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HIV/AIDS
Ch. 21 Immune Deficiencies
18
Nursing
Undergraduate 1
11/24/2011

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Term
Primary (congenital) Immune Deficiency
Definition
In which one or more parts of the immune system are not functioning properly from birth. Usually the result of genetic mutations.
Term
Secondary Immune Deficiency
Definition
Acquired after birth as a result of viral infection, toxin introduction, or medical therapy that can interfere with the immune system. Most common AIDS.
Term
Retrovirus
Definition
Similar to human cells that have genetic material.
Term
Normal T Cell Count
Definition
800-1000 cells/mm3
Term
Initial Manifestation of HIV
Definition
Fever, night sweats, chill, HA and muscle aches. Rash and sore throat is also common.
Term
Opportunistic Infection
Definition
Infections cause by organisms that are present as part of the normal environment but are kept in check by normal immune function. Occur due to profound immune suppression.
Term
Clinical Category A
Definition
-HIV Positive
-Manifestations may or may not be present (flu-like s/s)
-Persistently enlarged lymph nodes (lymphadenopathy)
-500-800 CD4+
Term
Clinical Category B
Definition
-Patient with HIV infection and also has one or more opportunistic diseases or infection on the side.
-200-499 CD4+
Term
Clinical Category C
Definition
-HiV positive who has AID (<200) and more than one other health problem related to decrease immune function.
-<200
Term
HIV Progression
Definition
From HIV to AIDS it can take months or years, depending on how the HIV was acquired. With transfusion it is quicker. Sexual encounter are more slower. It also depends on the frequency or re-exposure, stress, nutrition and other STDs.
Term
Viremia
Definition
a High HIV concentration in the blood or viral load.
Term
Window Period
Definition
The period between infection and antibody production by the immune system. ELISA test, which can be a false negative or False positive.
Term
NARTIs
Definition
Suppress viral replication
Term
NNRTIs
Definition
Suppress viral replication along with NARTIs
Term
Protease Inhibitors
Definition
Prevent viral replication and release of viral particles.
Term
Fusion Inhibitors
Definition
Prevent the HIV infection in the body from spreading.
Term
Entry Inhibitors
Definition
Prevent the spread of HIV infection inside the boy along with fusion inhibitors.
Term
Integrase Inhibitors
Definition
Prevent viral protein synthesis and viral replication.
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