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Human Biology
Exam 2
80
Biology
Undergraduate 3
11/12/2007

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Term
disease
Definition
any abnormal functioning of a cell, tissue, organ, or organ system
Term
pathogen
Definition
organism with the genetic capacity to cause disease
Term
morbidity
Definition
incidence of disease in a population
Term
pandemic
Definition
worldwide disease
Term
endemic
Definition
rapid rise in the number of disease cases
Term
prion
Definition
infectious agent composed only of protein
Term
virus
Definition
acellular particles, no cell components, contains either DNA or RNA obligate intracellular parasites that reproduce by using host cell's machinery
Term
modes of transmission
Definition
air blood contact cuts food and water vectors
Term
communicable disease
Definition
An infectious disease that can be spread from person to person or animals to humans.
Term
gram positive bacterium
Definition
thick cell wall, contains toxins that kill WBC, lyse RBC, TSS Toxin, MRSA
Term
gram negative bacteria
Definition
thin cell wall, contains LPS (an endotoxin that leads to sepsis)
Term
streptococcus arrangement
Definition
[image]
Term
tetrad
Definition
[image]
Term
Staphylococcus aureus
Definition
toxins that kill WBC, lyse RBC, TSS toxin, MRSA
Term
E. coli O157
Definition
typically found in undercooked meats, milk, and contaminated water, leads to bloody diarrhea and possible kidney failure
Term
spirochete
Definition
[image]
Term
botulism toxin
Definition
affects the PNS, symptoms include weakness and flaccid paralysis.
Term
tetanus toxin
Definition
causes severe painful spasms and rigidity of voluntary muscles, most common symptom is lockjaw
Term
west nile virus
Definition
infection that is usually spread through the bite of an infected mosquito, and can infect an animal or human in one of three ways
Term
cipro
Definition
agent that stops bacterial nucleic acid synthesis in DNA along with anthrax and quinolones
Term
rifampin
Definition
agent that stops bacterial nucleic acid synthesis in RNA along with TB bacillus
Term
hepatitis B virus
Definition
spread through sexual contact and blood-borne transmission, it infects the liver and causes inflammation
Term
HIV
Definition
an RNA retrovirus
Term
HPV
Definition
virus that is necessary for the formation of cervical cancer
Term
acid-fast positive bacteria
Definition
consists of a thick cell wall filled with a butter like lipid. mycobacterium leprae and mycobacterium tuberculosis are common examples
Term
candida albicans
Definition
opportunistic pathogen that is found in yeast, it is immuno suppressed and treated with extended antibiotic treatment
Term
capsid
Definition
the protein shell of a virus, encloses the genetic material of the virus
Term
capsule
Definition
refers to a layer outside the cell wall of a bacteria that protect bacteria from phagocytosis
Term
prokaryotic cell
Definition
no nucleus, no organelles, all one cell
Term
EHEC
Definition
type of E. coli that is a cytotoxic toxin which attacks the kidneys
Term
ETEC
Definition
type of E. coli that is cytotonic and causes diarrhea without fever.  Commonly received from contaminated water found in underdeveloped countries
Term
Neisseria meningitidis
Definition
a gram-negative diplococcus bacteria that is a strain of meningococcus
Term
Mycobacterium tuberculosis
Definition
acid-fast positive bacteria that causes TB bacillus, also the major killer of aids
Term
latent virus
Definition
a virus that is integrated into the system but is inactive
Term
antibiotic
Definition
agent produced by living organisms that kills or inhibits other organisms (can be either bacteria or fungi) fungi = most common
Term
bacteriostatic
Definition
inhibit growth and reproduction of bacteria without killing them
Term
bactericidal
Definition
substance that kills bacteria and, preferably, nothing else
Term
antiseptic
Definition
antimicrobial substances that are applied to living tissue/skin to help reduce the possibility of infection, sepsis, or putrefaction
Term
disinfectant
Definition
antimicrobial agents that are applied to non-living materials to destroy microorganisms
Term
penicillin
Definition
antibacterial agents that stops cell wall synthesis by killing bacteria
Term
tetracycline
Definition
agent that stops bacterial protein synthesis - bacteriostatic and binds to the 70s ribosome
Term
vancomycin
Definition
"last resort drug" that is used only after antibiotic treatment has failed (MRSA)
Term
antiviral
Definition
