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| PIs causing bad diarrhea? |
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| duranavir, lopinavir, nelfinavir |
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| ddI is a bad combo with ... |
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| TDF is a bad combo with ... |
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| this drug needs testing for HLA-B5701? |
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| specifically monitor amylase, and uric acid with what? |
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| incr peripheral neuropathy, pancreatitis, incr lactic acidosis |
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| no drug interactions or extra monitoring with? |
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| emtricitabine & lamivudine |
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| not for males with CD4 >400 or females >250, or ppl with mod/severe liver problems |
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| what drug still works with K103N? |
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| zidovudine, lamivudine, & abacavir |
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| tenofovir & emtricitabine |
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| tenofovir, emtricitabine, & efavirenz |
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| which PI is ALWAYS boosted w/ ritonavir? |
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| which drug needs Trofile testing to be CCR5 tropic only? |
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OI's corrolated with CD4 ...
>500 |
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• Bacterial infections,
• HIV meningitis,
• tuberculosis,
• vaginal candidiasis |
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OI's corrolated with CD4 ...
<500 |
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• Herpes zoster,
• herpes simplex,
• oral thrush |
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OI's corrolated with CD4 ...
<300 |
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• Kaposi’s sarcoma,
• non-Hodgkins lymphoma |
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OI's corrolated with CD4 ...
<200 |
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• HIV-associated dementia,
• PCP |
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OI's corrolated with CD4 ...
<150 |
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OI's corrolated with CD4 ...
<100 |
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• Aspergillosis,
• cryptococcosis,
• esophageal candidiasis,
• histoplasmosis,
• PML toxoplasmosis |
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OI's corrolated with CD4 ...
<50 |
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• Cytomegalovirus (CMV),
• mycobacterium avium (MAC) |
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| CD4 count < 200 or hx thrush |
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| indications for toxo prohy? |
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Indications:
1. Positive toxoplasma IgG serology (plus)
2. CD4 count nadir <100 cells/mm3 |
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• Primary prophylaxis is generally not used
• Secondary prophylaxis in retinitis or GI disease
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