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Definition
RBCs w/ high membrane:Hb ratio (due to RBC dehydration)
Associated w/ HbC, HbS/HbC, Asplenia, Thallasemia, Fe-def anemia |
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Term
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Definition
| small nuclear remnants seen w/ asplenia |
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Definition
| Seen in G6PD def from splenic macrophages phagocytosing Heinz bodies |
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Definition
| seen in G6PD def: oxidative damage causes sulfahydryl groups on Hb to polymerize --> Hb precipitation |
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Definition
| seen in spherocytosis: microcytic, hyperchromic cell from removal of RBC membrane |
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Definition
RBCs are unequal size
(remember anisocoria, uneven pupil size) |
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Term
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Definition
abnormal shaped RBCs
TYPES:
*MEMEBRANE ABNORMALITIES
- Acanthocytes or Spur/Spike cells
- Codocytes or Target cells
- Echinocytes and Burr cells
- Elliptocytes and Ovalocytes
- Spherocytes
- Stomatocytes or Mouth cells
- Drepanocytes or Sickle Cells
- Degmacytes or "bite cells"
*TRAUMA
- Dacrocytes or Teardrop Cells
- Keratocytes
- Microspherocytes and Pyropoikilocytes
- Schistocytes
- Semilunar bodies |
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Term
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Definition
| erythroid progenitor cells; Parvovirus B19 can infect them and cause an aplastic crisis in susceptible people (i.e. people w/ chronic hemolytic anemias that need high RBC turnover) |
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Definition
Associated w/ toxic injury to bone marrow:
- Sideroblastic anemia
- Lead poisoning
- Beta thalassemia |
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Term
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Definition
| immature nucleated RBCs & immature granulocytes in blood: sign of myelophthisic anemia (e.g. bone mets) |
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Definition
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