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Immunology
N/A
11
Biology
Graduate
01/22/2009

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Cards

Term
Oxygen Independent Killing (3)
Definition
tumor necrosis factor
Lysozyme
Hydrolytic enzymes
Term
Oxygen-dependent killing (3)
Definition
reactive oxygen intermediates
reactive nitrogen intermdiates
monochloramine NH2Cl
Term
Two types of mechanisms for digestion of foreign particles
Definition
Non-Oxygen dependent
Oxygen dependent
Term
only macrophages have
Definition
Tumor necrosis factor
Term
Things that kill foreign particles can either be (2)
Definition
Cytotoxic or Antimicrobial
Term
what two cells use oxygen independent and oxygen dependent killing?
Definition
Macrophages and Neutrophils
Term
enzyme that produces ROIs
Definition
Phagocyte oxidase
Term
when a lysosome with enzymes meets a phagosome with ingested microbes it forms a
Definition
Phagolysosome
Term
Where do lysosomal enzymes and ROIs come from?
Definition
produced withing pagolysosomes
Term
How NO different from ROi?
Definition
NO is produced in the cytosol and diffused into phagolysosomes where it is activated by the acidic PpH
Term
Name 3 ways a Neutrophil/Macrophage can get rid of microbes
Definition
1) phagolysomize kill w/ enzymes
2) phagocytose kill with ROIs and NO
3) excrete enzymes, ROIs, NO
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