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Human Virus Family Facts
Title says it all.
25
Immunology
Undergraduate 3
12/14/2011

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Cards

Term
Template
Definition
genome structure:
morphology:
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
Term
Adeno
Definition
genome structure: dsDNA, nonsegmented
morphology: naked, icosahedral
appearance: visible penton spikes
tip: uses a protein primer
translation initiation: promoters
transmission: respiratory
vaccine: types 4 and 7 (for military)

FACTOIDS
- cells react adversely to penton spikes
- splicing was discovered in this virus
Term
Anello
Definition
genome structure: (-)ssDNA
morphology: naked, icosahedral
appearance: indistinct
tip: rolling circle replication
translation initiation: ?
transmission: parenteral, sexual
vaccine: n/a

FACTOIDS
- ~90% of adults are infected
- parenteral/sexual transmission
- no known pathology
Term
Hepadna
Definition
genome structure: partial dsDNA, nonsegmented
morphology: enveloped icosahedral
appearance: pleiomorphic (rods, circles, and dots)
tip: circular genome, ends are double-stranded; it forms an RNA transcript that extends beyond the original genome
translation initiation:
transmission: sexual, parenteral
vaccine: HBV, originally made using plasma from infected donors

FACTOIDS
- to replicate, it creates an RNA transcript, then uses reverse transcriptase
Term
Herpes
Definition
genome structure: dsDNA
morphology: enveloped, icosahedral
appearance: fried egg
tip:
translation initiation:
transmission: direct contact, respiratory
vaccine: VZV
viruses: VZV, HSV-1, HSV-2, Epstein-Barr, CMV

FACTOIDS
Term
Papilloma
Definition
genome structure: dsDNA, nonsegmented
morphology: naked, icosahedral
appearance: indistinguishable from polyoma
tip:
translation initiation:
transmission: vertical, sexual
vaccine: HPV
viruses: HPV

FACTOIDS
quasiequivalence! one type of protein can be used for both a penton and a hexon
- host must be in S phase in order to replicate
- associated with cancer
Term
Parvo
Definition
genome structure: ssDNA, nonsegmented, either strand can be packaged
morphology: naked, icosahedral
appearance: generic icosahedron
tip: ends of the genome form hairpins to act as own primer
translation initiation:
transmission:
vaccine: no
viruses: B-19

FACTOIDS
-
Term
Polyoma
Definition
genome structure: dsDNA, nonsegmented (circular)
morphology: naked, icosahedral
appearance: indistinguishable from papilloma
tip:
translation initiation:
transmission: direct contact
vaccine:
viruses:

FACTOIDS
- associated with Merkel Cell Carcinoma
Term
Pox
Definition
genome structure:
morphology:
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
Term
Arena
Definition
genome structure:
morphology:
appearance: visible ribosomes
tip:
translation initiation:
transmission:
vaccine: Junin
viruses: Junin, Machupo, LCMV

FACTOIDS
- "arena" = "sand"
Term
Borna
Definition
genome structure: (-)ssRNA, nonsegmented
morphology: enveloped, helical
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
- cap snatching, replicates in nucleus
Term
Bunya
Definition
genome structure: (-)ssRNA, 3 segments
morphology: enveloped, helical
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
Term
Calici
Definition
genome structure:
morphology:
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
Term
Filo
Definition
genome structure:
morphology:
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
Term
Orthomyxo
Definition
genome structure:
morphology:
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
Term
Paramyxo
Definition
genome structure:
morphology:
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
Term
Reo
Definition
genome structure:
morphology:
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
Term
Rhabdo
Definition
genome structure:
morphology:
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
Term
Astro
Definition
genome structure:
morphology:
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
Term
Corona
Definition
genome structure:
morphology:
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
Term
Flavi
Definition
genome structure:
morphology:
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
Term
Hepe
Definition
genome structure:
morphology:
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
Term
Picorna
Definition
genome structure:
morphology:
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
Term
Retro
Definition
genome structure:
morphology:
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
Term
Toga
Definition
genome structure:
morphology:
appearance:
tip:
translation initiation:
transmission:
vaccine:
viruses:

FACTOIDS
-
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