Term
|
Definition
| RNA virus with 6 different genotypes. 1,3 an6 most prev in Asia |
|
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Term
|
Definition
| 2-3% of pop infected globally. Egypt has the highest prev with 22%. Become chronic in 75-85% of people infected and cirhosis or HCC in 0.1-5%. The leading risk factor is IDU. HCV only in 2-8% of children born to HCV postive mothers. 33% of PLWHA are infected with HCV. 170 million infevtions |
|
|
Term
| Interaction bw HCV and HIV |
|
Definition
| Coinfected have faster progression of liver fibrosis, reduces rate of spontaneous clearance of HCV, and perinatal HCV transmission is higher |
|
|
Term
|
Definition
| 2-6% in general population. 63% among IDU |
|
|
Term
| HCV Afghanistan among IDU |
|
Definition
| 36%. Risk factors indep associated: ever sharing needles, being an IDU >3yrs and receiving injecitons from non-medical practitioner |
|
|
Term
|
Definition
| Detection of Ab by EIA to recombinant HCV peptides. The sensitivity of the third generation EIA is approx 97% |
|
|
Term
| What factors are associated with a more rapid rate of disease progression in HCV? |
|
Definition
Male
Age >40 yrs
Alcohol consumption |
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|
