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Human physiology
Lecture 4
24
Biology
Undergraduate 3
01/30/2013

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Term
What are the functions of a cell membrane? How many and name
Definition
4 functions
barrier, regulator, communicator, supporter
Term
What are the two types of lipids in a cell membrane ?
Definition
phospholipids and cholestrol
Term
What is the function of cholestrol ?
Definition
make membrane impermeable to water and make membrane more tolerate of temperature low and high ( stabilzes the membrane)
Term
What forms can lipids aggragate in ?
Definition
bilayer, micelles, liposomes
Term
How many and name functions of membrane proteins?
what functions do intrinsic proteins have?
Definition
4 functions
Enzymes, Structural, receptors, transporters
Intrinsic proteins= transporters and receptors (communication)
Term
What types of channel proteins are there?
Definition
Open/leaky channels
closed/Gated channels
Term
what is the function of Gated channels and how can they be gated?
Definition
Regulate movement
Ligand gated (chemically
Electrically gated (voltage)
Mechanically gated (Temperature and stretch)
Term
Difference between channels and carrier proteins?
Definition
carrier proteins never open to both sides at one time
Term
Rate of diffusion of a membrane depends on ?
Definition
Molecules lipid solubility, surface area, thickness of membrane, resist
Term
Ficks law of Diffusion ?
Definition
SA x gradient x memb permibility /
Resistance of membrane x thickness of membrane
Term
what does diffusion resistance depend on ?
Definition
the moleculees liphilicity and the membrane composition of membrane
Term
Carrier Mediated transport has what characteristicts
Definition
specificity, saturation, competition
Term
how does secondary active transport work
Definition
couples kinetic energy of one molecule with movement of antoher
Term
what is it and how does it work Phagocytosis ?
Definition
cell eating , uses cytoskelton to engulf particles
Term
Endocytosis
Definition
cell drinking
Term
exocytosis
Definition
cell shiting
Term
What protien covers the indentations in cell membrane and vesicle surfaces in endocytosis?
Definition
clathrin
Term
What are the different types of exocytosis? describe each one
Definition
Pinocytosis- non selective
Potocytosis- non selective uses caveolae to concentrate and internalize small molecules
Selective receptor mediated- recongizes ligand and moves to clathrin coated pit where it collapses and makes vesicle which is then sent to golgi or lysoome. clathrin coat recycled
Term
Does endocytosis use the cytoskeleton ?
Definition
no
Term
Functions of exocytosis?
Definition
release of large impermeable molecules, AND replace cell membrane and membrane proteins
Term
Decribe how exocytosis works
Definition
Intra cellular secretory vesicle is transported to the membrane where it fuses
Term
Define osmotic pressue
Definition
force needed to stop osmosis
Term
Compare osmolarity vs tonicity
Definition
osmolarity depends on concentrations of particles in the solutions vs tonicity that looks at cell volumes
Term
What is transcytosis ? where are contents released
Definition
moves large molecules across MULTIPLE membranes contents released out into ECF
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