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Human Nutrition Chapter 8
Human Nutrition
153
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Undergraduate 1
02/22/2016

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Term
vitamins
Definition
essential organic (carbon-containing) substances needed in SMALL AMOUNTS in the diet for normal function, growth, and maintenance in the body
Term
does not
Definition
a compound (does/does not) qualify as a vitamin merely because the body cannot make it
Term
Vitamins A, D, E, and K
Definition
what 4 vitamins are fat-soluble?
Term
fat-soluble vitamins
Definition
dissolve in fat but not readily in water
Term
water-soluble vitamins (B vitamins and vitamin C)
Definition
dissolve in water
Term
Vitamins A, C, D, E
Definition
what 4 vitamins are needed for immunity?
Term
Vitamins C, D, K
Definition
what 3 three vitamins are needed for bone health?
Term
1. vitamin B-6
2. Vitamin B-12
3. Folate
4. Vitamin K
Definition
what 4 vitamins are needed for blood health?
Term
Vitamin A, C, E, and carotenoids
Definition
what 4 vitamins are needed for antioxidant systems?
Term
1. thiamin
2. riboflavin
3. niacin
4. pantothenic acid
5 biotin
6. vitamin B-12
Definition
what 6 vitamins are needed for energy metabolism?
Term
vitamin A
Definition
what fat-soluble vitamin's toxicity the most common?
Term
fat-soluble vitamins
Definition
carried with fat in blood in chylomicrons; not readily excreted (except vitamin K)--risk for toxicity if consumed in large amounts
Term
water-soluble vitamins (B's and C)
Definition
coenzyme form borken down and free vitamins absorbed
doesn't require carrier in blood
excreted in urine based on tissue saturation-tissue storage capacity is limited (B-6 and B-12 are exceptions as they are stored in liver)
Term
megadose
Definition
intake of a nutrient beyond estimates of needs to prevent a deficiency or what would be found in a balanced diet; 2-10X human needs
Term
increased risk for toxicity symptoms--side effects common
Definition
are there are negative consequences of consuming megadoses of vitamins?
Term
proven useful in treating several nondeficiency diseases (megadoses of a form of niacin can be used as part of blood cholesterol lowering treatment)
Definition
are there are situations in which megadoses of vitamins are useful?
Term
water soluble vitamins destroyed by improper storage or excessive cooking
-- heat, light, air, cooking in water (vitamins leach out into water), alkalinity
Definition
how can vitamins be lost/destroyed?
Term
1. riper foods contain more vitamins
2. eat foods soon after harvest (vitamins lost from time picked to consumed)
3. freeze foods that are not consumed within a few days
4. fresh is best, then frozen
Definition
how can we best preserve vitamin content of food?
Term
stored in liver and fatty tissue
Definition
where are fat-soluble vitamins stored?
Term
retinoids and carotenoids
Definition
two types of vitamin A
Term
vitamin A
(active forms-- retinol, retinal, retinoic acid)
Definition
exist only in animal products
Term
carotenoids
Definition
contained in plant pigments; phytochemicals; antioxidants
Term
precursors to Vitamin A-- can be turned into vitamin A: called provitamin A
Beta-carotene is the only cartenoid that can be sufficiently absorbed and converted to retinol
Definition
how are carotenoids related to vitamin A?
Term
1. health of epithelial cells and immune function
2. vision
3. CVD prevention-- antioxidant protection (inhibit oxidation of LDL)
4. growth, development and reproduction
5. possible cancer prevention
Definition
what are 5 functions of vitamin A and carotenoids?
Term
vitamin A and carotenoids
Definition
prevents drying of the skin and eyes (mucus production impaired with deficiency)-- maintains mucus in organs
Term
night blindness
Definition
vitamin A deficiency disorder that results in loss of ability to see under low-light conditions
Term
vitamin A
Definition
this vitamin is important for light-dark vision and color vision
Term
carotenoids
Definition
this helps prevent macular degeneration
Term
vitamin A
Definition
this vitamin is important for the differentiation and maturation of cells in early fetal growth; deficiency can cause stunted growth in children
Term
carotenoids
Definition
decrease risk of lung and oral cancers, prostrate cancer in men
Term
vitamin A deficiency
Definition
leading cause of blindness worldwide
Term
xerophthalmia
Definition
hardening of cornea and drying of the surface of the eye (lack of mucus), which can result in blindness
Term
1. liver
2. fish
3. fish oils
4. fortified milk
5. butter
6. yogurt
7. eggs
Definition
7 sources of vitamin A (animal products)
Term
1. dark green and yellow-orange vegetables
2. cooking improves bioavailability
Definition
carotenoids (plant foods) sources
Term
vegetables and protein
Definition
what two food groups contain the most vitamin A?
