Term
Given the Etiology, Name the Coagulation Disorder associated with it:
Multiple mechanisms, but most decreased production of plasma coagulation factors |
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Definition
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Term
Given the Etiology, Name the Coagulation Disorder associated with it:
Related to diet or antibiotic use that destroys gut normal flora |
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Definition
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Term
Given the Etiology, Name the Coagulation Disorder associated with it:
Patient develops an autoantibody against phospholipids on platelet surfaces and in the PTT testing system |
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Definition
| Lupus Anticoagulants (also called anti-phospholipid antibodies, circulating anticoagulants, or nonspecific inhibitors) |
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Term
Given the Etiology, Name the Coagulation Disorder associated with it:
Something interferes with mechanisms that inhibit clotting |
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Definition
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Term
| Is Liver Disease Usually acquired or genetic? |
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Definition
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Term
| What is the cause of Vitamin K1 Disorder? |
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Definition
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Term
| What is the cause of Vitamin K2 Disorder? |
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Definition
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Term
True or False:
There are many genetic and acquired causes of excess blood clotting |
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Definition
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Term
| What will the PT & PTT be for Liver Disease? |
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Definition
INCREASED PT
INCREASED PTT |
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Term
| Which Coagulation Disorder will have slight to moderate thrombocytopenia with poor functioning INCREASED Liver Function Tests? |
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Definition
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Term
True or False:
PT will be elevated in Vitamin K Deficiency, but there may ALSO be a slight INCREASE in PTT |
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Definition
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Term
| Which factors are affected by Vitamin K Deficiency? |
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Definition
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Term
Given the Clinical description, list the coagulation disorder:
Moderate to Severe Bleeding |
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Definition
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Term
Given the Clinical description, list the coagulation disorder:
Mild - often only see if multiple factors are present |
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Definition
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Term
Given the Special Features, List the Coagulation Disorder associated with it:
Factor VIII NORMAL or INCREASED |
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Definition
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Term
| What is one of the most common hemostatic diseases? |
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Definition
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Term
| Why are premature infants given Vitamin K? |
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Definition
| Immature livers can't make factors and they have no gut bacteria, so vitamin K is given to premature infants to help them. |
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Term
True or False:
Many patients who develop LA (Lupus Anticoagulants) do NOT have an autoimmune disorder. |
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Definition
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Term
| How is Lupus Anticoagulants Disorder acquired? |
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Definition
| Acquired in patients with SLE and other auto immune disorders |
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Term
| What are the typical results associated with Acquired Thrombosis? |
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Definition
| INCREASED Lipids, Immobilization, & Inflammation |
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Term
| What are the typical results associated with Genetic Thrombosis? |
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Definition
| Activated Protein C resistance, & deficiencies in AT, Protein C, & Protein S |
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Term
Which Coagulation Disorder has the following diagnostic tests:
INCREASED PTT
50:50 Mix of patient plasma with Normal plasma does NOT CORRECT |
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Definition
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Term
| What tests would you perform to confirm Lupus Anticoagulant? |
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Definition
| Platelet Neutralization, DRVVT, or Anti-phospholipid assay |
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Term
| What test would you perform to diagnose Thrombosis? |
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Definition
| Factor V Leiden molecular test for activated protein C resistance |
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Term
True or False:
Other Thrombosis genetic conditions can be assayed by immunoassays in specialized labs |
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Definition
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Term
Given the Clinical Description, name the Coagulation Disorder associated with it:
Associated with thrombosis or miscarriages RATHER THAN Bleeding |
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Definition
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Term
| Thrombosis - Venous clots can break free & cause ____ ______ ______. |
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Definition
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Term
| Thrombosis - Arterial clots can cause ___ ____ & _____. |
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Definition
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Term
True or False:
LA affects coagulation testing but generally does NOT cause serious clinical problems |
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Definition
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Term
| What does Lupus Anticoagulant usually present with? |
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Definition
| Unexplained NORMAL PT & INCREASED PTT |
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Term
| How would/should you treat Thrombosis? |
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Definition
| Anticoagulant therapy or thrombolytic therapy (clot busters) |
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