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HHB Unit 1.4
Mutations
15
Biology
Not Applicable
05/26/2017

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Term
chromosomes
Definition
rod-like structure that contains the genetic material of an organism encoded into DNA
Term
gene mutations
Definition
mutations that occur within genes (S,I,D)
Term
deletion (of nucleotides)
Definition
single gene mutation involving removal of a nucleotide from a sequence
Term
insertion
Definition
single gene mutation in which an additional nucleotide is placed into a sequence
Term
substitution
Definition
single gene mutation in which one nucleotide is replaced by another
Term
missense
Definition
substitution mutation; a single nucleotide change results in a codon for a different amino acid
Term
nonsense
Definition
substitution mutation in which a codon is changed to a stop codon, shortening the resulting protein
Term
splice-site mutations
Definition
mutation at a point where coding (exons) and non-coding sections (introns) meet in a section of DNA
Term
frame shift mutations
Definition
type of gene mutations in which all the amino acids coded for after the mutation are changed
Term
chromosome mutations
Definition
mutations that affect the structure of chromosomes (D,D,I,T)
Term
duplication
Definition
chromosome mutation in which a sequence of genes is repeated on a chromosome
Term
deletion (of genes)
Definition
chromosome mutation in which a sequence of genes is lost from a chromosome
Term
translocation
Definition
chromosome mutation where part of a chromosome becomes attached to another chromosome (non-homologous partner)
Term
homologous chromosomes
Definition
Pairs of chromosomes that match each other, humans have 23 matching pairs
Term
inversion
Definition
chromosome mutation in which a section of the chromosome is removed, reversed and reinserted
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