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Immunology
List of Immune Cells
27
Biology
12th Grade
03/27/2011

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Term
lysozyme
Definition
An enzyme that digests the cell walls of most bacteria; found in mucous secretions (saliva, tears, etc.)
Term
phagocyte
Definition
White blood cells that produce antimicrobial proteins, initiate inflammation, and ingest microorganisms; attach to prey via surface receptors that bind to structures like bacterial polysaccharides and then engulf the microbe, killing it with a lysosome
Term
natural killer cells
Definition
cells that attack virus-infected body cells and cancer cells; causes apoptosis
Term
lymphocyte
Definition
white blood cells that recognize antigens and produce humoral and/or cell-mediated (different) responses
Term
antibodies
Definition
defensive proteins secreted by B-lymphocytes that bind to microbes (antigens) and mark them for elimination [HUMORAL RESPONSE]
Term
cytotoxic lymphocytes
Definition
cells that directly destroy infected body cells, cancer cells or foreign tissue
Term
leukocyte
Definition
white blood cell
Term
neutrophil
Definition
60%-70% of WBC's; destroy microbes in infected tissue, self-destruct
Term
macrophage
Definition
"big eater"; develop from monocytes (5% of WBC's); spleen, lymph nodes, throughout body
Term
monocyte
Definition
5% of WBC's; circulate through blood for a few hours and then migrate into tissues and perform phagocytosis (turn into macrophages)
Term
eosinophils
Definition
discharge destructive enzymes to parasites; low phagocytic activity, but fight multicellular parasites
Term
Dendritic cells
Definition
Stimulate development of acquired immunity; can ingest microbes like macrophages
Term
complement system
Definition
30 serum proteins; inactive in the absence of infection; microbial surface substances trigger activation of the complement system and lysis of the microbes
Term
interferons a and b
Definition
Secreted by virus-infected body cells; neighboring uninfected cells produce other substances that inhibit viral reproduction (not specific)
Term
interferon y
Definition
activates macrophages
Term
defensins
Definition
secreted by activated macrophages; small proteins that damage broad groups of pathogens
Term
histamine
Definition
a chemical that triggers dilation, capillary permeability, etc.
Term
mast cells
Definition
inflammation causing cells in connective tissues
Term
chemokines
Definition
small proteins that direct the migration of phagocytes and tell them to increase production of microbe-killing compound
Term
hemocytes
Definition
invertebrate hemolymph
Term
cytokines
Definition
proteins that activate lymphocytes
Term
epitope (antigenic determinant)
Definition
the small and accessible portion of an antigen that is bound by a lymphocyte
Term
B cell receptor
Definition
Y-shaped molecule with 2 heavy chains and 2 light chains
Term
V-region
Definition
the tips of a B-cell receptor's y
Term
C-region
Definition
the end of the Y in a B-cell receptor
Term
immunoglobulins
Definition
secreted antibodies that are structurally similar to B-cell receptors, but that are not anchored in the plasma membrane
Term
T-cell receptors
Definition
alpha and beta chains with V- and C- regions
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