Term
| How can an infectious agent cause symptoms of disease |
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Definition
-damage to organs/tissues/etc
-inflammtion, sickness inducing cytokines etc |
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Term
| Role of Vit D in treating tuberculosis |
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Definition
| Vit D binds to TLR1/2 which promotes production of cathelicidins to kill tuberculosis |
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Term
| 2 effector cell types that clear intracellular bacteria |
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Definition
| CD8 cytotoxic T cells & M1 macrophages |
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Term
| Heat shock proteins & antibacterial immunity |
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Definition
| When bacteria is phagocytized it becomes stress, releases heat-shock proteins which are DAMPS that activate the immune system |
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Term
| Immune response bias, how does it influence Johnes disease |
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Definition
| 2 forms of Johnes, PB and MB. The PB form elicits more Th1 cytokines???? I dont care |
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Term
| What effector cell types target fungi (3) |
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Definition
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Term
| Antegenic variation & cyclic parasitemia |
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Definition
| New organisms develop all the time, body will develop antibodies to fight them, then antigen starts to mutate/change, parasite population will hit a new peak, repeat |
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Term
| Immune response to helminths |
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Definition
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Term
| Intestinal helminth self-cure |
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Definition
| mounts an allergic response to the saliva of nemoatodes, creating acute inflammation that causes the worms to let go |
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