Term
| conjugated equine estrogen (HRT) |
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Definition
ORAL HRT - positive effect on lipid profile
INCREASE NUMBER CLOTS |
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Term
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Definition
ORAL HRT MICRONIZED TO ELIMINATE FIRST PASS
positive effect lipids, INCREASE # CLOTS |
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Term
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Definition
Long time standard of therapy (prevents endometrial cancer)
OPPOSES EFFECT E ON LIPIDS
typically combined transermal patch |
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Term
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Definition
MICRONIZED ORAL
NO OPPOSE EFFECT E LIPID
typicall combined with transdermal patch |
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Term
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Definition
No period one year (45-55 avg 51)
huge rise FSH
only adrenal Estrone left over |
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Term
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Definition
1. hot flashes (increase NE hypot)
2. loss sleep (decreased serotonin)
3. osteoporsis (prevents not restore)
4. urogenital atrophy
5. mood swings
6. loss memory
men treated androgens prostate cancer can have hot flashes as well |
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Term
| peri-menopausal vs menopausal TX |
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Definition
peri: low does ethynal estradiol oral COC or IUD (high rate unintended preg)
menopausal: limited duration soon after |
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Term
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Definition
lower risk clots
smaller improvment on lipid profiles compared to oral |
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Term
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Definition
Rings: advantages and disadvantages locally
usually used if vaginal atrphy primary problem (doesnt go away like hot flashes) |
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Term
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Definition
1. E 1-24 P10-25 3-6 days free
2. continuous combined |
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Term
| womens health initiative 2002 |
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Definition
27000 women on oral CEE/MPA
avg age = 63 |
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Term
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Definition
| HRT initated in older women with active heart disease has negitive effects |
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Term
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Definition
Observational ongoing 1970's
Longterm HRT cardioprotective but offset by increase breast cancer |
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Term
| current thoughts cardio protection |
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Definition
timing = everything therefore need initiate @ menopause
P may hurt heart
E only decreases breast cancer <10
increases >10
only use 2-5 years |
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Term
| Risk estrogen and progesterin |
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Definition
Blood clots
dementia
increase breast cancer |
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Term
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Definition
gallbladder disease, dementia, blood clots
no increase breast cancer |
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Term
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Definition
| NOT OK HEART DISEASE BREAST CANCER |
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