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Histology
Epithelium
60
Veterinary Medicine
Professional
09/01/2008

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Term
Epithelium
Definition
The cellular covering of internal and external surfaces of the body. Consists of cells joined by small amounts of cementing substances.
Term
Simple Squamous Epithelium
Definition
Epithelium composed of a single layer of plate- or scalelike cells best suited for the transportation of substances across the cytoplasm
Term
Mesothelium
Definition
The layer of flat cells derived from the mesoderm, that line the body cavity of the embryo. In Adults, it forms the simple squamous epithelium that covers the surface of all true serous membranes (peritoneum, pericardium, and pleura)
Term
Endothelium
Definition
The layer of epithelium cells that lines the cavities of the heart and the blood and lymph vessels. Sometimes applied to other internal epithelial surfaces.
Term
simple cuboidal epithelium
Definition
Epithelium composed of a single layer of cells that are generally cube shaped. Usually associated with secretion and/or absorption
Term
simple columnar epithelium
Definition
Single layered epithelium in which the height of individual cells easily exceed their width. Usually associated with secretion and absorption. Often possess a variety of cell modifications (microvilli, cilia, glycocalyx, etc.)
Term
microvilli
Definition
: Slender, cylindrical, cytoplasmic processes from the free surface of a cell. They function to increase surface area for absorption
Term
pseudostratified
Definition
Being an epithelium consisting of closely packed cells which appear to be arranged in layers but all of which are attached to the basement membrane
Term
Stratified squamous epithelium
Definition
The most common of the multilayered epithelia, covering most of the external body parts which functions to protect underlying tissue from dessication.
Term
Keratinized (cornified):
Definition
Being converted into keratin (fibrous proteins forming horny epidermal tissue)
Term
Stratified cuboidal/columnar epithelium
Definition
Bilayered epithelium where one layer always touches the basement membrane, while the other always doesn’t
Term
Transitional Epithelium
Definition
Multilayered epithelium found only in the urogenital system capable of changing its shape between stratified squamous and stratified cuboidal epithelium
Term
Basement Membrane
Definition
The delicate extracellular supporting layer of mucopolysaccharides and protein underlying all epithelia.
Term
Basal Lamina
Definition
The cell layer of the basement membrane which lies next to the cell membrane of the basal epithelial cell and is made solely by the overlying epithelial cell
Term
reticular lamina
Definition
Cell layer of the basement membrane that consists of small irregular bundles of small collagen fibrils with a layer of ground substance. Made by both epithelium and surrounding tissue
Term
hemidesmosomes
Definition
Structures which provide points of adhesion to anchor cytoskeletal elements to basal cell membranes. Often randomly placed along the lateral sides of the epithelial cell
Term
Cell Junctions
Definition
Structure within tissue of a multicellular organism. Abundant epithelial cells, and consist of protein complexes, which function to provide contact between neighboring cells, or the cell and extracellular matrix
Term
Zona Occludens
Definition
tight junction” a cell junction that forms a morphological barrier between the intercellular spaces of adjacent cells. Part of the junctional complex of columnar epithelium
Term
Adhering Junctions
Definition
“Zonula Adherens” Cell junction that functions to bind adjacent epithelial cells. Occurs as a band or zone that encompasses the entire apical perimeter of the cell in columnar or cuboidal epithelia.
Term
Desmosomes
Definition
spot welds” that provide one of the structural units that bind epithelial cells together. Half units are called hemidesmosomes
Term
Junctional Complex
Definition
An attachment point between epithelial cells, typically composed to three components, the Zonula Occludens (Tight junctions), the Zonula Adherens , and Macula Adherens (Desmosomes).
Term
Gap Junction
Definition
“Nexus” - Specialized platelike junctions that mediate the flow of current from one cell to another. Located on the deeper lateral surfaces of apposing cells. Typically hundreds if not thousands connect one cell to another
Term
Cell Surface Specializations
Definition
Modifications or specializations of the free or luminal surfaces of epithelial cells found among the different forms of epithelia
Term
Brush Border
Definition
Specialization of the free surface of a cell, consisting of minute cylindrical processes (microvilli) that increase surface area
Term
Glycocalyx
Definition
Glycoprotein surface coat that covers the entire cell and is prominent in intestinal cells with microvilli.
