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Hematologic system intro
Linton
40
Nursing
Undergraduate 1
06/19/2023

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Term
structures and components of the hematologic system
Definition
Bone marrow
Liver
Spleen
Blood
Red blood cells (erythrocytes)
Platelets (thrombocytes)
Clotting factors
Plasma
Term
the primary functions of the hematologic system
Definition
oxygenation and hemostasis
Term
majority of rbcs and plts are produced in the
Definition
vertebrae, ribs, sternum, skull, pelvis and long bones of the legs
Term
the kidneys manufacture
Definition
hematopoietin
Term
stiumlates the prodcuaiton of RBCs in the bone marow
Definition
hematopoietin
Term
the liver manufactures
Definition
clotting factor and clears old/damaged RBCs form circulation
Term
removes old RBCs form circulation
Definition
spleen
Term
the clear straw colored lfuid that carries the RBCs, platelets and clotting factors thorugh the circulatory system
Definition
plasma
Term
control of bleeding process
Definition
Blood vessel constricts; reduces bleeding
Platelets adhere to the injured blood vessel, forming an unstable platelet plug
Coagulation initiated, forming a stable fibrin matrix (scab)
Term
pt with low rbc counts may experience
Definition
orthostatic changes
Term
petechiae signal
Definition
low plt count
Term
pt with low rbc counts often are
Definition
dyspneic or short of breath
Term
pt with low rbc counts can be tachycardic with a heart rate greater than
Definition
100 bpm
Term
indicats the 02 carrying capacity in the blood
Definition
hgb
Term
the percentage of rbcs in whole blood
Definition
hct
Term
the spleen removes _ from circulation
Definition
old RBCs
Term
increased WBCs are consistent with
Definition
infection, inflammation, tissue necrosis or leukemic neoplasia
Term
a low WBC count reflects reduced
Definition
bone marrow activity
Term
normal plately counts range from
Definition
140,00 to 440,000 platelts/mm3
Term
neutrophils increase in the presence of
Definition
acute bacterial infections or trauma
Term
Nursing actions for the patient at Risk for injury from low red blood cell counts
Definition
adminster 02 as prescribed
adminsiter blood products as prescribed
administer the hematopoietic growth factor erythropoietin as prescribed
monitor position changes from bed or chair to standing to ensure safety
allow for rest between periods of activity because the patient with anemia can tire easily
elevate the patient's head on pillows for shortness of breath
provide extra blankets if the patient feels too cool
theach the patient and family about the underlying pathophysiology and how to manage the symptoms of anemia
Term
: universal donors because their blood does not contain any of the A, B, or Rh antigens and can safely be given to anyone
Definition
O negative
Term
universal recipients because blood contains the A, B, and Rh antigens; they can safely receive any type of blood
Definition
AB positive:
Term
platelet transfusions are given when platelets fall below _ or if the pt is _
Definition
20,000, actively bleeding
Term
four main types of reactions to blood transfusions
Definition
hemolytic, anaphylactic, febrile, circulatory overload
Term
Naturally occurring hormones that stimulate the bone marrow to produce more blood cells
Definition
colony stimulating factors
Term
Stimulates bone marrow to produce more red blood cells
Definition
erythropoietin and darbepoetin
Term
colony stimulating factors
Definition
erythropietin, darbepoetin, oprelvekin
Term
stimulates the bone marrow to prduce more platelets
Definition
oprelvekin
Term
the liver also manufactures clotting factors such as
Definition
fibrinogen, prothrombin, thromboplastin
Term
control of bleeding when injury occurs
Definition
hemiostasis
Term
_ on the corner of mouth can indicate vitamin deficiencey
Definition
cracking
Term
changes in vital signs that indicate hemotological disorders
Definition
tachypnea, tachycardia, orthostatic hypotension
Term
differences in petechiae, purpura, ecchymosis
Definition
petechiae: 1-3 mm
purpura: 3mm or more
ecchymosis = bruising
Term
heart rate increases in pt with low RBC count because _ which increases o2 supply
Definition
cardiac output increases
Term
_ can become enlarged causing abdominal tenderness
Definition
liver and spleen
Term
ratio for hgb to hct is usually
Definition
1:3
Term
normal fibrinogen
Definition
200-400 in adults (<100 is critical)
Term
when giving blood the needle should be
Definition
18-20g
Term
for each unit of packed rbc transfused the hgb should increase _ and the hct _
Definition
1 g/dL, 3%
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