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Hemotology
exam 1
19
Biology
Undergraduate 4
08/13/2017

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Term
Adults have ......... of blood which contains ......... of formed elements and ......... of plasma.
Definition
6 liters, 45%, and 55%
Term
what are the most common WBC?
Definition
Neutrophils (segmented neutrophils are found more)
Term
what are platelets responsible for?
Definition
Blood clotting
Term
Samples for the Hematology lab are drawn in which type of a tube?
Definition
EDTA
Term
The plasma of the blood is composed of ......... water and ....... of solutes
Definition
92% of water and 8% of solutes
Term
what is the liquid portion of the blood called when the blood is allowed to clot?
Definition
It is called serum (once the fibrinogen is eliminated out the sample is called a serum sample)
Term
what is Hematopoiesis?
Definition
it is the production and the development of the cells characterized by a constant turnover of cells.
Term
The number of cells in the circulation is affected by:
Definition
1. Cell production
2. cell release
3. Cell destruction/survival
Term
Hemolytic anemia
Definition
The destruction of Red Blood Cells
Term
what is hemostasis?
Definition
It is the process by which the body spontaneously stops the bleeding and maintains the blood within the vascular system.
Term
What is Oxyhemoglobin?
Definition
It is a single oxygen molecule attached to the Fe+2 of an alpha chain heme. This causes the displacement of the molecule. The salt bridges between the hemoglobin of the tetrameter are broken.
Term
what are the normal hemoglobins present in the body?
Definition
Hemoglobin A (>95%) on the a2b2
Hemoglobin A2 (2-3%) on the a2g2
Hemoglobin F (<1%) on the a2y2
Term
What is Hemoglobin F?
Definition
It is also known as the fetal Hgb, it can be obtained in adulthood as well.
Term
What is Methemoglobin?
Definition
It is oxidized hemoglobin. (The iron Fe+2 is oxidized to ferric state Fe+3) Hgb is not functional and cannot combine with oxygen.
Term
what is Carboxyhemoglobin?
Definition
Formed when Hgb is exposed to carbon monoxide. Hg has greater affinity for CO than for O2. The bond is very hard to be broken.
Term
what is sulfhemoglobin?
Definition
a stable compound of hemoglobin and sulfur. This is irreversible process usually found in patients that have a sulfur containing medication in their body.
Term
Oxyhemoglobin Measurement
Definition
Measures only functional hemoglobin.
Term
The best method to measure hemoglobin
Definition
Spectrophotometer ( Drabkins reagents)
Term
Cyanmethemglobin
Definition
it is stable and can be standardized, this method of testing is recommended.
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