Term
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Definition
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Term
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Definition
| Ankylosing spondylitis, Psoriasis, IBD, Reiter's syndrome (uveitis, urethritis, ankylosing spondylitis (sacro-ileal enthesitis)) |
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Term
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Definition
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Term
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Definition
| MS, SLE, Goodpasture's, hay fever |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| Pernicious anemia (B12 def), Hashimoto's thyroiditis |
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Term
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Definition
| Steroid-responsive nephrotic syndrome |
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Term
| HLA (what is it, what does it do?) |
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Definition
| Human Leukocyte Antigen genes, encode MHC which present antigen fragments to Tcells and bind TCR |
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Term
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Definition
HLA-A, HLA-B, HLA-C
(Almost) all nucleated cells
Presents mostly intracellular peptides
Antigen loaded in RER
Viral immunity
Pairs with beta2-microglobulin
which aids in txpt to cell surface |
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Term
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Definition
HLA-DR, HLA-DP, HAL-DQ
Only on APCs
Antigen loaded after release of invariant chain in acidifed endosome |
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