Term
no- hypercarotenemia: skin turns yellow-orange, particularly hands and soles of feet-- disappears when intake decreases
Definition
does carotenoids in excess amount cause toxic effects?
Term
birth defects and liver toxicity
Definition
what are two effects of excess vitamin A?
Term
vitamin D
Definition
only nutrient that is also a hormone
Term
vitamin D
Definition
this vitamin is produced in the skin upon exposure to UV light
Term
vitamin D
Definition
this vitamin regulates blood calcium
Term
vitamin D
Definition
a function of this vitamin is for gene expression and cell growth (immune system, brain and nervous system, parathyroid gland, pancreas, skin, muscles, reproductive organs)
Term
Rickets (skeletal abnormalities include bowed legs, thick wrists and ankles, curvature of spine, skull malformations, pelvic deformities)
Definition
what occurs in children with a vitamin D deficiency?
Term
osteomalacia: adult form of rickets
bones have low mineral density
Definition
what is the term for the adult form of the vitamin D deficiency?
Term
sunlight
(fatty fish (salmon) is the highest and fortified foods (milk and cereals)
Definition
the best source of vitamin D
Term
400 IU daily
Definition
what is the recommendation for infants, children, and adolescents to consume how much vitamin D?
Term
vitamin D
Definition
vegans and lactose intolerant people may have trouble meeting what vitamin needs?
Term
1. weakness
2. loss of appetite
3. diarrhea
4. vomiting
5. mental confusion
6. increased urine output
Definition
toxicity of vitamin D symptoms (excess vitamin D can lead to calcium deposits in the kidneys and other organs)
Term
vitamin E
Definition
tocopherols
Term
vitamin E donates electrons to free radicals (free radicals cause damage to cells-donating electron will neutralize it)
Definition
how does vitamin E work to prevent oxidative damage?
Term
preterm infants: vitamin E is typically transferred from mother late in pregnancy
smokers: smoking destroys vitamin E in lungs
Definition
why are preterm infants, smokers, and people with fat malabsorption particulary susceptible to oxidative damage to cell membranes?
Term
plant products and oils are best sources (oils, seeds, butter spreads)
Definition
what are groups of food that provide vitamin E?
Term
grains and proteins
Definition
what two food groups contains the most vitamin E?
Term
excess can interfere with vitamin K's role in blood clotting
can produce nausea, gastrointestinal distress, diarrhea
Definition
what is the effect of excess vitamin E?
Term
vitamin K
Definition
quinone
Term
1. plants
2. plant oils
3. fish oils
4. animal products
Definition
4 sources of vitamin K
Term
vitamin K
Definition
synthesized by bacteria in colon (unique)
Term
serves as a COFACTOR in chemical reactions, enabling proteins to bind calcium
converts soluble fibrinogen into insoluble fibrin (the clot)
Definition
what is the role of vitamin K in blood clotting?
Term
Vitamin K
Definition
this COenzyme (a vitamin) enables the activation of clotting factors
Term
vitamin K
Definition
this vitamin is routinely administered by injection shortly after birth
Term
1. green leafy vegetables
2. broccoli
3. asparagus
4. peas
5. some meats
6. eggs
7. dairy products
8. intestinal bacteria
Definition
8 sources of food of Vitamin K
Term
vitamin K
Definition
this vitamin is resistant to cooking losses; deficiencies and toxicities are rare; excesses can be excreted
Term
vegetables and fruits
Definition
what 2 food groups provide the most vitamin K?
Term
vitamin E
Definition
antioxidant; prevents breakdown of vitamin A and unsaturated fatty acids
Term
vitamin E
Definition
deficiency symptom are hemolysis of red blood cells and nerve degenration
Term
vitamin K
Definition
the deficiency symptoms are hemorrhage and fractures
Term
coenzyme
Definition
combines with inactive enyme to activate the enzyme
Term
B vitamins
Definition
this group of vitamins function as coenzymes
Term
in 1998: enrichment with folic acid to prevent neural tube defects
Definition
when did the government start requiring food to be enriched?
Term
folic acid
Definition
what was the most recent vitamin added in 1998?
Term
water-soluble vitamins
Definition
this group of vitamins has high bioavailability
Term
lipids
Definition
niacin is in food group usually?
Term
carbs
Definition
vitamin B-6 is usually in which food group?
Term
protein
Definition
vitamins B-6, B-12, C, and K, niacin, folate are all in what food group?
Term
thiamin, pantothenic acid, niacin, biotin
Definition
monosaccharides contain what 4 B vitamins?
Term
all B vitamins except B-6
Definition
fatty acids and glycerol all contain what B vitamins?
Term
B vitamins
Definition
marginal deficiencies may occur in older adults due to poor diet and alcoholism in this vitamin
Term
enrichment began in 1930s to help prevent deficiencies- initial was thiamin, riboflavin, and niacin and then in 1998 folic acid was added to enrichment
Definition
when did the government start requiring food to be enriched?