class of medications that are used specifically to fight against viruses
Term
acylovir
Definition
antiviral agent - it fights against herpes by stopping DNA synthesis (reduces pain/spreading)
Term
amantadine
Definition
antiviral agent - fights against the flu by stopping viral uncoating (stops flu earlier)
Term
AZT
Definition
antiviral agent - fights against HIV by stopping reverse transcriptase
Term
antifungal
Definition
class of medication that is specifically used for treating fungal infections (some work against protozoa)
Term
Amphotericin B
Definition
antifungal agent - pore former; punches hole in the cell membrane
Term
Ketoconazole
Definition
antifungal agent - stops cell membrane synthesis; works against fungal infections in the system
Term
Antiprotozoal
Definition
class of medications that is used specifically for treating protozoal infections
Term
Flagyl
Definition
antiprotozoal agent - fights against trichomonas, robs the cell's ability to make ATP
Term
Pentamidine
Definition
antiprotozoal agent - fights against a severe type of pneumonia found in HIV patients
Term
Quinine
Definition
agent used to fight against smallpox, fever, and pain.  Also used to help treat cases of malaria
Term
Tamiflu
Definition
antiviral drug that is used to treat the influenza virus.  Real name is Oseltamivir
Term
Salmonella
Definition
Gram negative bacteria that invades tissue and has LPS; causes typhoid and paratyphoid fever as well as foodborne illness
Term
endotoxin
Definition
a toxin that is not secreted in soluble form by live bacteria, but is released when a bacteria is lysed
Term
sepsis
Definition
serious medical condition characterized by a whole-body inflammatory state caused by infection
Term
exotoxin
Definition
a soluble protein that is excreted by a microorganism that can cause damage to the host by destroying cells
Term
cytotonic toxin
Definition
a toxin that causes a person to lose lots of fluids
Term
cytotoxic toxin
Definition
toxins that kill cells and also cause the diptheria toxin (stops protein synthesis)
Term
toxoid
Definition
a bacterial toxin that has been weakened by chemical and is typically used in a vaccine
Term
live vaccine
Definition
a vaccine that uses a "live" bacteria or virus to elicit immunity
Term
killed vaccine
Definition
a vaccine that uses a "dead" bacteria or virus to elicit immunity
Term
Helicobacter pylori
Definition
gram negative bacterium that infects the stomach and causes stomach ulcers and possibly stomach cancers
Term
Bacillus anthracis
Definition
gram positive bacteria that is a deadly microbe which produces lethal toxins and endospores (to assure its survival through various environmental stressors). Causes anthrax.
Term
Legionella pneumophilia
Definition
gram negative bacterium that causes Legionnaire's Disease
Term
MRSA
Definition
Methicillin-resistant Staphylococcus aureus - it is resistant to both methicillin and penicillin which makes it difficult to treat
Term
Streptococcus pyogenes
Definition
gram positive bacterium that causes strep throat and toxins that kill RBC, WBC, and TSS-like toxins
Term
Vibrio cholerae
Definition
causes cholera (profuse diarrhea) which eventually causes people to simply lose all the fluids in their body
Term
DPT vaccine
Definition
a three-in-one vaccine that protects from diptheria, pertussis (whooping cough), and tetanus
Term
Gardasil
Definition
vaccine that protects against certain types of human papilloma virus
Term
flaccid paralysis
Definition
symptom of the botulinum toxin (BOTOX), causes weakness or paralysis and reduced muscle tone
Term
treponema
Definition
gram negative bacterium that causes syphilis (a spirochete)
Term
malaria
Definition
infectious disease caused by protozoan parasites with symptoms that include fever, shivering, joint pain, vomiting, anemia, and convulsions. Can relapse and reappear for years.
Term
Trichomonas
Definition
The protozoa that causes the STD Trichomoniasis
Term
Giardia
Definition
disease causing protozoa that is a flagellate found in water that colonizes and reproduces in the small intestine
Term
Histoplasma capsulatum
Definition
fungus that causes a disease in the lungs of humans, dogs, and cats
Term
opportunistic infection
Definition
infections caused by pathogens that usually do not cause disease in a person with a healthy immune system
Term
ring worm
Definition
infection of the skin characterized by a reddish to brownish raised or bumpy patch of skin that may be light in the center. Caused by a parasytic fungi
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