Term
Stereocilia
Definition
Very long microvilli that line the luminal surface of certain columnar cells. Non-motile and possessing actin cores
Term
cilia
Definition
cell processes possessing an internal microtubular substructure designed for contractility. Move substances such as mucous by means of metachronal rhythm
Term
Glandz
Definition
An aggregation of cells specialized to secrete or excrete materials not related to their ordinary metabolic needs
Term
Glands
Definition
An aggregation of cells specialized to secrete or excrete materials not related to their ordinary metabolic needs
Term
Endocrine glands
Definition
ductless glands that discharge their secretions(hormones) directly into the blood
Term
Exocrine Glands
Definition
which discharge through ducts into luminal or free space
Term
Unicellular Goblet Cell
Definition
Solitary mucus secreting cell primarily of the intestinal and respiratory epithelium.
Term
Multicellular
Definition
Glands which occur as sheets of epithelial cells with secretory functions
Term
simple glands
Definition
Cluster of secretory cells (adenomeres) that connect to the surface by unbranched ducts
Term
Straight tube
Definition
straight configuration of simple glands with a tubular endpiece (adenomere
Term
Coiled
Definition
coiled configuration of simple glands
Term
Cuplike (acinus and alveolus)
Definition
rounded configuration of adenomere
Term
Compound Glands
Definition
Glands in which adenomeres empty into more than one duct. Can all be same type or mixed (tubular, or tubuloalveolar
Term
Branched Tubular
Definition
tubular configuration of gland with branched adenomere configuration
Term
Branched alveolar
Definition
Alveolar (acinar) configuration of gland with branched adenomere configuration
Term
tubuloalveolar
Definition
mixed configuartion of compound gland including both tubular and alveolar adenomeres
Term
secretory units
Definition
the basic unit of secretion in the gland
Term
acinus
Definition
round configuration of the adenomere
Term
alveolus
Definition
round configuration of the adenomere ( same as acinus
Term
adenomeres
Definition
the blind terminal portion of the gland which is the functional portion of the organ the endpiece
Term
duct
Definition
a passage with well defined walls for the passage of excretions or secretions
Term
lobe
Definition
a more or less well defined portion of an organ or gland
Term
lobules
Definition
a small segment of lobe, especially one of the smaller divisions making up the lobe
Term
myoepithelial cell
Definition
Specialized epithelial cells that have contractile capability which are tightly woven as a single intermittent layer around the periphery of each adenomere, but inside the basement membrane.
Term
epitheliod tissue
Definition
Cell aggregates of epithelial origin with common structures and secretory functions
Term
Mode of secretion
Definition
Manner in which exocrine glands secrete their products
Term
merocrine secretion
Definition
Secretion method by which glandular products are secreted by exocytosis. Cell product is delivered through the cell membrane by membrane-bound vesicles that are fused with the cell membrane and in this manner keeps the cell membrane intact
Term
exocytosis
Definition
the discharge from a cell of the particles that are too large to diffuse through the plasma membrane
Term
Apocrine secretion
Definition
Secretion method by with part of the apical cytoplasm is discharged along with the secretory product.
Term
Holocrine secretion
Definition
Secretion method involving cell detachment and subsequent death. The entire content of the cell contributes to the secretory product
Term
Compostion of Secretions
Definition
Chemical makeup of secretions from the glands
Term
Serous Glands
Definition
Glands wich produce clear, watery proteinaceous fluid
Term
Mucous Glands
Definition
Glands which produce viscid fluid of glycoproteins and polysaccharides
Term
mucous glands
Definition
Glands which produce viscid fluid of glycoproteins and polysaccharides
Term
Mixed glands
Definition
Glands that produce both serous and mucous secretions
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