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HHD Mycobacter TB Polasky
TB
72
Medical
Professional
03/12/2009

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Cards

Term
3 types of mycobacter organisms
Definition
mycobacter tb
mycobacter leprosae
mycobacter avium intracellulare complex
Term
what percent of the world's population is infected yearly with tuberculosis
Definition
one percent yearly
Term
how many deaths annually from tb?
Definition
2 million
Term
what percent of the world's population is currently infected with tb?
Definition
33
Term
TB is a____ aerobe
Definition
obligate thus it is in the lung
Term
Tb is fast or slow growing?
Definition
slow-difficult to culture
Term
Tb is____ staining
Definition
acid fast...high lipid content of the cell wall. lightly gram positive
Term
primary tb
Definition
usually confined to lung, asymptomatic, detected by PPD test. Ghon complex is a calcified granuloma in the middle or lower lung along with perihilar nodes which are calcified.
Term
secondary or reactivated tuberculosis
Definition
m tuberculosis is notkilled by the host immune but rather walled off in granulomas.
Reactivation can happen
Term
In what percent of people does tuberculosis never reactivate?
Definition
90 percent of people with a primary infection and no other risk factors never reactivate.
Term
Diabetics have a ___ percent of secondary reactivation
Definition
30 percent lifetime
Term
HIV/ silicosis patients have a ___ percent chance for reactivation
Definition
7-10 percent per year.
Term
Symptoms of secondary tuberculosis
Definition
fever, weight loss, productive cough with yellow white sputum and hemoptysis. reactivation can occur in lung kidney cns bone elsewhere.
Term
miliary tb
Definition
millet seeds tubercles disseminated over body.
Term
tb and hiv
Definition
tb is common secondary infection to hivboth due to new and reinfections.
-faster
-worse
-no cavitation
Term
diagnosis of tb
Definition
ppd-48-72 hours later
immuno compromised people may not respond to tb due to anergic t cells.
Term
ppd size categories
Definition
5mm-+chest, immunosuppressed, close contact
10mm akk others
15 mm-low risk person 4 or older
Term
Xray positive findings
Definition
granuloma
ghon's complex
Term
Is culture a good idea with tb
Definition
would work but not well as it is a slow growing organis,
Term
sputum smear used to detect TB?
Definition
yes because it is fast and cheap, but it is not as sensitive as culture.
Term
What stain should i use to diagnose tb?
Definition
AFB or fluorochrome
Term
cxr normal
Definition
latent tb infection
Term
cxr abnormal
Definition
tb disease
Term
sputum and cultures negative
Definition
latent tb
Term
sputum and or cultures positve
Definition
tb disease
Term
asymptomaticv
Definition
tb infection
Term
symptoms usually present
Definition
tb disease
Term
non infectious
Definition
latent
Term
infectious
Definition
tb disease
Term
is a person with a positive ppd a tb case?
Definition
no not if in latent state
Term
first line tb drugs
Definition
Rifampin Isoniazid Pyrazinamide Ethambutol
isoniazid
pyrazinamide
rifampin
ethambutol
Term
SHould you identify and treat skin test positive people
Definition
yes to stop progression.
Term
BCG vaccine
Definition
debatable efficacty, causes skin test positivity.
Term
DOTS
Definition
political commitment
microscopy
uninterrupted supply of drugs
surveillance and monitoring
directly observed treatment for 6-8 months.
Term
mycobacterium other than tb
Definition
not transmissible
only culture diagnosed
difficult to treat
not a public health con cern
no tracking systems
Term
mycobacteria order?
Definition
actinomycetales
Term
tuberculosis is in the top ___ infectious killers in the world
Definition
3
Term
right upper lobe infiltrate pneumonia with cavity?
Definition
cavitatous upper r upper lobe pneumonia
Term
Ziehl Neelson and Kinyoum stains
Definition
stains used in past carbol fuschin mycolic acid uptake
Term
micro labs currentlu use
Definition
auramine rhodamine
Term
micro labs currentlu use
Definition
auramine rhodamine stain
Term
micro labs currentlu use
Definition
auramine rhodamine stain
Term
micro labs currentlu use
Definition
auramine rhodamine stain
Term
tb fast or slow grow
Definition
slow
Term
doubling time of tb
Definition
15-20 hours
Term
10000/ml
Definition
required for dagnosis of tb
Term
THey used to use lowenstein jensen agar and middlebrook agar, now they use
Definition
bactec mgit-13 week average culture time
Term
lowenstien jensen agar is
Definition
gren and slow
Term
people with active tb
Definition
give it to other people
Term
how is it transfered
Definition
droplet nuclei from one person to another through air
Term
once you inhale a droplet nuclei
Definition
enters the lung alveoli.
tubercle bacilli mutliply in the alveoli
small number of bacilli enter blood stream and establish infection in distant sites
Term
2-10 weeks after infection
Definition
we create the hard shell. if we control we are laten
otherwise active.
Term
most common immunouppressive disease int he US
Definition
diabetics
Term
outside exposure vs inside
Definition
outside much better less risky
Term
8-10 active hours needed to
Definition
ensure transmission
can happen with less
Term
most common location of tb
Definition
lung
Term
more bacterial load youhave
Definition
greater number of infectious droplets creted
Term
sputum positive
Definition
5-10 K bacilli/ml
sputum negative can still transfer
Term
in hospital, how do we decrease chance of transmission?
Definition
pump air outside wear mask
Term
if you have never had tb you are more/less likely to get tb from a particular person than someone who has had tb
Definition
more likely
Term
scc tb rate
Definition
14/10000
Term
world average tb incidence
Definition
136/100k
africa 1000/100k
Term
where can you find high rates of tb
Definition
immigrants, borders, natives
Term
bcg vaccine
Definition
bacillus calmette guerin
intradermal
used outside europe japan usa
less efficacy against adult than children
Term
who do you want to screen for tb
Definition
congregate living
health care workers
active
latent tb
Term
IGRA Test
Definition
based on the production of interferon gamma by lymphocytes in response to TB antigens

not produced by bcg vaccine strains
Term
varicella, hiv, tb, herpes
Definition
can all hide in places to evade immune system
Term
tb symptoms
Definition
fever, night chill, sweat, loss appetite, loss weight, easy tired, hemoptysis.
Term
ltbi drug regimen
Definition
9 months isoniazid
4 months ripamfin
inh and ripamfin 4 months
Term
dot improvement
Definition
61-91 percent effective increase
Term
drug regiment for tb
Definition
ripe for 2 months
ir for 4 months
Term
MOTT and NTM
Definition
nontuberculous mycobacetium
mycobacterium other than tuberculosis
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