Term
thiamin
Definition
vitamin B-1
Term
thiamin (B-1)
Definition
helps release energy from carbs
important for ATP-producing energy pathways
chemical reactions that make RNA, DNA, neurotransmitters
Term
thiamin
Definition
the deficiency of this B-vitamin cause Beriberi (I can't, I can't)
Term
thiamin (B-1)
Definition
alcoholism increases the risk of this B vitamin deficiency
Term
thiamin (B-1)
Definition
symptoms of this deficiency: weakness, loss of appetite, irritability, nervous tingling, poor arm and leg coordination, pain in calves
Term
1. pork
2. whole grains
3. ready-to-eat breakfast cereals
4. enriched grains and flours
Definition
4 major sources of thiamin (B-1)
Term
riboflavin
Definition
vitamin B-2
Term
riboflavin
Definition
antioxidant role through support of GLUTATHIONE PEROXIDASE
Term
riboflavin deficiency
Definition
this B vitamin deficiency has symptoms of inflammation of the mouth and tongue, dermatitis, cheilosis
Term
grains and protein
Definition
the two food groups with the highest amount of riboflavin
Term
niacin
Definition
vitamin B-3
Term
niacin (B-3)
Definition
this vitamin has a coenzyme function in over 200 enzymatic reactions
Term
1. dementia
2. diarrhea
3. dermatitis
(3 D's)
Definition
what are the three distinct signs of niacin deficiency?
Term
niacin (B-3)
Definition
pellagra is a symptom of this B vitamin deficiency
Term
protein
Definition
best sources of niacin are from what food group?
Term
tryptophan synthesizes niacin
Definition
what is the relationship between tryptophan and niacin?
Term
niacin
Definition
megadoses of this B vitamin are recommended for treatment of cardiovascular disease
Term
niacin (B-3)
Definition
this B vitamin was the only dietary deficiency to reach epidemic proportions in US; also seen in chronic alcoholism, poverty, and malnutrition
Term
riboflavin
Definition
the dairy group is an especially rich source of what B vitamin?
Term
pyridoxine
Definition
vitamin B-6
Term
vitamin B-6 (pyridoxine)
Definition
alcoholics are susceptible to this B vitamin deficiency (decreases synthesis and absorption); symptoms include depression, vomiting, skin disorders, irritation of nerves, anemia, impaired immune response
Term
animal products and fortified ready-to-eat breakfast cereals
Definition
major source of vitamin B-6
(prydoxin)
Term
protein group
Definition
what food group provides many rich sources of B-6?
Term
unstable- heating and freezing can easily destroy it
Definition
is vitamin B-6 stable or unstable?
Term
can result in IRREVERSIBLE NERVE DAMAGE
Definition
what are the risks of vitamin B-6 supplements?
Term
pantothenic acid
Definition
vitamin B-5
Term
biotin
Definition
vitamin B-7
Term
pantothenic acid (B-5)
Definition
this B vitamin is required for synthesis of coenzyme A, allowing for release of energy from carbs, lipids, and protein
Term
grains and protein
Definition
what two food groups contain most of pantothenic acid (B-5)?
Term
biotin
Definition
intestinal bacteria synthesizes some of this B vitamin
Term
1. egg yolks
2. peanuts
3. cheese
(protein sources)
Definition
3 food sources for biotin (B-7)
Term
in raw egg white, biotin is bound to avidin, which inhibits absorption; cooking denatures avidin
Definition
why does consumption of raw egg lead to biotin deficiency?
Term
folate
Definition
vitamin B-9
Term
immature cells cannot divide in early phases of red blood cell synthesis
cannot form new DNA, results in megaloblast
Definition
why does macrocytic (megaloblastic) anemia occur during folate deficiency?
Term
neural tube defects
Definition
a defect in the formation of the neural tube occurring during early fetal development
Term
spina bifida
Definition
birth defect resulting from improper closure of the neural tube during embryonic development. the spinal cord or fluid may bulge outside the spinal column
Term
anencephaly
Definition
birth defect characterized by the absence of some or all of the brain and skull
Term
folate deficiency
Definition
this b vitamin deficiency during pregnancy may result in neural tube defects, spina bifida, and anencephaly
Term
1. green, leafy vegetables
2. fortified ready-to-eat breakfast cereals, bread, and milk
Definition
what are the richest sources of folate?
Term
400 micrograms
600 micrograms
Definition
what is the RDA for non-pregnant women and RDA or pregnant women (to accommodate increased rates of cell division and DNA synthesis in mother and fetus)
Term
folic acid
Definition
large doses of this b vitamin can mask the signs of vitamin B-12 deficiency
Term
true
Definition
vitamin B-12 (cobalamin or cyanocobalamin) are only found in foods of animal origin.
