next.
Term
Estrus
Definition
In Heat; Sexually receptive; NEar Ovulation time; Varies.
Term
FSH in men
Definition
promotes spermatogenesis
Term
LH in men
Definition
acts on interstital cells to promote the secretion of testosterone
Term
Testosterone
Definition
promotes developmetn and function of male accessory sex organs
Term
Epitheliochorial Placenta
Definition
chorian had direct contact with uterus (most dom. animalia)
Term
hemochorial Placenta
Definition
fetal vessels in pools of maternal blood (humans and rodents)
Term
endotheliochorial placenta
Definition
chorion has direct contact with uterus blood vessels (carnivores)
Term
Milk Production
Definition
Milk is produced by epithelial cells of alveolia of the mamary gland (modified sweat gland). Secretory droplets formed in cells-milk proteins and lactose form micelles. Then released into lumen by exocytosis.Promotes by prolaction ( enzyme activation) and oxytocin (alveoli contraction).
Term
Homeostasis
Definition
Body's maintenance of a consistant internal environment. Required by every chemical reaction in the body.
Term
Renal Blood pH Regulation
Definition
regulation of H+ concentrations. H+ is secreted into urine (acidifies) by exchanges-NAH P, HATPASE-DC, H/K collects.
Term
Respiratory Blood pH Regulation
Definition
excretes co2 which increases respiratory rate and increases expiration. pH is also excreted.
Term
Co2 levels
Definition
Respiatory Acidosis: High CO2;; Respiratory Alkadosis: Low CO2.
Term
Radiation
Definition
transfer of heat thru no contact
Term
Conduction
Definition
transfer of heat through contact
Term
Convection
Definition
transfer of heat through liquid or gas
Term
Evaporation
Definition
the loss of heat via liquid turning to vapor.
Term
Thermoneutral Zone
Definition
Your body temperatures comfort zone. Results in a change in metabolism. Varies by animals and hair coat.
Term
Responses to Cold
Definition
curl up, fur insulation, vasoconstriction, shivering, brown fat.
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