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Immune response104
Immune response questions
52
Nursing
Graduate
03/07/2011

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Cards

Term

 

 

 

3 functions of the immune system

Definition

 

  1. Defense
  2. Homeostasis
  3. Surveillance
Term

 

 

This decribes a malfunction of the defense part of the immune system. This malfuntion leads to increase in infection.

Definition

 

 

 

Hyporeaction

Term

 

 

If a person has HIV and then get injured, what would you expect the inury to look like in terms of inflammation and drainage?

Definition

 

 

 

A person with HIV will have a hyporeaction and will have minimal to no inflammation and drainage, depending on the severity of the virus.

Term

 

 

If the surveillance function of the immune system is malfuntioning, what will be seen?

Definition

 

 

Malignancies and cancers. The surveillance function precieves and destroys cell mutants. If these are not found, they will turn cancerous.

Term

 

 

This malfunction in the defense area of the immune system leads to allergies

Definition

 

 

Hyperreaction

Term

 

 

The 3 physical barries that protect the body

Definition

1) Intact skin

2) Acid mantle

3) Mucous membranes

Term

 

 

What are the chemical barries that the body has, which protects it>

Definition
Acid secretions from the skin, the stomach (HCL acid), and enzymes in the tears and saliva
Term

 

 

 

How do we preserve the acid mantle of babies?

Definition
Babies are give only ONE bath in the hospital, right when they are born. After that, they may only be cleaned in the diaper area.  They are not given a full bath until the return home.
Term

 

 

Where are WBC made?

Definition

 

 

In the bone marrow.

Term

 

 

What does a high WBC count indicate?

Definition

 

 

 

Infection

Term

 

 

What does a low WBC mean?

Definition

 

 

The bone marrow is impaired, by disease of drug, and is not producing new cells (HIV)

Term

 

 

 

 

Where do T-cells mature

Definition

 

 

Thymus

Term

 

 

Where are lymphocytes and monocytes generated?

Definition

 

 

Lymph nodes and vessels

Term

 

 

What are the tree stages of defense in the immune response?

Definition

 

 

 

 

  1. Phagocytic response
  2. Humoral/Antibody response
  3. Cell mediated response
Term

 

 

During which stage of defense do we see inflammation?

Definition

 

 

1st stage: phagocytic

Term

 

 

How long does it take for inflammation to heal?

Definition

 

 

8-10 days

Term

 

 

A malfunction in which stage of defense is associated with Lupus?

Definition
The 3rd stage: Cell mediated response.  Lupus, allergues and RA occur when the cell mediated response is not turned off.  It is the T8 lymphocytes responsible for turning this off.
Term
During this stage of defense, B-lymphocites are made into antibodies
Definition

 

 

2nd stage: the humoral response

Term
Babies who are breast fed recieve this antibody from their mother
Definition
IgA. IgA is found in mothers milk (in greatest amounts in the first milk, "colostum")
Term
Which antibody passes the placenta to the fetus?
Definition
IgG. This protects the baby for the first 6 months of life, until the immune system is pretty much matured.
Term
Atrophy of the thymus glad results in this:
Definition
decreased T-cell production. Atrophy of the thymus glad is a normal part of aging and it usually occurs by age 65.
Term
Which blood test result tells us that a patient should be put on reverse precautions?
Definition
ANA <1000. This is neutropenia.
Term
Which precations should we take for a patient whose thrombocyte count is <50,000
Definition
bleeding precatuions. Use a soft toothbrush, no injections, no invasive procedures, to rectal temps, no enemas, use saftey razors.
Term
What is natural passive immunity?
Definition
When antibodies are transferred naturally from an immune mother to her baby through the placenta or the milk (IgG and IgA)
Term
During which stage of anaphylaxis does a person feel impending doom
Definition
Moderate (the second of 3 phases)
Term
Which cells are Lupus patients hypersensetive to?
Definition
B and T cells
Term
Which type of lupus affects only the skin
Definition
Discoid lupus
Term
With which autoimmune disorder might the patient present with a red rash on their face, which covers the tops of both cheeks and the bridge of the nose
Definition
The butterfly rash is indicitive of Systempic Lupus Erythematosus
Term
Hydralazine (Apresoline)
Definition
treats severe hypertension. May trigger lupus.
Term
procainamide (Pronestyl)
Definition
antiarrhythmic which may trigger lupus
Term
isoniazide (INH)
Definition
given for TB, may trigger lupus
Term
chlorpromazine (Thorazine)
Definition
antipsychotic, may trigger lupus
Term
Which ethnic groups are at greatist risk for lupus
Definition
African American and Latino
Term
What findings will show up on a CBC, for a patient with lupus
Definition

leukopenia (low WBC)

anemia (RBC, Hgb, Hct)

thrombocytopenia (low platelets)

 

Term
What is the cause of RA?
Definition
The cause is unknown. It is an autoimmune response to unknown antigens, or to an altered production and funtion of collagen
Term
What is a pannus and how does it occur?
Definition
A pannus occurs in RA when collagen is broken down. A pannus destroys cartilage and erodes the bone. It has infammatroy cells which continue to inflame and destpry the joint.
Term
What is they typcal age of the onset of RA?
Definition
35-45 years old
Term
During physcail assessment, the nurse palpates the joints of a patient with RA. How might the joint feel?
Definition
Spongy
Term
Benlysta
Definition
New drug developed specifically for Lupus. It interferes with B-lymphocyte production and is given IV Q4 weeks.
Term
How long after starting Proguanil can a patient expect to see results?  What precations should they take?
Definition

Decrease of pain may take 2-4 months. 

They need an eye exam every 6-12 months.

Term

Who recieves Gold therapy?

 

How long does it take to see results?

Definition

RA and JRA.

 

3 months.

Term
What is the peak onset of JRA?
Definition
1-3 years, 8-10 years
Term
Type of JRA that involves 4 or fewer joints
Definition
Pauciarticular Onset
Term
Type of JRA that involves 4 or more joints?
Definition
Polyarthritic onset.
Term
Type of JRA that presents with high fevers, rash, preicarditis, pruritis, neuropathy
Definition
Systemic onset
Term
In what way do the majority of JRA cases "progress?"
Definition
70% "burn out" on their own.
Term
Methotrexate
Definition
given for JRA, 2nd line when NSAIDs fail, monitor CBC, avoid pregnancy
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