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Hematology Internship Section 3
Coagulation/Hemostasis Coagulation Tests. Page 98
36
Biology
Undergraduate 4
10/14/2015

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Term
What is the reference range for the following Coagulation Test:

Factor Assay
Definition
50-150% of Normal
Term
Which Coagulation test is used to diagnose factor deficiencies and to determine how much of the factor is present?
Definition
Factor Assays
Term
Aged serum corrects the PTT in what factors?
Definition
Factors IX, XI, & XII
Term
Absorbed plasma corrects the PTT in what factors?
Definition
Factors VIII:C, XI, & XII
Term
Which coagulation test is used to confirm suspected LA with anti-phospholipid antibody?
Definition
Mixing Studies
Term
Given the principle, name the Coagulation test:

Patient plasma is mixed 1:1 with normal plasma.
Also, an older procedure when patient plasma is mixed with aged serum and absorbed plasma to determine which factor assay to run based on the correction or non-correction of the PTT.
Definition
Mixing Studies
Term
If the previously prolonged PTT does NOT correct (thus stays prolonged) with the mixing study, what is suspected but still needs to be confirmed?
Definition
Lupus anticoagulant
Term
If the prolonged PTT DOES Correct with the 1:1 mixture, what is suspected?
Definition
Factor Deficiency
Term
If the prolonged PTT DOES Correct with the 1:1 mixture, what test should be performed?
Definition
Factor Assays
Term
Given the following test result, name the Factor Deficiency that this older procedure indicates:

Aged Serum - Non-correction
Absorbed Plasma - Correction
Definition
Factor VIII:C Deficiency
Term
Given the following test result, name the Factor Deficiency that this older procedure indicates:

Aged Serum - Correction
Absorbed Plasma - Non-correction
Definition
Factor IX Deficiency
Term
Given the following test result, name the Factor Deficiencies that this older procedure indicates:

Aged Serum - Correction
Absorbed Plasma - Correction
Definition
Factors XI & XII Deficiency
Term
Given the principle, name the Coagulation test:

The clotting time of substrate plasma known to be deficient in the factor to be assayed is shortened or corrected by adding diluted factor-containing plasma. By using various dilutions of a standard, a standard curve is made. Unknown patient samples are derived by diluting the sample and converting the PTT in seconds to factor activity from the standard curve.
Definition
Factor Assays
Term
Given the principle, name the Coagulation test:

Aggregating agents (agonists) such as ADP, Collagen, Epinephrine, Arachidonic acid, and Ristocetin are added to (PRP) Platelet Rich Plasma. As platelets change shape and aggregate, the turbid PRP clears and transmits more light. O.D. is plotted against time. Curve created is compared to normal.
Definition
Platelet Aggregometry
Term
Given the Coagulation Cascade Diagram, Name letter "A"
[image]
Definition
XII
Term
Given the Coagulation Cascade Diagram, Name letter "B"
[image]
Definition
XII a
Term
Given the Coagulation Cascade Diagram, Name letter "C"
[image]
Definition
XI
Term
Given the Coagulation Cascade Diagram, Name letter "D"
[image]
Definition
XI a
Term
Given the Coagulation Cascade Diagram, Name letter "E"
[image]
Definition
IX
Term
Given the Coagulation Cascade Diagram, Name letter "F"
[image]
Definition
IX a
Term
Given the Coagulation Cascade Diagram, Name letter "G"
[image]
Definition
VII
Term
Given the Coagulation Cascade Diagram, Name letter "H"
[image]
Definition
VII a + Tissue Factor
Term
Given the Coagulation Cascade Diagram, Name letter "I"
[image]
Definition
VIII
Term
Given the Coagulation Cascade Diagram, Name letter "J"
[image]
Definition
VIII a
Term
Given the Coagulation Cascade Diagram, Name letter "K"
[image]
Definition
X
Term
Given the Coagulation Cascade Diagram, Name letter "L"
[image]
Definition
X a
Term
Given the Coagulation Cascade Diagram, Name letter "M"
[image]
Definition
V
Term
Given the Coagulation Cascade Diagram, Name letter "N"
[image]
Definition
V a
Term
Given the Coagulation Cascade Diagram, Name letter "O"
[image]
Definition
Prothrombin
Term
Given the Coagulation Cascade Diagram, Name letter "P"
[image]
Definition
Thrombin
Term
Given the Coagulation Cascade Diagram, Name letter "Q"
[image]
Definition
XIII
Term
Given the Coagulation Cascade Diagram, Name letter "R"
[image]
Definition
Fibrinogen
Term
Given the Coagulation Cascade Diagram, Name letter "S"
[image]
Definition
Fibrin Monomer
Term
Given the Coagulation Cascade Diagram, Name letter "T"
[image]
Definition
XIII a
Term
Given the Coagulation Cascade Diagram, Name letter "U"
[image]
Definition
Fibrin Polymer
Term
Given the Coagulation Cascade Diagram, Name letter "V"
[image]
Definition
Cross-Linked Fibrin Polymer (Clot)
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