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HT
HT
12
Pharmacology
Professional
11/02/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
Captopril
Definition
*ACE inhibitor
-mild to moderate HT
-no orth static hypo
-not to be used when pregers!
USE ACE INHIBITOR FOR
*in heart failure
**in diabetics- dec development of glomerulopathies
-less effective in African american
Term
Enalapril
Definition
*ACE inhibitor
*prodrug (liver metabolized)
Term
Fosinopril
Definition
*ACE inhibitor
*prodrug (liver metabolized)
Term
Losartan
Definition
*Angiotensin Receptor Blockers (ARBs)
-similar to ACE inhibitors with SE etc but no cough
SE: dizziness, fetal toxicity, hyperkalemia
Term
Valsartan
Definition
*Angiotensin Receptor Blockers (ARBs)
-similar to ACE inhibitors with SE etc but no cough
SE: dizziness, fetal toxicity, hyperkalemia
Term
Aliskiren
Definition
*Renin inhibitor
-MOA: binds renin, inhibits the cleavage of angiotensinogen to produce AI
-dec BP similar w/ARB
**DONT use during preg!!
Term
Nifedipine
Definition
*Arteriolar calcium channel blocker
-blocks L-type calcium channels, dec vascular resistance
*often first one tried
Term
Verapamil
Definition
*Arterial and cardiac Ca2+ channel blocker
-useful against arrhythmias
Term
Diltiazem
Definition
*Arterial and cardiac Ca2+ channel blocker
-useful against arrhythmias
Term
Hydralazine
Definition
*smooth muscle vasodilator
-MOA: inc NO, inc K+ permeability
Term
Minoxidil
Definition
*Smooth muscle vasodilator
-MOA: inc K channel opening
SE: w/hirsutism
Term
Sodium Nitroprusside
Definition
-used for HT crisist- moment to moment control
-very toxic
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