Shared Flashcard Set

Details

Human Behavior
Addictive Disorders I
17
Medical
Graduate
10/08/2009

Additional Medical Flashcards

 


 

Cards

Term
Where did alcohol rank in 2000 for actual causes of death?
Definition
3rd, behind tobacco and poor diet/physical inactivity
Term
What is a light drinker?
Definition
Had three or fewer drinks per week.
Term
What is a moderate drinker?
Definition
Had 4–14 drinks per week for men and 4–7 drinks per week for women.
Term
Heavy drinker
Definition
Had more than 14 drinks per week for men and more than 7 drinks per week for women.
Term
What are the drink allotments for 80 proof liquor, wine, and beer?
Definition
1.5 oz, 5 oz, and 12 oz
Term
Do genes play a role in alcohol dependence?
Definition
Yes, heritability estimates range from 50 to 60 %
Term
What is substance abuse?
Definition
A maladaptive pattern of substance use leading to clinically significant impairment or distress, as manifested by one (or more) of the following, occurring within a 12-month period: 
recurrent substance use resulting in a failure to fulfill major role obligations at work, school, or home (e.g., repeated absences or poor work performance related to substance use; substance-related absences, suspensions, or expulsions from school; neglect of children or household) 
recurrent substance use in situations in which it is physically hazardous (e.g., driving an automobile or operating a machine when impaired by substance use) 
recurrent substance-related legal problems (e.g., arrests for substance-related disorderly conduct) 
continued substance use despite having persistent or recurrent social or interpersonal problems caused or exacerbated by the effects of the substance (e.g., arguments with spouse about consequences of intoxication, physical fights)
Term
What is substance dependence?
Definition
A maladaptive pattern of substance use, leading to clinically significant impairment or distress, as manifested by three (or more) of the following, occurring at any time in the same 12-month period: tolerance, withdrawal, taken in larger amounts, persistent desire or unsuccessful efforts to cut down or control, a great deal of time is spent seeking out the substance, reduction in important social, occupational, or recreational activities, continued despite know of persistent or recurrent physical or psychological problesm
Term
what is tolerance?
Definition
a need for markedly increased amounts of the substance to achieve intoxication or desired effect 
markedly diminished effect with continued use of the same amount of the substance
Term
What is withdrawal?
Definition
The characteristic withdrawal symptoms for the substance
The same (or a closely related) substance is taken to relieve or avoid withdrawal symptoms
Term
What is GABA?
Definition
a inhibitory neurotransmitter that is stimulated by alcohol
Term
What is glutamate?
Definition
an excitatory neurotransmitter that is depressed by alcohol
Term
What are the withdrawal symptoms of alcohol?
Definition
Autonomic hyperactivity (e.g., sweating or pulse rate greater than 100 beats per minute)
Increased hand tremor
Insomnia
Nausea or vomiting
Transient visual, tactile, or auditory hallucinations or illusions
Psychomotor agitation
Anxiety
Grand mal seizures
Term
What is the differential dx for alcohol withdrawal?
Definition
thyrotoxicosis, hypoglycemia, anticholinergic drug poisoning, amphetamine or cocaine use, CNS infection or hemorrhage, withdrawal from other sedative-hypnotic agents
Term
What is CAGE?
Definition
cut down, annoyed by criticism, guilty, eye opener
Term
What are signs and symptoms of alcohol abuse?
Definition
Reduced diligence at work or home
Moodiness or irritability
Acne rosacea
Unexplained bruises
Accidents
Evidence of liver damage
Elevated GGT (gamma-glutamyl transferace) or MCV (mean corpuscular volume
Term
What is the effect of alcohol on thiamine?
Definition
blocks its absorption and can lead to Wernicke's Encephalopathy-Korsakoff's syndrome: vision change, gait change, confabulation
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