True or False?
Term
Vitamin B-12
Definition
this b vitamin requires a R-protein from salivary gland and also requires stomach acid
Term
intrinsic factor
Definition
a protein-like compound produced by the stomach that enhances vitamin B-12 absoprtion in the ileum
Term
liver
Definition
where is vitamin B-12 stored?
Term
liver
Definition
where is vitamin B-12 stored?
Term
liver
Definition
where is vitamin B-12 stored?
Term
vitamin B-12
Definition
the absoprtion of this B-vitamin requires an intrinsic factor
Term
ileum
Definition
where is Vitamin B-12 absorbed?
Term
1. mouth: salivary glands produce R-protein
2. stomach: a. HCL and pepsin release vitamin B-12 bound to protein in food
b. free vitamin B-12 binds with R-protein
c. parietal cells secrete intrinsic factor
3. small intestine: a. trypsin from pancreas release R-protein from vitamin B-12
b. vitamin B-12 links with intrinsic factor
4. ileum: vitamin B-12/intrinsic factor complex is absorbed into blood and binds to transport protein transcobalamin II
5. vitamin B-12 is stored in liver
Definition
digestion and absorption of vitamin B-12
Term
vitamin B-12
Definition
most important function of this b vitamin is for the function of folate metabolism
Term
pernicious anemia
Definition
the anemia that results from a lack of vitamin B-12 absorption; it is pernicious because of associated NERVE DEGNERATION that can result in eventual paralysis and death
Term
vitamin B-12
Definition
deficiency of this B vitamin can result in pernicious anemia and macrocytic anemia
Term
vegan diets
infants breastfed by vegetarian
Definition
what are two population groups that are at risk for vitamin B-12 deficiency?
Term
true; they suffer from an AUTOIMMUNE DISEASE that destroys the stomach cells that produce gastric acid and intrinsic factor (needed for proper absorption)
Definition
people with pernicious anemia usually do not lack vitamin B-12 in their diets. True False?
Term
1. organ meats (liver, kidneys, heart)
2. meat
3. seafood
4. ready-to-eat breakfast cereals, milk, and eggs
Definition
what are 4 food source for vitamin B-12?
Term
fortified soy or rice milk and multivitamin and mineral supplement
Definition
what sources of foods are vegans suppose to eat to get enough vitamin B-12?
Term
ascorbic acid
Definition
vitamin C
Term
strengthens structural tissues by increasing cross connections between amino acids
Definition
how does vitamin C contribute to the formation of collagen?
Term
can readily accept and donate electrons
reduce the formation of cancer-causing nitrosamines in the stomach
aids in the reactivation of vitamin E after it has donated an electron to a free radical
Definition
what are 3 ways that vitamin C functions as an antioxidant?
Term
vitamin C deficiency
Definition
scurvy occurs due to what vitamin deficiency?
Term
vegetables and fruits
Definition
what 2 food groups contains most vitamin C?
Term
1. soybeans
2. egg yolks
3. beef
4. cauliflower
5. almonds
6. peanuts
Definition
what are 6 sources of choline?
Term
thiamin, riboflavin, niacin, folic acid
Definition
grains contain what 4 B vitamins?
Term
vitamins A, K, C, and folate
Definition
vegetables contain what 4 vitamins?
Term
vitamin A and C
Definition
fruits contain which 2 vitamins?
Term
Vitamin D, riboflavin, Vitamin B-12, Choline
Definition
dairy provides what 4 vitamins?
Term
thiamin, riboflavin, niacin, biotin, vitamin B-6, Vitamin B-12, Choline
Definition
protein provides what 8 vitamins?
Term
false
Definition
True or False:
other vitamin-like compounds need to be included in the diet of the average healthy adult
Term
niacin and vitamin B-6
Definition
what two B vitamins have toxicity symptoms?
Term
choline
Definition
has toxicity symptoms of hypotension and fishy body odor
Term
a supplement contains one or more of the following ingredients: vitamin, mineral, herb or another botanical, amino acid; a dietary substance to supplement the diet, which could be an extract or a combination of the above four ingredients
Definition
what is the definition of "Supplement" as defined by the DSHEA?
Term
true
Definition
dietary supplements can be sold without proof that they are safe and effective, true or false?
Term
1. choose nationally recognized brand
2. ensure to not exceed UL from supplements and fortified foods
3. Look for U.S. pharmacopeial Convention (USP) seal
4. avoid unnecessary ingredients
Definition
what are 4 good guidelines for choosing to use a supplement?
Term
1. ingredients
2. amount per serving
3. serving size
4. suggested use
5. % DV
structure/function claims are not mandatory elements-- must include FDA warning
Definition
what are 5 components a supplement label that have to be required?
Term
an FDA warning
Definition
what is needed if there is a structure/function claim?
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