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1st rxn of beta oxidation
What enzyme causes dehydrogenation (double bond) |
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2nd rxn of beta oxidation
What enzyme causes hydration? (Adds H20, basically an H on one Carbon and an OH on another) |
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3rd rxn of beta oxidation of fatty acids
What causes an oxidation rxn? (removing an H from one carbon bound oxygen so now it is a double bond) |
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| What causes a cleavage thiolysis? (removal of a CH2-CO) 4th rxn of beta oxidation of fatty acids |
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Definition
| Thiolase (also known as beta-ketoacyl CoA thiolase |
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| In the oxidation of palmitate there are 7 FADH2, how much ATP is this?? |
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| In the oxidation of palmitate there are 7 NADH made, how much ATP is this? |
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| In the oxidation of palmitate there are 8 Acetyl CoA's made, how much ATP is this? |
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| Palmitate oxidation requires an ATP activation of how many ATP? |
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| The net total ATP made in the oxidation of palmitate is |
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| What enzyme in fatty acid synthesis negatively affects CAT 1? |
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| What enzyme in fatty acid synthesis negatively affects thiolase? |
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| What enzyme in fatty acid synthesis negatively affects beta hydroxy CoA DH? |
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| High energy charge results in a decrease in Isocitrate DH, what three things increase as a result? |
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Definition
| Citrate, Acetyl CoA CO2lase, FA synthesis |
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| With an increase in citrate, there is also an increase in acetyl CoA and Malonyl CoA but what two things decrease? |
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| Glucagon results in a decrease in acetyl CoA CO2lase, and an increase in what two things? |
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| Hypoketotic hypoglycemia and dicarboxylic aciduria are both symptoms of MCAD deficinecy. Besides decreased GNG, fasting, and increased glucose use, what is another result of hypoketotic hypoglycemia? |
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| Hypoketotic hypoglycemia and dicarboxylic aciduria are both biochemical symptoms of MCAD deficiency. What is a result of dicarboxylic aciduria? |
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| During starvation/low CHO, there is increased FA degrad, resulting in more Acetyl CoA which results in ? ? ? due to it being an energy source for non-hepatic tissue (skeletal cardiac) and brain |
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| Diabetic ketoacidosis also results in increased ? ? and a ? pH |
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| To go from beta gamma unsaturated fat and convert that to alpha beta unsaturated fatty acid you need ? ? ? |
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| For the oxidation of a cis unsaturated fatty acid you need two enzymes which are, in order.... |
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Definition
| Enoyl CoA Hydratase followed by beta hydroxy FA CoA racemase |
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